The effect of the use of oxytocin on blood loss during different postpartum periods
-
Ulaş Fidan
,
Uğur Keskin
Abstract
Objective: Postpartum hemorrhage is the most important reason for maternal mortality. In developed countries, the reason of 13% of maternal deaths is postpartum hemorrhage while this percentage reaches more than 30% in other countries. In this study, the effect of oxytocin use in different times at the 3rd stage of delivery on changes in the postpartum hemoglobin levels was compared.
Design and setting: In the study, 89 pregnant women to whom oxytocin was administered after placenta separation were studied in Group 1, 89 pregnant women were included in Group 2, and oxytocin was administered after delivery of the shoulder. The levels of hemoglobin and hematocrit before and after delivery were quantified.
Results: The biochemical parameters were examined, there was no significant statistical differences in the levels of hemoglobin and hemotocrit before delivery between the two groups. When compared to Group 1, Δ-hemoglobin (P=>0.001), Δ-hematocrit (P=>0.001), the change between the prepartum and postpartum hemoglobin percentage (P<=0.001), and change between the prepartum and postpartum hemotocrit percentage (P<=0.001) were statistically lower in Group 2.
Conclusions: It was determined that the use of oxytocin after shoulder delivery has more effects on decreasing the amount of postpartum hemorrhage.
References
[1] Afshari P, Medforth J, Aarabi M, Abedi P, Soltani H. Management of third stage labour following vaginal birth in Iran: A survey of current policies. Midwifery. 2014;30:65–71.10.1016/j.midw.2013.02.002Suche in Google Scholar PubMed
[2] Cindy WS. Postpartum hemorrhage. Prim Care. 2012;39: 167–87.10.1016/j.pop.2011.11.009Suche in Google Scholar PubMed
[3] de Castro Parreira MV, Gomes NC. Preventing postpartum haemorrhage: active management of the third stage of labour. J Clin Nurs. 2013;22:3372–87.10.1111/jocn.12361Suche in Google Scholar PubMed
[4] Edhi MM, Aslam HM, Nagvi Z, Hashmi H. Postpartum hemorrhage: causes and management. BMC Res Notes. 2013;6:236.10.1186/1756-0500-6-236Suche in Google Scholar PubMed PubMed Central
[5] Elbourne DR, Prendiville WJ, Carroli G, Wood J, McDonald S. Prophylactic use of oxytocin in the third stage of labor. The Cochrane Database Syst Rev. 2013;10:CD001808.Suche in Google Scholar
[6] Haeri S, Dildy GA. 3rd. Maternal mortality from hemorrhage Semin Perinatol. 2012;36:48–55.10.1053/j.semperi.2011.09.010Suche in Google Scholar
[7] Huh WK, Chelmow D, Malone FD. A double-blinded, randomized, controlled trial of oxytocin at the beginning versus the end of the third stage of labour for prevention of postpartum hemorrhage. Gynecol Obstet Invest. 2004;58:72–6.10.1159/000078095Suche in Google Scholar PubMed
[8] Jackson K, Allbert J, Schemmer G, Elliot M, Humphrey A, Taylor J. A randomized controlled trial comparing oxytocin administration before and after placental delivery in the prevention of postpartum hemorrhage. Am J Obstet Gynecol 2001;185:873–7.10.1067/mob.2001.117363Suche in Google Scholar PubMed
[9] Lalonde A, Daviss BA, Acosta A, Herschderfer K. Postpartum hemorrhage today: ICM/FIGO initiative 2004–2006. Int J Gynaecol Obstet. 2006;94:243–53.10.1016/j.ijgo.2006.04.016Suche in Google Scholar PubMed
[10] Oladapo OT, Okusanya BO, Abalos E. Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour. Cochrane Database Syst Rev. 2012;2:CD009332.10.1002/14651858.CD009332.pub2Suche in Google Scholar PubMed
[11] Soltani H, Hutchon DR, Poulose TA. Timing of prophylactic uterotonics for the third stage of labour after vaginal birth. Cochrane Database Syst Rev. 2010;CD006173.10.1002/14651858.CD006173.pub2Suche in Google Scholar PubMed
[12] Zamora LA. A randomized controlled trial of oxytocin administered at the end of the second stage of labor versus oxytocin administered at the end of the third stage of labor in the prevention of postpartum hemorrhage. Philipp J Obstet Gynecol. 1999;23:125–33.Suche in Google Scholar
The authors stated that there are no conflicts of interest regarding the publication of this article.
©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Editorial
- Erich Saling – The Father of Prenatal and Perinatal Medicine—Dedication to his 90th birthday
- Original articles - Obstetrics
- A transcervical amniotic fluid collector: a new medical device for the assessment of amniotic fluid in patients with ruptured membranes
- Advanced cervical dilatation and spontaneous preterm labor: a comparison between twin and singleton gestations
- Comparison of a novel test for placental alpha microglobulin-1 with fetal fibronectin and cervical length measurement for the prediction of imminent spontaneous preterm delivery in patients with threatened preterm labor
- Does recent sexual intercourse during pregnancy affect the results of the fetal fibronectin rapid test? A comparative prospective study
- Usefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes
- Effect of blood on ROM diagnosis accuracy of PAMG-1 and IGFBP-1 detecting rapid tests
- Single versus combination tocolytic regimen in the prevention of preterm births in women: a prospective cohort study
- Recommendations of activity restriction in high-risk pregnancy scenarios: a Danish national survey
- Is pharmacologic research on pregnant women with psychoses ethically permissible?
- Women’s knowledge and attitude towards pregnancy in a high-income developing country
- Impact of maternal body mass index on the cesarean delivery rate in Germany from 1990 to 2012
- Justified skepticism about Apgar scoring in out-of-hospital birth settings
- The effect of the use of oxytocin on blood loss during different postpartum periods
- Original articles - Fetus
- The T/QRS ratio values in pregnancies complicated by threatened preterm labour treated with intravenous infusions of fenoterol
- Cardiotocography patterns and risk of intrapartum fetal acidemia
- Combined spinal epidural analgesia for labor using sufentanil epidurally versus intrathecally: a retrospective study on the influence on fetal heart trace
- Original articles - Newborn
- Predicting fetal growth deviation in parous women: combining the birth weight of the previous pregnancy and third trimester ultrasound scan
- Letter to the Editor
- A cerclage is not a modified total cervical occlusion!
- Letter Reply
- Reply to: a cerclage is not a modified Total Cervical Occlusion!
- Congress Calendar
- Congress Calendar
Artikel in diesem Heft
- Frontmatter
- Editorial
- Erich Saling – The Father of Prenatal and Perinatal Medicine—Dedication to his 90th birthday
- Original articles - Obstetrics
- A transcervical amniotic fluid collector: a new medical device for the assessment of amniotic fluid in patients with ruptured membranes
- Advanced cervical dilatation and spontaneous preterm labor: a comparison between twin and singleton gestations
- Comparison of a novel test for placental alpha microglobulin-1 with fetal fibronectin and cervical length measurement for the prediction of imminent spontaneous preterm delivery in patients with threatened preterm labor
- Does recent sexual intercourse during pregnancy affect the results of the fetal fibronectin rapid test? A comparative prospective study
- Usefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes
- Effect of blood on ROM diagnosis accuracy of PAMG-1 and IGFBP-1 detecting rapid tests
- Single versus combination tocolytic regimen in the prevention of preterm births in women: a prospective cohort study
- Recommendations of activity restriction in high-risk pregnancy scenarios: a Danish national survey
- Is pharmacologic research on pregnant women with psychoses ethically permissible?
- Women’s knowledge and attitude towards pregnancy in a high-income developing country
- Impact of maternal body mass index on the cesarean delivery rate in Germany from 1990 to 2012
- Justified skepticism about Apgar scoring in out-of-hospital birth settings
- The effect of the use of oxytocin on blood loss during different postpartum periods
- Original articles - Fetus
- The T/QRS ratio values in pregnancies complicated by threatened preterm labour treated with intravenous infusions of fenoterol
- Cardiotocography patterns and risk of intrapartum fetal acidemia
- Combined spinal epidural analgesia for labor using sufentanil epidurally versus intrathecally: a retrospective study on the influence on fetal heart trace
- Original articles - Newborn
- Predicting fetal growth deviation in parous women: combining the birth weight of the previous pregnancy and third trimester ultrasound scan
- Letter to the Editor
- A cerclage is not a modified total cervical occlusion!
- Letter Reply
- Reply to: a cerclage is not a modified Total Cervical Occlusion!
- Congress Calendar
- Congress Calendar
