Abstract
Background: Concurrent deficiencies of three hormones in patients with Turner’s syndrome (TS) have rarely been reported. Here, we describe a case of a young girl who had Turner’s syndrome with concomitant chronic lymphocytic thyroiditis, growth hormone deficiency, and hypothyroidism with cardiopericarditis.
Case: An 11-year-old girl was referred to the outpatient clinic because of short stature, ochriasis, and cardiopalmus. Her ultrasound revealed absence of ovarian tissue. Karyotype examination suggested Turner’s syndrome with sex hormone deficiency. She was found to have an abnormal thyroid gland and elevated thyroid stimulating hormone (TSH). A positive thyroid autoantibody titer confirmed the diagnosis of chronic lymphocytic thyroiditis with hypothyroidism. Furthermore, her growth hormone levels were well below normal.
Diagnosis: A multi-endocrine disorder, i.e., Turner’s syndrome with chronic lymphocytic thyroiditis, growth hormone deficiency, and hypothyroidism with cardiopericarditis was diagnosed. Growth hormone and thyroxin substitution therapy was suggested.
©2011 by Walter de Gruyter Berlin New York
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- Meetings
- Meetings Calendar
Articles in the same Issue
- Publisher’s Note
- Publisher’s Note
- Editorials
- What brings a child to the doctor? A lesson from hyperthyroidism
- Images in Pediatric Endocrinology
- Hypothalamic hamartoma causing precocious puberty in a female child
- Original Contributions
- Adiponectin moderates the relationship between adiposity and leptin in adolescents regardless of gender or race
- Obesity in children and adolescents: relationship to growth, pubarche, menarche, and voice break
- Studies of different female rat models of hypothalamic obesity
- Frequency of congenital hypothyroidism in neonatesin the Konya region, Turkey
- Thyroid dysfunctions in children detected in mass screening for congenital hypothyroidism
- A nutritional intervention study with hydrolyzed collagen in pre-pubertal Spanish children: influence on bone modeling biomarkers
- Neonatal screening for congenital adrenal hyperplasia: transitory elevation of 17-hydroxyprogesterone
- Evidence of insulin-like growth factor binding protein-3 proteolysis during growth hormone stimulation testing
- Pediatric 25-hydroxyvitamin D concentrationsin neurofibromatosis type 1
- Temperature-responsive and biodegradable PVA:PVP k30:poloxamer 407 hydrogel for controlled delivery of human growth hormone (hGH)
- Patient Report Letters
- A novel EIF2AK3 mutation leading to Wolcott-Rallison syndrome in a Chinese child
- Neurological Wilson’s disease with refractory rickets
- HNF1A mutation presenting with fetal macrosomia and hypoglycemia in childhood prior to onset of overt diabetes
- Pediatric Cushing’s disease due to pituitary hyperplasia
- A 12-year-old Chinese girl with Cushing syndrome and virilization due to adrenocortical carcinoma
- Primary pigmented nodular adrenocortical disease: a case report in a 7-year-old girl
- Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure
- Transient hyperthyroidism due to acute suppurative thyroiditis in an adolescent female
- High frequency of cardiac and behavioral complaints as presenting symptoms of hyperthyroidism in children
- Aplasia cutis congenita in surviving co-twin after propylthiouracil exposure in utero
- Cushing syndrome due to ectopic adrenocorticotropic hormone secretion in a 3-year-old child
- Familial occurrence of Turner syndrome: casual event or increased risk?
- Mature teratoma, a rare cause of virilization in adolescence
- Co-existence of ADHD, autoimmune hypothyroidism and pituitary macroadenoma presenting in a behaviour clinic: a case report and brief review of the literature
- Virilizing para-adrenocortical adenoma associated with idiopathic-acquired generalized anhidrosis in an adolescent girl
- Concurrent occurrence of chronic lymphocytic thyroiditis with hypothyroidism and growth hormone deficiency in a Turner’s syndrome patient
- Patient report: sacral agenesis with hypopituitarism
- Meetings
- Meetings Calendar