Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis
-
Proteesh Rana
,
Vandana Roy
Abstract
We report a 26-year-old male patient diagnosed with extensively drug-resistant pulmonary tuberculosis presenting with reversible bilateral toxic optic neuropathy induced by the use of linezolid along with high-dose isoniazid. The case emphasizes the importance of recognizing toxic optic neuritis in patients on antitubercular therapy. Prompt recognition and treatment of such adverse drug reactions will reduce the associated morbidity.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Sharma P, Sharma R. Toxic optic neuropathy. Indian J Ophthalmol 2011;59:137–41.10.4103/0301-4738.77035Suche in Google Scholar PubMed PubMed Central
2. The use of the WHO-UMC system for standardised case causality assessment. Available at: http//www.who-umc.org/Graphics/24734.pdf. Accessed: 4 Aug 2016.Suche in Google Scholar
3. Naranjo C, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239–45.10.1038/clpt.1981.154Suche in Google Scholar PubMed
4. Tripathi KD. Essentials of medical pharmacology. In: Macrolide, lincosamide, glycopeptide and other antibacterial antibiotics, 7th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd, 2013:758.10.5005/jp/books/12256_58Suche in Google Scholar
5. World Health Organization. Guidelines for the programmatic management of drug-resistant tuberculosis: emergency update 2008. Available at: http://apps.who.int/iris/bitstream/ 10665/43965/1/9789241547581_eng.pdf. Accessed: 30 Jul 2016.Suche in Google Scholar
6. Javaheri M, Khurana RN, O’Hearn TM, Lai MM, Sadun AA. Linezolid-induced optic neuropathy: a mitochondrial disorder? Br J Ophthalmol 2007;91:111–5.10.1136/bjo.2006.102541Suche in Google Scholar PubMed PubMed Central
7. Tripathi KD. Essentials of medical pharmacology. In: Antitubercular drugs, 7th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd, 2013:766–7.Suche in Google Scholar
8. Kulkarni HS, Keskar VS, Bavdekar SB, Gabhale Y. Bilateral optic neuritis due to Isoniazid (INH). Indian Paediatr 2010;47:533–5.10.1007/s13312-010-0083-5Suche in Google Scholar PubMed
9. Lim SA. Ethambutol-associated optic neuropathy. Ann Acad Med Singapore 2006;35:274–8.10.47102/annals-acadmedsg.V35N4p274Suche in Google Scholar PubMed
10. Sweetman SC, editor. Martindale. The complete drug reference, 35th ed. London: Pharmaceutical Press, 2007.Suche in Google Scholar
11. Magazine R, Pal M, Chogtu B, Nayak V. Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis. Indian J Pharmacol 2010;42:247–8.10.4103/0253-7613.68436Suche in Google Scholar PubMed PubMed Central
12. Kulkarni K, Del Priore LV. Linezolid induced toxic optic neuropathy. Br J Ophthalmol 2005;89:1664–5.10.1136/bjo.2005.074237Suche in Google Scholar PubMed PubMed Central
Supplementary Material
The online version of this article offers supplementary material (https://doi.org/10.1515/jbcpp-2018-0007).
©2019 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Reviews
- Immune response and inflammatory pathway of ulcerative colitis
- Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer
- Behavior and Neuroprotection
- Effect of caffeine on alcohol consumption and alcohol-induced conditioned place preference in rodents
- Reproduction
- Pubertal anabolic androgenic steroid exposure in male rats affects levels of gonadal steroids, mating frequency, and pregnancy outcome
- Dynamics of inflammatory reaction and oxidative stress across maternal serum, placenta and amniotic fluid in laboratory rats and the role played by genistein aglycone
- Cardiovascular-Pulmonary Interactions
- Local inhibition of carbonic anhydrase does not decrease sweat rate
- The standardized extract of Nigella sativa and its major ingredient, thymoquinone, ameliorates angiotensin II-induced hypertension in rats
- Correlation between the blood level of irisin and the severity of acute myocardial infarction in exercise-trained rats
- Oxidative Stress
- Zataria multiflora extract and carvacrol affect cardiotoxicity induced by Adriamycin in rat
- Attenuation of oxidative stress and hepatic damage by white butterfly (Clerodendrum volubile) leaves in streptozotocin-induced diabetes in rats
- Proline supplementation mitigates the early stage of liver injury in bile duct ligated rats
- Pravastatin attenuates testicular damage induced by doxorubicin – a stereological and histopatological study
- Metabolism
- Re-establishing normal diet following high fat-diet-induced obesity reverses the altered salivary composition in Wistar rats
- Phytotherapy
- In vivo analgesic effect of different extracts of Hopea odorata leaves in mice and in silico molecular docking and ADME/T property analysis of some isolated compounds from this plant
- Hepatoprotective activity of Tamarindus indica Linn stem bark ethanolic extract against hepatic damage induced by co-administration of antitubercular drugs isoniazid and rifampicin in Sprague Dawley rats
- Case Report
- Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis
Artikel in diesem Heft
- Frontmatter
- Reviews
- Immune response and inflammatory pathway of ulcerative colitis
- Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer
- Behavior and Neuroprotection
- Effect of caffeine on alcohol consumption and alcohol-induced conditioned place preference in rodents
- Reproduction
- Pubertal anabolic androgenic steroid exposure in male rats affects levels of gonadal steroids, mating frequency, and pregnancy outcome
- Dynamics of inflammatory reaction and oxidative stress across maternal serum, placenta and amniotic fluid in laboratory rats and the role played by genistein aglycone
- Cardiovascular-Pulmonary Interactions
- Local inhibition of carbonic anhydrase does not decrease sweat rate
- The standardized extract of Nigella sativa and its major ingredient, thymoquinone, ameliorates angiotensin II-induced hypertension in rats
- Correlation between the blood level of irisin and the severity of acute myocardial infarction in exercise-trained rats
- Oxidative Stress
- Zataria multiflora extract and carvacrol affect cardiotoxicity induced by Adriamycin in rat
- Attenuation of oxidative stress and hepatic damage by white butterfly (Clerodendrum volubile) leaves in streptozotocin-induced diabetes in rats
- Proline supplementation mitigates the early stage of liver injury in bile duct ligated rats
- Pravastatin attenuates testicular damage induced by doxorubicin – a stereological and histopatological study
- Metabolism
- Re-establishing normal diet following high fat-diet-induced obesity reverses the altered salivary composition in Wistar rats
- Phytotherapy
- In vivo analgesic effect of different extracts of Hopea odorata leaves in mice and in silico molecular docking and ADME/T property analysis of some isolated compounds from this plant
- Hepatoprotective activity of Tamarindus indica Linn stem bark ethanolic extract against hepatic damage induced by co-administration of antitubercular drugs isoniazid and rifampicin in Sprague Dawley rats
- Case Report
- Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis
