Startseite Phytochemistry, bioactivity: suggestion of Ceratonia siliqua L. as neurodegenerative disease therapy
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Phytochemistry, bioactivity: suggestion of Ceratonia siliqua L. as neurodegenerative disease therapy

  • Imane Lakkab EMAIL logo , Hanane El Hajaji , Nadya Lachkar , Brahim El Bali , Mohammed Lachkar und Alin Ciobica
Veröffentlicht/Copyright: 29. Mai 2018
Journal of Complementary and Integrative Medicine
Aus der Zeitschrift Journal of Complementary and Integrative Medicine Band 15 Heft 4

Abstract

Carob tree (Ceratonia siliqua L.) is one of the most widespread medicinal plants in the Mediterranean area. Traditionally, it was cultivated for its ethnopharmacological benefits and, more especially, for the seeds, which served as unit of measurement of jewelers “carat.” Hence, in the last half-century, numerous studies reported a wide range of phytoconstituents contained in all parts of Ceratonia siliqua such as phenolic compounds, flavonoids, tannins, anthocyanins, alkaloids, glycosides, proteins and minerals. This review article unveils the phytochemical constituents, bioactivity and pharmacological studies of Ceratonia siliqua. Recent studies have shown that the extracts of this plant exhibit an antioxidant, antidiarrheal, antibacterial, antifungal, anti-inflammatory, antidiabetic activities and also hepatoprotective and antiproliferative effects. In this review, we provide a summary of the most interesting data related to bioactivity and therapeutic potential of Ceratonia siliqua in a way to suggest possible future studies that may use Ceratonia siliqua as an undeniable natural alternative for neurodegenerative diseases treatment.

Keywords: Ceratonia siliqua L.; neurodegenerative diseases; oxidative stress; phytochemistry

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

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Received: 2018-01-29
Accepted: 2018-04-14
Published Online: 2018-05-29

© 2018 Walter de Gruyter GmbH, Berlin/Boston

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https://doi.org/10.1515/jcim-2018-0013
Schlagwörter für diesen Artikel
Ceratonia siliqua L.; neurodegenerative diseases; oxidative stress; phytochemistry

Artikel in diesem Heft

  1. Pre-clinical Studies
  2. Acute and subacute toxicity of aqueous extract of the tuber of Kedrostis africana (L.) Cogn in Wistar rats
  3. Protective effects of persian honey, Apis Mellifera Meda Skorikov on side effects of chemotherapy and ischemia/reperfusion induced testicular injury
  4. Chemical composition and antioxidant activity of phenolic compounds and essential oils from Calamintha nepeta L.
  5. Analgesic, anti-inflammatory and anti-arthritic properties of aqueous and methanolic stem bark extracts from Nauclea pobeguinii (Rubiacee) in rats
  6. Testicular and spermatotoxic potential of methanol extract of red cultivar Allium cepa in rats
  7. Clinical Studies
  8. Premature ovarian failure of autoimmune etiology in 46XX patients: is there a hope?
  9. African crocus (Curculigo pilosa) and wonderful kola (Buchholzia coriacea) seeds modulate critical enzymes relevant to erectile dysfunction and oxidative stress
  10. Effect of foot reflexology and slow stroke back massage on the severity of fatigue in patients undergoing hemodialysis: A semi-experimental study
  11. Effects of Spiritist “passe” (Spiritual healing) on stress hormone, pain, physiological parameters and length of stay in preterm newborns: a randomized, double-blind controlled trial
  12. Short Communication
  13. A pilot-study of hypnotherapy as complementary treatment for pain in chronic pancreatitis
  14. Neuroprotective effect of curcumin nanoparticles against rat model of status epilepticus induced by pilocarpine
  15. Yoga practice to improve sleep quality and body composition parameters of obese male - a randomized controlled trial
  16. Association between a guided meditation practice, sleep and psychological well-being in type 2 diabetes mellitus patients
  17. Case study
  18. Effect of yoga and naturopathy on liver, renal and cardiorespiratory functions of a patient with hepatic cirrhosis with portal hypertension and ascites: a case report
  19. Review
  20. Phytochemistry, bioactivity: suggestion of Ceratonia siliqua L. as neurodegenerative disease therapy
  21. Abstracts
  22. 2018 INCAM Research Symposium: Complementary and Integrative Medicine Research in an Era of Skepticism
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