Association of glycaemic status and outcomes in diabetic foot problems: a retrospective evidence from South India

Balamurugan Ramanathan; Ramesh Duraisamy; Balaji Tulse Dass Venkatramanasami; Manoj Kumar Abbas; Aswinram Balamurugan

doi:10.1515/jbcpp-2020-0198

Article

Association of glycaemic status and outcomes in diabetic foot problems: a retrospective evidence from South India

Balamurugan Ramanathan , Ramesh Duraisamy , Balaji Tulse Dass Venkatramanasami , Manoj Kumar Abbas and Aswinram Balamurugan

Published/Copyright: February 22, 2021

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From the journal Journal of Basic and Clinical Physiology and Pharmacology Volume 33 Issue 2

Abstract

Objectives

Emerging shreds of evidence indicates that the risk of diabetic foot ulcer and associated morbidity can be reduced through the intensive glycemic control. There are very few studies which assessed the effects of glycemic control on diabetic foot problems among Indian patients. We aimed to assess the effect of glycemic control on the outcomes of diabetic foot problems among adult type 2 diabetes (T2DM) patients with foot ulcers.

Methods

A cross sectional study was conducted among the T2DM patients from a tertiary care teaching hospital in South India. The demographic characters, risk factors, treatment characters, glycemic status were collected among the patients and analyzed against the outcomes of diabetic foot ulcers by reviewing their medical records. Descriptive statistics were used to present the data. The Chi-square test and ANOVA were used for was used for the categorical variables and continuous parameters to identify the factors affecting the outcomes, respectively. All analysis was performed in SPSS v21.

Results

Out of the 100 participants included in the study, 70% were male. The majority (78%) were from an age group of 40 to 70 years, and the mean age was found to be 59.91 ± 10.6 years. The mean duration of diabetes was 9.66 years. Only ankle-brachial Index score (p=0.001) was significantly associated with the type of ulcers, whereas other factors not (p>0.05). A high level of average HbA_1c, BMI, ABI index and poor glycemic status was associated with a significant debridement strategy and longer duration of hospitalization; however, it was not substantial.

Conclusion

Our study inferred that poor glycemic status is associated with a significant debridement strategy and longer duration of hospitalization. However, these findings need to be strengthened with adequately powered prospective studies.

Keywords: clinical outcome; diabetes; diabetic foot; glycemic control; treatment

Corresponding author: Dr. Balaji Tulse Dass Venkatramanasami, Assistant professor, Department of General Medicine, Karuna Medical College, Vilayodi, Chittur, Palakkad, Kerala, 678103, India, Phone: +91 8086908268, Fax: +91 8202571998, E-mail: publicationkdsc@gmail.com

Acknowledgments

Authors also would like to acknowledge Department of General Medicine, Karuna Medical College, for an enormous support and facilities for the best possible completion of this study

Research funding: None
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: Authors state no conflict of interest.
Informed consent: Informed consent was obtained from all individuals included in this study.
Ethical approval: An ethical approval was obtained from Institutional Ethics Committee (No. KMC/IHEC/10/2019).
Data availability statement: The data related to this article is not deposited in any repository. However, it can be made available upon request.

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Received: 2020-07-06

Accepted: 2020-10-30

Published Online: 2021-02-22

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Articles in the same Issue

https://doi.org/10.1515/jbcpp-2020-0198

Keywords for this article

clinical outcome; diabetes; diabetic foot; glycemic control; treatment