Abstract
Objective: The relationships between obesity, pubertal development, and height are controversial. Therefore, we compared the prevalence of pubarche, menarche, and voice break between a large collective of obese and normal-weight children and adolescents aged 10–16 years.
Methods: We assessed weight, height, pubarche, menarche, and voice break in 1383 obese German children and in 6615 children of a representative national German cohort aged 10–16 years. In all obese children, gonadotropins were determined and birth weight data were collected.
Results: Independently of gender, the height standard deviation score (SDS) was significantly greater (0.3–1.0) in obese children <14 years compared to the reference cohort. Independently of age, the percentage of obese boys with pubarche was significantly lower compared to age-matched normal-weight boys. In girls <13 years, the prevalence of obese girls with pubarche was significantly lower compared to age-matched normal-weight girls. In boys ≥11 years, the percentage of obese boys with change of voice was significantly lower compared to age-matched normal-weight boys. In girls ≥11 years, the prevalence of obese girls with menarche was significantly lower compared to age-matched normal-weight girls. Birth weight had no impact on pubarche in the obese children. Luteinizing hormone was >0.3 IU/L in 86% of the children ≥10 years with pubarche.
Conclusions: Obese children are taller than normal-weight children up to the age of 14 years. Since obese children demonstrated pubarche, menarche, and voice break later than their normal-weight peers, the increase in height in obese children does not seem to be attributable to earlier onset of puberty.
©2011 by Walter de Gruyter Berlin New York
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- Meetings
- Meetings Calendar
Articles in the same Issue
- Publisher’s Note
- Publisher’s Note
- Editorials
- What brings a child to the doctor? A lesson from hyperthyroidism
- Images in Pediatric Endocrinology
- Hypothalamic hamartoma causing precocious puberty in a female child
- Original Contributions
- Adiponectin moderates the relationship between adiposity and leptin in adolescents regardless of gender or race
- Obesity in children and adolescents: relationship to growth, pubarche, menarche, and voice break
- Studies of different female rat models of hypothalamic obesity
- Frequency of congenital hypothyroidism in neonatesin the Konya region, Turkey
- Thyroid dysfunctions in children detected in mass screening for congenital hypothyroidism
- A nutritional intervention study with hydrolyzed collagen in pre-pubertal Spanish children: influence on bone modeling biomarkers
- Neonatal screening for congenital adrenal hyperplasia: transitory elevation of 17-hydroxyprogesterone
- Evidence of insulin-like growth factor binding protein-3 proteolysis during growth hormone stimulation testing
- Pediatric 25-hydroxyvitamin D concentrationsin neurofibromatosis type 1
- Temperature-responsive and biodegradable PVA:PVP k30:poloxamer 407 hydrogel for controlled delivery of human growth hormone (hGH)
- Patient Report Letters
- A novel EIF2AK3 mutation leading to Wolcott-Rallison syndrome in a Chinese child
- Neurological Wilson’s disease with refractory rickets
- HNF1A mutation presenting with fetal macrosomia and hypoglycemia in childhood prior to onset of overt diabetes
- Pediatric Cushing’s disease due to pituitary hyperplasia
- A 12-year-old Chinese girl with Cushing syndrome and virilization due to adrenocortical carcinoma
- Primary pigmented nodular adrenocortical disease: a case report in a 7-year-old girl
- Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure
- Transient hyperthyroidism due to acute suppurative thyroiditis in an adolescent female
- High frequency of cardiac and behavioral complaints as presenting symptoms of hyperthyroidism in children
- Aplasia cutis congenita in surviving co-twin after propylthiouracil exposure in utero
- Cushing syndrome due to ectopic adrenocorticotropic hormone secretion in a 3-year-old child
- Familial occurrence of Turner syndrome: casual event or increased risk?
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- Co-existence of ADHD, autoimmune hypothyroidism and pituitary macroadenoma presenting in a behaviour clinic: a case report and brief review of the literature
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- Concurrent occurrence of chronic lymphocytic thyroiditis with hypothyroidism and growth hormone deficiency in a Turner’s syndrome patient
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- Meetings
- Meetings Calendar