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A mixed-method randomized feasibility trial evaluating progressive muscle relaxation or autogenic training on depressive symptoms and quality of life in people living with human immunodeficiency virus (HIV) who have depressive symptoms

  • Maria Pilar Ramirez-Garcia ORCID logo EMAIL logo , Jérôme Leclerc-Loiselle ORCID logo , Marie-Pierre Gagnon , José Côté , Marie-Josée Brouillette and Réjean Thomas
Published/Copyright: July 3, 2020
Journal of Complementary and Integrative Medicine
From the journal Journal of Complementary and Integrative Medicine Volume 18 Issue 1

Abstract

Background

Progressive muscle relaxation (PMR) and autogenic training (AT) are effective relaxation techniques to reduce depressive symptoms. However, no studies on their effectiveness have been conducted among people living with HIV and depressive symptoms. The primary aim of this pilot study was to assess the feasibility and acceptability of PMR and AT interventions among people living with HIV who have depressive symptoms. A secondary aim was to assess the potential effectiveness of these interventions on depressive symptoms and quality of life.

Methods

This study was a three-arm pilot randomized control trial with mixed methods. Participants were randomized to PMR, AT, or a control group (CG), with four assessments (baseline, and at one, three, and six months). The PMR and AT interventions consisted of six 1 h sessions of individual training over 12 weeks, plus home practice. Recruitment, attrition, and completion rates were calculated. Depressive symptoms and quality of life were assessed at all times. Participants' perceptions of the interventions were collected in semi-structured interviews.

Results

Following the screening, 54/63 people met the inclusion criteria, and 42/54 were randomly allocated to the PMR group (n=14), AT group (n=14), and CG (n=14). Six participants (43%; 95% CI 18–71%) in the PMR group and 10 (71%; 95% CI 42–92%) in the AT group completed the intervention. Participants reported better emotion management and improvements in depressive symptoms and quality of life.

Conclusions

The pilot study suggests that a randomized trial to test the effectiveness of these interventions is feasible.

Trial registration

ClinicalTrials.gov NCT01901016

Keywords: autogenic training; depression; HIV; progressive muscle relaxation; quality of life
Corresponding author: Maria Pilar Ramirez-Garcia, RN Ph.D., Associate professor, Faculty of Nursing, Université de Montréal, Montréal, Quebec, Canada; and Research Center of the Centre Hospitalier de l', Université de Montréal, Montréal, Quebec, Canada; and Quebec Nursing Intervention Research Network (RRISIQ), Quebec, Canada; and C.P. 6128, succ. Centre-ville, Montréal, H3C 3J7, Quebec, Canada, E-mail: .

Funding source: Université Laval – Faculty of Nursing

Funding source: Quebec Nursing Intervention Research Network, Université Laval

Funding source: Canadian Institutes of Health Research

  1. Research funding: This research was funded by the Quebec Network on Nursing Intervention Research and Faculty of Nursing, Université Laval. The publication charges for this article were funded by a Planning and Dissemination Grant from the Canadian Institutes of Health Research, with the grant number PCS155284.

  2. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  3. Competing interests: The funding organization played no role in the study design; in the collection, analysis, and interpretation of the data; in the writing of the report; or in the decision to submit the report for publication.

  4. Informed consent: Informed consent was obtained from all individuals included in this study.

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Received: 2019-06-26
Accepted: 2020-01-06
Published Online: 2020-07-03

© 2020 Walter de Gruyter GmbH, Berlin/Boston

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https://doi.org/10.1515/jcim-2019-0167
Keywords for this article
autogenic training; depression; HIV; progressive muscle relaxation; quality of life

Articles in the same Issue

  1. Frontmatter
  2. Reviews
  3. Endocannabinoids release after Osteopathic Manipulative Treatment. A brief review
  4. A pervasive scientific overview on mangiferin in the prevention and treatment of various diseases with preclinical and clinical updates
  5. Clinical trials of homeopathy in urological disorders: a systematic review
  6. Strategies in traditional Persian medicine to maintain a healthy life in the elderly
  7. Research articles Basic
  8. Cytoprotective and antisecretory properties of methanolic extract of Distemonanthus benthamianus (Caesalpiniaceae) stem bark on acute gastric ulcer in rats
  9. Screening chemical inhibitors for alpha-amylase from leaves extracts of Murraya koenigii (Linn.) and Aegle marmelos L.
  10. Ayurvedic formulations containing benzoic and ascorbic acids as additives: benzene formation during storage and impact of additives on quality parameters
  11. High cholesterol diet promotes dysfunction of arginase and cholinergic enzymatic system in rats: ameliorative role of caffeic and chlorogenic acids
  12. Cytokine and inflammatory mediators are associated with cytotoxic, anti-inflammatory and apoptotic activity of honeybee venom
  13. Anti-anaemic effect of ethanol leaf extract of Cnidosculus aconitifolius on cyclophosphomide-induced anaemia in rats
  14. Alterations in histological, biochemical and hematological parameters in Plasmodium berghei NK-65 infected balb/c mice treated with Bridelia ferruginea stem bark extract
  15. Structural characterization, antioxidant, and antibiofilm activities of Coffea canephora green seeds
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  18. Efficacy of Habbul aas (fruits of Myrtus communis) in menorrhagia: a single blinded randomized standard control study
  19. Ginger (Zingiber officinale) and turmeric (Curcuma longa L.) supplementation effects on quality of life, body composition, bone mineral density and osteoporosis related biomarkers and micro-RNAs in women with postmenopausal osteoporosis: a study protocol for a randomized controlled clinical trial
  20. Lithotriptic effect of Safūf Hajar-al Yahūd in patients of Hasat-ul Kilya (Nephrolithiasis) – an open prospective clinical validation trial
  21. Efficacy of Qurs-e-Gulnar in Ziabetus (type 2 Diabetes Mellitus): a single blind randomized controlled trial
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