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Acute neurological conditions during pregnancy and their management: a review

  • Rubeena Maqbool , Mudasir Maqbool ORCID logo EMAIL logo , Mehrukh Zehravi and Irfat Ara
Published/Copyright: August 23, 2021

Abstract

Less vascular resistance, higher vascular permeability and improved cardiac output include anatomical and physiological changes related to pregnancy. These are needed to accommodate an increase in plasma volume and ensure significant organ infusion. Nevertheless, increases in oestrogen levels may lead to an increase in the risk of coagulation and thrombosis. Increased levels of progesterone increase the risk of thrombosis due to vasodilation, vascular stasis and edoema in these situations. The increased resistance in preeclampsia maternal systemic blood arteries can create high blood pressure that can interfere with blood flow in numerous organs (including liver, kidneys, brain and placenta). The risk of issues such as pulmonary edoema, placental abruption, pneumonia of aspiration, renal failure, hepatic failure and stroke in pregnant women is increased by Preeclampsia and eclampsia. Some peripheral neuropathies (carpal tunnel syndrome, peripheral facial palsy) and central neurological conditions (seizure, migraine, stroke, epilepsy) may become more common during pregnancy because of the exacerbation of the pre-existing neurologic condition or the onset of neurological disturbance caused by pregnancy physiological changes (such as headache or vascular disorders). During the three trimesters of pregnancy, neurological disorders are both peripheral and central. Therefore, an early and correct diagnosis is required to improve pregnancy care, treatment and perinatal outcomes. The aims of this paper are to identify, define and manage the most prevalent peripheral and centrally occurring neurological disorders in the pregnancy.


Corresponding author: Mudasir Maqbool, Research Scholar, Department of Pharmaceutical Sciences, University of Kashmir, Srinagar 190006, Jammu and Kashmir, India, E-mail:

Acknowledgement

Authors would like to thank all the authors whose work has been reviewed while preparing this manuscript.

  1. Research funding: None.

  2. Author contributions: All authors of this research paper have directly participated in the planning, execution & analysis of this study. All authors of this paper have read and approved the final version submitted. The content of this manuscript have not been copyrighted or published previously. The content of this manuscript is not now under consideration for publication elsewhere. The content of this manuscript will not be copyrighted, submitted, or published elsewhere, while acceptance by the journal is under consideration. There are no directly related manuscripts published or unpublished by any authors of this paper.

  3. Competing interests: None.

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Received: 2021-06-19
Accepted: 2021-07-14
Published Online: 2021-08-23

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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