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Association of group B streptococcus colonization with early term births

  • Alexandria J. Hill EMAIL logo , Alicia Sanders , Gwen Baillargeon und Ramkumar Menon
Veröffentlicht/Copyright: 28. August 2014
Journal of Perinatal Medicine
Aus der Zeitschrift Journal of Perinatal Medicine Band 43 Heft 5

Abstract

Objective: The objective of this study was to reproduce and validate the association of group B streptococcus (GBS) colonization resulting in early-term birth (370/7–386/7 weeks’ gestation) and lower birth weight, reported in African-American and Caucasian populations, in a Hispanic cohort.

Methods: GBS status of women 18–40 years of age with uncomplicated pregnancies who experienced spontaneous labor and vaginal delivery between 370/7 and 420/7 weeks’ gestation over 5 years were identified. Bivariate analysis was conducted on stratified data (GBS+ vs. GBS–) to assess relationship to early versus late-term delivery. Chi-square, Fisher’s exact, and Student’s t-tests were used for analysis.

Results: Our cohort was 86% Hispanic, with a GBS+ rate of 10%. No difference for mean gestational age at delivery for GBS+ (275.9 days±6.8) vs. GBS– (275.6 days±6.9) was seen (P-value=0.61). Birth weight for GBS+ and GBS– groups were similar (3388.5 g±388.6 vs. 3395.1 g±401.7, P-value=0.86).

Conclusions: In specific evaluation of Hispanic women experiencing spontaneous, term, vaginal delivery, GBS colonization does not result in early-term delivery. This is not consistent with prior data in the African-American and Caucasian population suggesting racial disparity in outcomes related to GBS colonization.

Keywords: Early term; group B streptococcus; infection; term gestation; vaginal delivery
Corresponding author: Alexandria J. Hill, MD, 301 University Blvd, Galveston, TX, USA, Phone: 409-772-2999, Fax: 409-772-2261, E-mail:

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2014-4-16
Accepted: 2014-7-25
Published Online: 2014-8-28
Published in Print: 2015-9-1

©2015 by De Gruyter

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Risk factors for preterm birth and new approaches to its early diagnosis
  4. Review
  5. Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?
  6. Original articles – Obstetrics
  7. The association of first trimester bleeding with preterm delivery
  8. Cervical sonoelastography for improving prediction of preterm birth compared with cervical length measurement and fetal fibronectin test
  9. The neuroprotective effect of magnesium sulfate in preterm fetal mice
  10. Correlation of cervical length, fetal fibronectin, phIGFBP-1, and cytokines in spontaneous preterm birth up to 14 days from sampling
  11. The unborn smoker: association between smoking during pregnancy and adverse perinatal outcomes
  12. Association of group B streptococcus colonization with early term births
  13. Association of maternal whole blood fatty acid status during the prenatal period with term birth dimensions: a cross-sectional study
  14. Predicting onset of labor from echogenicity of the cervical gland area on vaginal ultrasonography at term
  15. Disparity in post-treatment maternal circulating magnesium sulfate levels between twin and singleton gestation: Is this the missing link between plurality and adverse outcome?
  16. Original articles – Fetus
  17. Cardiovascular profile score in 44 fetuses with cervicofacial tumors
  18. First trimester tricuspid regurgitation and fetal abnormalities
  19. Gastroschisis: incidence and prediction of growth restriction
  20. Original articles – Newborn
  21. Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis
  22. First- and fifth-minute Apgar scores of 0–3 and infant mortality: a population-based study in São Paulo State of Brazil
  23. Feeding the feeble: steps towards nourishing preterm infants
  24. Book review
  25. Hot topics in perinatal medicine
  26. Erratum
  27. Erratum to: Impact of the nitric oxide-donor pentaerythrityl-tetranitrate on perinatal outcome in risk pregnancies: a prospective, randomized, double-blinded trial
  28. Congress Calendar
  29. Congress Calendar
https://doi.org/10.1515/jpm-2014-0129
Schlagwörter für diesen Artikel
Early term; group B streptococcus; infection; term gestation; vaginal delivery

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Risk factors for preterm birth and new approaches to its early diagnosis
  4. Review
  5. Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?
  6. Original articles – Obstetrics
  7. The association of first trimester bleeding with preterm delivery
  8. Cervical sonoelastography for improving prediction of preterm birth compared with cervical length measurement and fetal fibronectin test
  9. The neuroprotective effect of magnesium sulfate in preterm fetal mice
  10. Correlation of cervical length, fetal fibronectin, phIGFBP-1, and cytokines in spontaneous preterm birth up to 14 days from sampling
  11. The unborn smoker: association between smoking during pregnancy and adverse perinatal outcomes
  12. Association of group B streptococcus colonization with early term births
  13. Association of maternal whole blood fatty acid status during the prenatal period with term birth dimensions: a cross-sectional study
  14. Predicting onset of labor from echogenicity of the cervical gland area on vaginal ultrasonography at term
  15. Disparity in post-treatment maternal circulating magnesium sulfate levels between twin and singleton gestation: Is this the missing link between plurality and adverse outcome?
  16. Original articles – Fetus
  17. Cardiovascular profile score in 44 fetuses with cervicofacial tumors
  18. First trimester tricuspid regurgitation and fetal abnormalities
  19. Gastroschisis: incidence and prediction of growth restriction
  20. Original articles – Newborn
  21. Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis
  22. First- and fifth-minute Apgar scores of 0–3 and infant mortality: a population-based study in São Paulo State of Brazil
  23. Feeding the feeble: steps towards nourishing preterm infants
  24. Book review
  25. Hot topics in perinatal medicine
  26. Erratum
  27. Erratum to: Impact of the nitric oxide-donor pentaerythrityl-tetranitrate on perinatal outcome in risk pregnancies: a prospective, randomized, double-blinded trial
  28. Congress Calendar
  29. Congress Calendar
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