A review on pulmonary and mediastinal synovial sarcoma
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Kristin Purnama Dewi
,
Ivana Purnama Dewi
,
Iswanto Iswanto
and
Laksmi Wulandari
Abstract
Sarcoma is defined as a tumor located in the thoracic cavity. However, sarcoma can occur on every side of the body. Synovial sarcoma is a rare soft tissue tumor originating from pluripotent with a high malignancy rate. The most common predilection of synovial sarcoma is in the joints. Primary synovial sarcoma of the lung and mediastinum are rare tumors and generally malignant. There are only a few cases have been reported. Definite diagnosis is made by histopathological, immunohistochemistry, and cytogenetic examination. The management strategy for synovial sarcoma requires multimodality treatment with surgery, chemotherapy, and radiotherapy. However, effective and relatively non-toxic therapy for primary synovial sarcoma is still developed. The five years life expectancy is higher if the patient received adjuvant radiotherapy and/or chemotherapy after surgery.
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Research funding: The authors received no financial support for this article’s research, authorship, and/or publication.
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Author contributions: KPD and I conceived the idea, performed the literature search, and mainly designed the report. KPD were the major contributor to writing the manuscript. IPD has edited the manuscript for publication. I and LW reviewed the article before submission. All authors read and approved the final manuscript.
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Conflict of interest: The authors declare that there is no conflict of interest.
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Ethical approval: Not applicable.
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Informed consent: Not applicable.
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Articles in the same Issue
- Frontmatter
- Editorial
- The clinical potential of flavonoids in Peyronie’s disease
- Reviews
- Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory
- Diabetic wound healing approaches: an update
- Metformin: new applications for an old drug
- Bispecific antibodies and its applications: a novel approach for targeting SARS-Cov-2
- A review on pulmonary and mediastinal synovial sarcoma
- Original Articles
- Cytokine release by human bone marrow stromal cells isolated from osteoarthritic and diabetic osteoarthritic patients in vitro
- Antioxidant and anti-inflammatory effect of olive leaf extract treatment in diabetic rat brain
- Implication of nitrergic system in the anticonvulsant effects of ferulic acid in pentylenetetrazole-induced seizures in male mice
- The effects of G protein-coupled receptor 30 (GPR30) on cardiac glucose metabolism in diabetic ovariectomized female rats
- Effects of weight-bearing vs. non-weight-bearing endurance exercise on reducing body fat and inflammatory markers in obese females
- [Lys5,MeLeu9,Nle10]-NKA(4–10) induces neurokinin 2 receptor mediated urination and defecation and neurokinin 1 receptor mediated flushing in rats: measured using the rapid detection voiding assay
- Single 30 min treadmill exercise session suppresses the production of pro-inflammatory cytokines and oxidative stress in obese female adolescents
- Letter to the Editor
- Effect of tirzepatide on prediabetics and blood pressure with implications for future research
