A 12-year-old girl presented signs and symptoms of hyperthyroidism. She had a firm goiter (II°) and she stated that she felt constant warmth, nervousness and experienced palpitations. Autoimmune hyperthyroidism was diagnosed (TSH 0.022 mIU/L↓; fT4 21.0 pmol/L; fT3 7.5 pmol/L↑; antithyroperoxidase antibodies 1148.0 U/mL↑; antithyroglobulin antibodies 41.4 U/mL; thyroid-stimulating hormone receptor antibodies 2.3 U/L↑). Thyroid ultrasound showed multiple hypoechogenic areas with increased vascular flow. During treatment with methimazole, a small hyperpigmented and moderately irritated region was found on the right side of the umbilicus. It was not an allergic skin reaction to methimazole but the classic contact allergic dermatitis, probably a result of nickel in her belt. Two years after stopping the treatment she returned to clinics. She was euthyroid but manifested a firm goiter and ultrasonographic features of autoimmune thyroid disease. The diagnostic work-up concerning antithyroid antibodies is mandatory to confirm the ongoing autoimmune process with a long-term significance.
©2012 by Walter de Gruyter Berlin Boston
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- Meetings
- Meetings Calendar
- Prelims
- Prelims
Artikel in diesem Heft
- Editorial
- 10.1515/jpem-2012-0999
- Reviews
- Sertoli cell markers in the diagnosis of paediatric male hypogonadism
- Congenital hypothyroidism
- Images in Pediatric Endocrinology
- Autoimmune thyroid disease and allergic contact dermatitis: two immune-related pathologies in the same patient
- Metformin use in children with obesity and normal glucose tolerance – effects on cardiovascular markers and intrahepatic fat
- The effects of metformin on inflammatory mediators in obese adolescents with insulin resistance: controlled randomized clinical trial
- Prevalence of components of the metabolic syndrome according to birthweight among overweight and obese children and adolescents
- Association of early menarche age and overweight/obesity
- Serum chitotriosidase activity: is it a new inflammatory marker in obese children?
- Newer Doppler echocardiography techniques in assessment of heart function in obese patients
- Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents
- The relation of vitamin D deficiency with puberty and insulin resistance in obese children and adolescents
- Ultrasonographic description of brain cortex and cingulate sulcus development in Mexican neonates and infants with congenital hypothyroidism
- GH deficiency during the transition period: clinical characteristics before and after GH replacement therapy in two different subgroups of patients
- Therapy strategies in vitamin D deficiency with or without rickets: efficiency of low-dose stoss therapy
- Children with isolated hypospadias have different hormonal profile compared to those with associated anomalies
- Duplication of SOX9 is not a common cause of 46,XX testicular or 46,XX ovotesticular DSD
- Evaluation of self-assessment of pubertal maturation in boys and girls using drawings and orchidometer
- Lack of association between seroconversion and catch-up growth in children with celiac disease
- Changes in carotid artery sonogram in premature adrenarche
- Patient Reports
- Delayed diagnosis of adrenal hypoplasia congenita in a patient with a new mutation in the NR0B1 gene
- Encephalopathy and sinustachycardia in childhood a possible differential diagnosis
- Difficult treatment of consumptive hypothyroidism in a child with massive parotid hemangioma
- Androgen receptor CAG and GGN polymorphisms in boys with isolated hypospadias
- Bilateral bloody nipple discharge in a male infant: sonographic findings and proposed diagnostic approach
- 49, XXXXY syndrome: an Italian child
- Intraoperative sonographic localization of a fractured Supprelin implant in a pediatric patient: a case report
- A girl with Hajdu-Cheney syndrome and premature ovarian failure
- A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (POMC) gene in an Indian boy
- Hepatic dysfunction is associated with vitamin D deficiency and poor glycemic control in diabetes mellitus
- Severe hypercalcemia without hypercalciuria in a previously healthy infant
- Mucolipidosis type II (I-cell disease) masquerading as rickets: two case reports and review of literature
- A case of diabetes mellitus associated with Rett Syndrome
- Peripubertal hypoglycemia – an unusual cause
- A pediatric Conn syndrome case
- Clinical and genetic characteristics and effects of long-term growth hormone therapy in a girl with Floating-Harbor syndrome
- Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features
- Short Communication
- Known VDR polymorphisms are not associated with bone mineral density measures in pediatric Cushing disease
- Meetings
- Meetings Calendar
- Prelims
- Prelims