Effect of integrated yoga on anti-psychotic induced side effects and cognitive functions in patients suffering from schizophrenia
-
Meghnath Verma
,
Shivarama Varambally
Abstract
Background
Twenty one (12 females) subjects, diagnosed with schizophrenia by a psychiatrist using ICD-10, in the ages 52.87 + 9.5 years and suffering since 24.0 ± 3.05 years were recruited into the study from a schizophrenia rehabilitation center in Bengaluru.
Methods
All subjects were taking anti-psychotic medications and were in stable state for more than a month. Psychiatric medications were kept constant during the study period. Assessments were done at three points of time: (1) baseline, (2) after one month of usual routine (pre) and (3) after five months of validated Integrated Yoga (IY) intervention (post). Validated 1 h Yoga module (consisting of asanas, pranayama, relaxation techniques and chantings) was practiced for 5 months, five sessions per week. Antipsychotic-induced side effects were assessed using Simpson Angus Scale (SAS) and Udvalg for Kliniske Undersogelser (UKU) side effect rating scale. Cognitive functions (using Trail making Test A and B), clinical symptoms and anthropometry were assessed as secondary variables. Comparisons between “pre” and “post” data was done using paired samples t-tests after subtracting baseline scores from them respectively.
Results
At the end of five months, significant reduction in drug-induced Parkinsonian symptoms (SAS score; p=0.001) and 38 items of UKU scale was observed along with significant improvement in processing speed, executive functions and negative symptoms of schizophrenia patients. No side effects of Yoga were reported.
Conclusions
The present study provides preliminary evidence for usefulness of Integrated Yoga intervention in managing anti-psychotic-induced side effects.
Acknowledgments:
We are thankful to Dr Ranganathan for his support and to all the patients who cooperated during this research.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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Artikel in diesem Heft
- Pre-clinical Studies
- Terminalia Sericea aqueous leaf extract protects growing wistar rats against fructose-induced fatty liver disease
- Bioactive potential of Indian stinging plants leaf extract against pathogenic fungi
- In vitro anticholinesterase, antimonoamine oxidase and antioxidant properties of alkaloid extracts from kola nuts (Cola acuminata and Cola nitida)
- Neuroprotective Effects of the Anthocleista Schweinfurthii Gilg. (Loganiaceae) Stem Bark Extract in Postmenopause-Like Model of Ovariectomized Wistar Rats
- Antioxidant activity of carob seeds and chemical composition of their bean gum by– products
- Modulatory effect of some citrus (Citrus limon, Citrus reticulata, Citrus maxima) peels on monoamine oxidase, phosphodiesterase-5 and angiotensin-1 converting enzyme activities in rat heart homogenate
- Clinical Studies
- Ameliorative potential of acupressure on gestational diabetes mellitus: A randomized controlled trial
- Complementary medicine for laboring women: a qualitative study of the effects of reflexology
- Decreased anxiety after Dawood fasting in the pre-elderly and elderly
- Inhibitory effects of Tiliacora triandra (Colebr.) Diels on cholesterol absorption
- Evaluation of antipyretic activity of Belladonna and Pyrogenium ultrahigh dilutions in induced fever model
- Short Communication
- Effect of integrated yoga on anti-psychotic induced side effects and cognitive functions in patients suffering from schizophrenia
- Effect of mud pack to eyes on psychological variables in healthy volunteers: a pilot randomized controlled trial
- Review
- Ethnomedicinal, phytochemical and pharmacological profile of a mangrove plant Ceriops Decandra GriffDin Hou.
- Biological markers for the effects of yoga as a complementary and alternative medicine
