Abstract
Background: Premature adrenarche (PA), the appearance of pubic hair before the age of 8 years in girls and before 9 years in boys, may predict future morbidity, such as metabolic syndrome (MS).
Objective: The purpose of this study is to assess carotid artery ultrasound changes in children with PA.
Design/methods: PA children were matched with a group of prepubertal controls without PA. Subjects and controls underwent clinical and biochemical evaluation and sonograms of the carotid arteries.
Results: Twelve children with PA and their matched controls were studied. Carotid artery ultrasonography showed elevation of the inner and outer diameter of the left carotid, and the cross-sectional area of the lumen and outer wall, and the outer diameter of the right carotid artery in PA. However, none of the above results maintained statistical significance when a Hochberg correction was applied.
Conclusions: Carotid artery diameter and cross-sectional area may be useful non-invasive markers of vascular pathology and MS in premature pubarche.
©2012 by Walter de Gruyter Berlin Boston
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- Meetings
- Meetings Calendar
- Prelims
- Prelims
Articles in the same Issue
- Editorial
- 10.1515/jpem-2012-0999
- Reviews
- Sertoli cell markers in the diagnosis of paediatric male hypogonadism
- Congenital hypothyroidism
- Images in Pediatric Endocrinology
- Autoimmune thyroid disease and allergic contact dermatitis: two immune-related pathologies in the same patient
- Metformin use in children with obesity and normal glucose tolerance – effects on cardiovascular markers and intrahepatic fat
- The effects of metformin on inflammatory mediators in obese adolescents with insulin resistance: controlled randomized clinical trial
- Prevalence of components of the metabolic syndrome according to birthweight among overweight and obese children and adolescents
- Association of early menarche age and overweight/obesity
- Serum chitotriosidase activity: is it a new inflammatory marker in obese children?
- Newer Doppler echocardiography techniques in assessment of heart function in obese patients
- Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents
- The relation of vitamin D deficiency with puberty and insulin resistance in obese children and adolescents
- Ultrasonographic description of brain cortex and cingulate sulcus development in Mexican neonates and infants with congenital hypothyroidism
- GH deficiency during the transition period: clinical characteristics before and after GH replacement therapy in two different subgroups of patients
- Therapy strategies in vitamin D deficiency with or without rickets: efficiency of low-dose stoss therapy
- Children with isolated hypospadias have different hormonal profile compared to those with associated anomalies
- Duplication of SOX9 is not a common cause of 46,XX testicular or 46,XX ovotesticular DSD
- Evaluation of self-assessment of pubertal maturation in boys and girls using drawings and orchidometer
- Lack of association between seroconversion and catch-up growth in children with celiac disease
- Changes in carotid artery sonogram in premature adrenarche
- Patient Reports
- Delayed diagnosis of adrenal hypoplasia congenita in a patient with a new mutation in the NR0B1 gene
- Encephalopathy and sinustachycardia in childhood a possible differential diagnosis
- Difficult treatment of consumptive hypothyroidism in a child with massive parotid hemangioma
- Androgen receptor CAG and GGN polymorphisms in boys with isolated hypospadias
- Bilateral bloody nipple discharge in a male infant: sonographic findings and proposed diagnostic approach
- 49, XXXXY syndrome: an Italian child
- Intraoperative sonographic localization of a fractured Supprelin implant in a pediatric patient: a case report
- A girl with Hajdu-Cheney syndrome and premature ovarian failure
- A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (POMC) gene in an Indian boy
- Hepatic dysfunction is associated with vitamin D deficiency and poor glycemic control in diabetes mellitus
- Severe hypercalcemia without hypercalciuria in a previously healthy infant
- Mucolipidosis type II (I-cell disease) masquerading as rickets: two case reports and review of literature
- A case of diabetes mellitus associated with Rett Syndrome
- Peripubertal hypoglycemia – an unusual cause
- A pediatric Conn syndrome case
- Clinical and genetic characteristics and effects of long-term growth hormone therapy in a girl with Floating-Harbor syndrome
- Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features
- Short Communication
- Known VDR polymorphisms are not associated with bone mineral density measures in pediatric Cushing disease
- Meetings
- Meetings Calendar
- Prelims
- Prelims