Abstract
Less vascular resistance, higher vascular permeability and improved cardiac output include anatomical and physiological changes related to pregnancy. These are needed to accommodate an increase in plasma volume and ensure significant organ infusion. Nevertheless, increases in oestrogen levels may lead to an increase in the risk of coagulation and thrombosis. Increased levels of progesterone increase the risk of thrombosis due to vasodilation, vascular stasis and edoema in these situations. The increased resistance in preeclampsia maternal systemic blood arteries can create high blood pressure that can interfere with blood flow in numerous organs (including liver, kidneys, brain and placenta). The risk of issues such as pulmonary edoema, placental abruption, pneumonia of aspiration, renal failure, hepatic failure and stroke in pregnant women is increased by Preeclampsia and eclampsia. Some peripheral neuropathies (carpal tunnel syndrome, peripheral facial palsy) and central neurological conditions (seizure, migraine, stroke, epilepsy) may become more common during pregnancy because of the exacerbation of the pre-existing neurologic condition or the onset of neurological disturbance caused by pregnancy physiological changes (such as headache or vascular disorders). During the three trimesters of pregnancy, neurological disorders are both peripheral and central. Therefore, an early and correct diagnosis is required to improve pregnancy care, treatment and perinatal outcomes. The aims of this paper are to identify, define and manage the most prevalent peripheral and centrally occurring neurological disorders in the pregnancy.
Acknowledgement
Authors would like to thank all the authors whose work has been reviewed while preparing this manuscript.
-
Research funding: None.
-
Author contributions: All authors of this research paper have directly participated in the planning, execution & analysis of this study. All authors of this paper have read and approved the final version submitted. The content of this manuscript have not been copyrighted or published previously. The content of this manuscript is not now under consideration for publication elsewhere. The content of this manuscript will not be copyrighted, submitted, or published elsewhere, while acceptance by the journal is under consideration. There are no directly related manuscripts published or unpublished by any authors of this paper.
-
Competing interests: None.
References
1. Sacco, S, Ricci, S, Degan, D, Carolei, A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain 2012;13:177–89. https://doi.org/10.1007/s10194-012-0424-y.Search in Google Scholar PubMed PubMed Central
2. Prabhu, TRB. Cerebrovascular complications in pregnancy and puerperium. J Obstet Gynaecol India 2013;63:108–11. https://doi.org/10.1007/s13224-012-0251-8.Search in Google Scholar PubMed PubMed Central
3. Wang, Y, Hao, M, Sampson, S, Xia, J. Elective delivery versus expectant management for pre-eclampsia: a meta-analysis of RCTs. Arch Gynecol Obstet 2017;295:607–22. https://doi.org/10.1007/s00404-016-4281-9.Search in Google Scholar PubMed PubMed Central
4. Cipolla, MJ, Sweet, JG, Chan, S-L. Cerebral vascular adaptation to pregnancy and its role in the neurological complications of eclampsia. J Appl Physiol 2011;110:329–39. https://doi.org/10.1152/japplphysiol.01159.2010.Search in Google Scholar PubMed PubMed Central
5. Karlı, N, Baykan, B, Ertaş, M, Zarifoğlu, M, Siva, A, Saip, S, et al.. Impact of sex hormonal changes on tension-type headache and migraine: a cross-sectional population-based survey in 2,600 women. J Headache Pain 2012;13:557–65. https://doi.org/10.1007/s10194-012-0475-0.Search in Google Scholar PubMed PubMed Central
6. Kataoka, H, Miyoshi, T, Neki, R, Yoshimatsu, J, Ishibashi-Ueda, H, Iihara, K. Subarachnoid hemorrhage from intracranial aneurysms during pregnancy and the puerperium. Neurol Med -Chir 2013;53:549–54. https://doi.org/10.2176/nmc.53.549.Search in Google Scholar PubMed
7. Khosrawi, S, Maghrouri, R. The prevalence and severity of carpal tunnel syndrome during pregnancy. Adv Biomed Res 2012;1. https://doi.org/10.4103/2277-9175.100143.Search in Google Scholar PubMed PubMed Central
8. Meems, M, Truijens, SE, Spek, V, Visser, LH, Pop, VJ. Prevalence, course and determinants of carpal tunnel syndrome symptoms during pregnancy: a prospective study. BJOG An Int J Obstet Gynaecol 2015;122:1112–8. https://doi.org/10.1111/1471-0528.13360.Search in Google Scholar PubMed
9. Padua, L, Pasquale, AD, Pazzaglia, C, Liotta, GA, Librante, A, Mondelli, M. Systematic review of pregnancy‐related carpal tunnel syndrome. Muscle Nerve 2010;42:697–702. https://doi.org/10.1002/mus.21910.Search in Google Scholar PubMed
10. Storm, C, Wänman, A. Temporomandibular disorders, headaches, and cervical pain among females in a Sami population. Acta Odontol Scand 2006;64:319–25. https://doi.org/10.1080/00016350600801915.Search in Google Scholar PubMed
11. Pinhas-Hamiel, O, Frumin, K, Gabis, L, Mazor-Aronovich, K, Modan-Moses, D, Reichman, B, et al.. Headaches in overweight children and adolescents referred to a tertiary‐care center in Israel. Obesity 2008;16:659–63.10.1038/oby.2007.88Search in Google Scholar
12. Digre, KB. Headaches during pregnancy. Clin Obstet Gynecol 2013;56:317–29. https://doi.org/10.1097/grf.0b013e31828f25e6.Search in Google Scholar
13. Goadsby, PJ, Goldberg, J, Silberstein, SD. Migraine in pregnancy. BMJ 2008;336:1502–4. https://doi.org/10.1136/bmj.39559.675891.ad.Search in Google Scholar
14. Sances, G, Granella, F, Nappi, R, Fignon, A, Ghiotto, N, Polatti, F, et al.. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia 2003;23:197–205. https://doi.org/10.1046/j.1468-2982.2003.00480.x.Search in Google Scholar
15. Silberstein, SD. Migraine and pregnancy. Neurol Clin 1997;15:209–31. https://doi.org/10.1016/s0733-8619(05)70305-4.Search in Google Scholar
16. Martin, SR, Foley, MR. Approach to the pregnant patient with headache. Clin Obstet Gynecol 2005;48:2–11. https://doi.org/10.1097/01.grf.0000153208.93620.39.Search in Google Scholar PubMed
17. Silberstein, SD. Headaches in pregnancy. Neurol Clin 2004;22:727–56. https://doi.org/10.1016/j.ncl.2004.06.001.Search in Google Scholar PubMed
18. Revell, K, Morrish, P. Headaches in pregnancy. Obstet Gynaecol 2014;16:179–84. https://doi.org/10.1111/tog.12101.Search in Google Scholar
19. Jaigobin, C, Silver, FL. Stroke and pregnancy. Stroke 2000;31:2948–51. https://doi.org/10.1161/01.str.31.12.2948.Search in Google Scholar PubMed
20. Treadwell, S, Thanvi, B, Robinson, T. Stroke in pregnancy and the puerperium. Postgrad Med 2008;84:238–45. https://doi.org/10.1136/pgmj.2007.066167.Search in Google Scholar PubMed
21. James, AH, Bushnell, CD, Jamison, MG, Myers, ER. Incidence and risk factors for stroke in pregnancy and the puerperium. Obstet Gynecol 2005;106:509–16. https://doi.org/10.1097/01.aog.0000172428.78411.b0.Search in Google Scholar
22. Leffert, LR, Clancy, CR, Bateman, BT, Cox, M, Schulte, PJ, Smith, EE, et al.. Patient characteristics and outcomes after hemorrhagic stroke in pregnancy. Circ Cardiovasc Qual Outcomes 2015;8:S170–8. https://doi.org/10.1161/CIRCOUTCOMES.115.002242.Search in Google Scholar PubMed
23. Scott, CA, Bewley, S, Rudd, A, Spark, P, Kurinczuk, JJ, Brocklehurst, P, et al.. Incidence, risk factors, management, and outcomes of stroke in pregnancy. Obstet Gynecol 2012;120(2 Part 1):318–24. https://doi.org/10.1097/aog.0b013e31825f287c.Search in Google Scholar
24. Martin, P, Enevoldson, T, Humphrey, P. Causes of ischaemic stroke in the young. Postgrad Med 1997;73:8–16. https://doi.org/10.1136/pgmj.73.855.8.Search in Google Scholar PubMed PubMed Central
25. Bartkova, A, Sanak, D, Dostal, J, Herzig, R, Otruba, P, Vlachova, I, et al.. Acute ischaemic stroke in pregnancy: a severe complication of ovarian hyperstimulation syndrome. Neurol Sci 2008;29:463–6. https://doi.org/10.1007/s10072-008-1018-y.Search in Google Scholar PubMed
26. Maino, A, Siegerink, B, Algra, A, Martinelli, I, Peyvandi, F, Rosendaal, FR. Pregnancy loss and risk of ischaemic stroke and myocardial infarction. Br J Haematol 2016;174:302–9. https://doi.org/10.1111/bjh.14043.Search in Google Scholar PubMed
27. Kashkoush, AI, Ma, H, Agarwal, N, Panczykowski, D, Tonetti, D, Weiner, GM, et al.. Cerebral venous sinus thrombosis in pregnancy and puerperium: a pooled, systematic review. J Clin Neurosci 2017;39:9–15. https://doi.org/10.1016/j.jocn.2017.02.046.Search in Google Scholar PubMed
28. Mehraein, S, Ortwein, H, Busch, M, Weih, M, Einhäupl, K, Masuhr, F. Risk of recurrence of cerebral venous and sinus thrombosis during subsequent pregnancy and puerperium. J Neurol Neurosurg Psychiatr 2003;74:814–6. https://doi.org/10.1136/jnnp.74.6.814.Search in Google Scholar PubMed PubMed Central
29. Shah, M, Agarwal, N, Gala, N, Prestigiacomo, C, Gandhi, C. Management of dural venous sinus thrombosis in pregnancy. EJVES Extra 2014;27:e41–2. https://doi.org/10.1016/j.ejvsextra.2014.05.004.Search in Google Scholar
30. Zehravi, M, Maqbool, M, Ara, I. Polycystic ovary syndrome and reproductive health of women: a curious association. Int J Adolesc Med Health 2021. https://doi.org/10.1515/ijamh-2021-0031.Search in Google Scholar PubMed
31. Massey, EW, Guidon, AC. Peripheral neuropathies in pregnancy. CONTIN Lifelong Learn Neurol 2014;20:100–14. https://doi.org/10.1212/01.con.0000443839.02884.bb.Search in Google Scholar
32. Mabie, WC. Peripheral neuropathies during pregnancy. Clin Obstet Gynecol 2005;48:57–66. https://doi.org/10.1097/01.grf.0000153207.85996.4e.Search in Google Scholar
33. MASSEY, EW, CEFALO, RC. Neuropathies of pregnancy. Obstet Gynecol Surv 1979;34:489–92. https://doi.org/10.1097/00006254-197907010-00001.Search in Google Scholar
34. Klein, A.. Peripheral nerve disease in pregnancy. Clin Obstet Gynecol 2013;56:382–8. https://doi.org/10.1097/grf.0b013e31828f260e.Search in Google Scholar
35. Sax, TW, Rosenbaum, RB. Neuromuscular disorders in pregnancy. Muscle Nerve: Off J Am Assoc Electrodiagn Med 2006;34:559–71. https://doi.org/10.1002/mus.20661.Search in Google Scholar
36. Brooks, H, Christian, A, May, A. Pregnancy, anaesthesia and Guillain Barre syndrome. Anaesthesia 2000;55:894–8. https://doi.org/10.1046/j.1365-2044.2000.01367.x.Search in Google Scholar
37. Nelson, LH, McLEANJrWT. Management of Landry-Guillain-Barré syndrome in pregnancy. Obstet Gynecol 1985;65(3 Suppl):25S–9S.Search in Google Scholar
38. Pacheco, LD, Saad, AF, Hankins, GD, Chiosi, G, Saade, G. Guillain-Barré syndrome in pregnancy. Obstet Gynecol 2016;128:1105–10. https://doi.org/10.1097/aog.0000000000001716.Search in Google Scholar
39. Zafar, MSH, Naqash, MM, Bhat, TA, Malik, G. Guillain-barré syndrome in pregnancy: an unusual case. J Fam Med Prim Care 2013;2:90. https://doi.org/10.4103/2249-4863.109965.Search in Google Scholar
40. Djelmis, J, Sostarko, M, Mayer, D, Ivanisevic, M. Myasthenia gravis in pregnancy: report on 69 cases. Eur J Obstet Gynecol Reprod Biol 2002;104:21–5. https://doi.org/10.1016/s0301-2115(02)00051-9.Search in Google Scholar
41. Batocchi, AP, Majolini, L, Evoli, A, Lino, M, Minisci, C, Tonali, P. Course and treatment of myasthenia gravis during pregnancy. Neurology 1999;52. 447. https://doi.org/10.1212/wnl.52.3.447.Search in Google Scholar PubMed
42. Hoff, J, Daltveit, A, Gilhus, N. Myasthenia gravis in pregnancy and birth: identifying risk factors, optimising care. Eur J Neurol 2007;14:38–43. https://doi.org/10.1111/j.1468-1331.2006.01538.x.Search in Google Scholar
43. Ferrero, S, Esposito, F, Biamonti, M, Bentivoglio, G, Ragni, N. Myasthenia gravis during pregnancy. Expert Rev Neurother 2008;8:979–88. https://doi.org/10.1586/14737175.8.6.979.Search in Google Scholar
44. Téllez-Zenteno, JF, Hernández-Ronquillo, L, Salinas, V, Estanol, B, Da Silva, O. Myasthenia gravis and pregnancy: clinical implications and neonatal outcome. BMC Muscoskel Disord 2004;5:1–5. https://doi.org/10.1186/1471-2474-5-42.Search in Google Scholar
45. Mitchell, PJ, Bebbington, M. Myasthenia gravis in pregnancy. Obstet Gynecol 1992;80:178–81.10.1016/0020-7292(93)90171-RSearch in Google Scholar
46. Varner, M. Myasthenia gravis and pregnancy. Clin Obstet Gynecol 2013;56:372–81. https://doi.org/10.1097/grf.0b013e31828e92c0.Search in Google Scholar
47. Ferraz, Z, Parra, J, Areia, AL, Vasco, E, Moura, P. Acute onset neurological disorders during pregnancy: a literature review. Rev Bras Ginecol Obstet 2017;39:560–8. https://doi.org/10.1055/s-0037-1604058.Search in Google Scholar
48. Monini, S, Lazzarino, A, Iacolucci, C, Buffoni, A, Barbara, M. Epidemiology of Bell’s palsy in an Italian Health District: incidence and case-control study. Acta Otorhinolaryngol Ital 2010;30.Search in Google Scholar
49. Sherlie, VS, Varghese, A. ENT changes of pregnancy and its management. Indian J Otolaryngol Head Neck Surg 2014;66:6–9. https://doi.org/10.1007/s12070-011-0376-6.Search in Google Scholar
50. To, W, Cheung, R. Neurological disorders in pregnancy. Hong Kong Med J 1997.Search in Google Scholar
51. Aminoff, MJ. Neurological disorders and pregnancy. Am J Obstet Gynecol 1978;132:325–35. https://doi.org/10.1016/0002-9378(78)90902-x.Search in Google Scholar
52. Shehata, HA, Okosun, H. Neurological disorders in pregnancy. Curr Opin Obstet Gynecol 2004;16:117–22. https://doi.org/10.1097/00001703-200404000-00004.Search in Google Scholar PubMed
53. Berlit, P. Neurological disorders and pregnancy. Fortschr Neurol Psychiatr 2016;84:103–11. https://doi.org/10.1055/s-0041-108911.Search in Google Scholar PubMed
54. Pourrat, O, Neau, J, Pierre, F. Bell’s palsy in pregnancy: underlying HELLP syndrome or pre-eclampsia? Obstet Med 2013;6:132–3. https://doi.org/10.1258/om.2012.110093.Search in Google Scholar
55. Juan, Y-C, Au, H-K, Hsu, J-J, Ma, P-C, Liu, W-M, Jeng, C-J. Bell palsy and preeclampsia superimposed on chronic hypertension. Taiwan J Obstet Gynecol 2010;49:223–4. https://doi.org/10.1016/s1028-4559(10)60049-6.Search in Google Scholar
56. Richards, A, Graham, D, Bullock, R. Clinicopathological study of neurological complications due to hypertensive disorders of pregnancy. J Neurol Neurosurg Psychiatr 1988;51:416–21. https://doi.org/10.1136/jnnp.51.3.416.Search in Google Scholar PubMed PubMed Central
57. Haider, B, von Oertzen, J. Neurological disorders. Best Pract Res Clin Obstet Gynaecol 2013;27:867–75. https://doi.org/10.1016/j.bpobgyn.2013.07.007.Search in Google Scholar PubMed
58. Mao-Draayer, Y, Thiel, S, Mills, EA, Chitnis, T, Fabian, M, Sand, IK, et al.. Neuromyelitis optica spectrum disorders and pregnancy: therapeutic considerations. Nat Rev Neurol 2020;16:154–70. https://doi.org/10.1038/s41582-020-0313-y.Search in Google Scholar PubMed
59. Renukesh, S, Rai, L. Neurological disorders complicating pregnancy-focus on obstetric outcome. J Clin Diagn Res: J Clin Diagn Res 2016;10:QC06. https://doi.org/10.7860/JCDR/2016/19839.8955.Search in Google Scholar PubMed PubMed Central
60. Maqbool, M, Khan, M. Hypertension and Pregnancy: an important issue. PharmaTutor 2019;7:71–8.Search in Google Scholar
61. Soldin, OP, Dahlin, J, O’Mara, DM. Triptans in pregnancy. Ther Drug Monit 2008;30:5. https://doi.org/10.1097/ftd.0b013e318162c89b.Search in Google Scholar PubMed PubMed Central
62. Nezvalová-Henriksen, K, Spigset, O, Nordeng, H. Triptan safety during pregnancy: a Norwegian population registry study. Eur J Epidemiol 2013;28:759–69. https://doi.org/10.1007/s10654-013-9831-x.Search in Google Scholar PubMed
63. Maqbool, M, Dar, MA, Gani, I, Mir, SA, Khan, M, Bhat, AU. Maternal health and nutrition in pregnancy: an insight. World J Pharm Pharmaceut Sci 2019;8:450–9.Search in Google Scholar
64. Khan, M, Maqbool, M. About authors. Hypertension 2019;17.Search in Google Scholar
65. Jarvis, S, Nelson-Piercy, C. Management of nausea and vomiting in pregnancy. BMJ 2011:342. https://doi.org/10.1136/bmj.d3606.Search in Google Scholar PubMed
66. Asker, C, Wikner, BN, Källén, B. Use of antiemetic drugs during pregnancy in Sweden. Eur J Clin Pharmacol 2005;61:899–906. https://doi.org/10.1007/s00228-005-0055-1.Search in Google Scholar PubMed
67. Gadsby, R, Barnie-Adshead, T, Sykes, C. Why won’t doctors prescribe antiemetics in pregnancy? BMJ 2011:343. https://doi.org/10.1136/bmj.d4387.Search in Google Scholar PubMed
68. Minagar, A. Neurological disorders and pregnancy. Elsevier; 2010.Search in Google Scholar
69. El-Refai, NAE-R. Anesthetic management for parturients with neurological disorders. Anesth Essays Res 2013;7:147. https://doi.org/10.4103/0259-1162.118940.Search in Google Scholar PubMed PubMed Central
70. Donaldson, JO. Neurological disorders. London, UK: Blackwell Science Ltd; 2002.10.1002/9780470752371.ch15Search in Google Scholar
71. Townsend, R, O’Brien, P, Khalil, A. Current best practice in the management of hypertensive disorders in pregnancy. Integrated Blood Pres Contr 2016;9:79. https://doi.org/10.2147/IBPC.S77344.Search in Google Scholar PubMed PubMed Central
72. Coyle, PK. Management of women with multiple sclerosis through pregnancy and after childbirth. Ther Adv Neurol Disord 2016;9:198–210. https://doi.org/10.1177/1756285616631897.Search in Google Scholar PubMed PubMed Central
73. Lowe, SA, Brown, MA, Dekker, GA, Gatt, S, McLintock, CK, McMAHON, LP, et al.. Guidelines for the management of hypertensive disorders of pregnancy 2008. Aust N Z J Obstet Gynaecol 2009;49:242–6. https://doi.org/10.1111/j.1479-828X.2009.01003.x.Search in Google Scholar PubMed
74. Kaplan, TB. Management of demyelinating disorders in pregnancy. Neurol Clin 2019;37:17–30. https://doi.org/10.1016/j.ncl.2018.09.007.Search in Google Scholar PubMed
© 2021 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Reviews
- Effective strategies to improve health worker performance in delivering adolescent-friendly sexual and reproductive health services
- Sleep disturbance and depression in adolescence: an integrative review of literature
- Multiple behavioural risk factors of non-communicable diseases among adolescents in four Caribbean countries: prevalence and correlates
- The post 16 gap: how do young people conceptualise PE? An exploration of the barriers to participation in physical education, physical activity and sport in senior school pupils
- The effect of cognitive behavior therapy on body image and self-esteem in female adolescents: a systematic review and meta-analysis
- Polycystic ovary syndrome and reproductive health of women: a curious association
- Correlation between obesity, gestational diabetes mellitus, and pregnancy outcomes: an overview
- Mindfulness and eudaimonic well-being: the mediating roles of rumination and emotion dysregulation
- Acute neurological conditions during pregnancy and their management: a review
- Depression and anxiety in women with polycystic ovarian syndrome: a literature survey
- Significance of sugar intake in young adults: a review
- Original Articles
- Prevalence and factors associated with smoking among Tunisian secondary school-adolescents
- Physical fitness and its association with overweight among early adolescents in Puducherry, Southern India
- Knowledge and awareness of individual sickle cell genotype among adolescents in a unity school in Southeast, Nigeria: a cross-sectional study
- Popular water pipe smoking, medical sciences students' awareness, perceptions, and motivations
- Investigation E-health literacy and correlates factors among Alborz medical sciences students: a cross sectional study
- Risk of eating disorders in university students: an international study in Hungary, Poland and Ukraine
- Prevalence and associated factors of oral and hand hygiene behaviour among adolescents in six Southeast Asian countries
- Assessment of academic performance of licensed athletes
- Gender-based differences in risk-taking behaviors among high school students in Southeast Iran
- Experience of sexual and gender minority youth when accessing health care in Turkey
- Use of modern contraceptives among advanced-level secondary school girls in the Rukwa Region, Tanzania, 2018
- The effect of poetry reading on self-concept of primary adolescents
- The association of acne and menstrual symptoms among young women (18–25 years) in Egypt: a population-based cross-sectional study
- Sexual risk behaviors and influencing factors among Muslim adolescents on southern border of Thailand
- Not just studies, but fitness can also get you the intelligence and the grades!!
- Effectiveness of a school-based intervention in Guatemala to increase knowledge of sexual and reproductive health
- Stressful life events and depressive symptoms among adolescents in Malaysia: the mediating role of maladaptive cognitive schema
- Sexual risk behaviour and its correlates among adolescents in Indonesia, Laos, Thailand and Timor-Leste: results from national school surveys in 2015
- Utilization rate and factors influencing the use of HIV counseling and testing services among young females: a community-based study from Nigeria
- Pattern and quitting of tobacco smoking among Egyptian university students
- Association between parents and peer attachment with health locus of control: a cross-sectional study among Iranian adolescents
- Body dissatisfaction and its association with domains of physical activity and of sedentary behavior in a sample of 15,632 adolescents
- Effect of Bhramari pranayama practice on simple reaction time in healthy adolescents – a randomized control trial
- Short Communications
- Survey of school nurses’ experiences of providing counselling on sexual orientation to high school students in Japan
- Prevalence and correlates of fruit and vegetable consumption among adolescents in Laos
Articles in the same Issue
- Frontmatter
- Reviews
- Effective strategies to improve health worker performance in delivering adolescent-friendly sexual and reproductive health services
- Sleep disturbance and depression in adolescence: an integrative review of literature
- Multiple behavioural risk factors of non-communicable diseases among adolescents in four Caribbean countries: prevalence and correlates
- The post 16 gap: how do young people conceptualise PE? An exploration of the barriers to participation in physical education, physical activity and sport in senior school pupils
- The effect of cognitive behavior therapy on body image and self-esteem in female adolescents: a systematic review and meta-analysis
- Polycystic ovary syndrome and reproductive health of women: a curious association
- Correlation between obesity, gestational diabetes mellitus, and pregnancy outcomes: an overview
- Mindfulness and eudaimonic well-being: the mediating roles of rumination and emotion dysregulation
- Acute neurological conditions during pregnancy and their management: a review
- Depression and anxiety in women with polycystic ovarian syndrome: a literature survey
- Significance of sugar intake in young adults: a review
- Original Articles
- Prevalence and factors associated with smoking among Tunisian secondary school-adolescents
- Physical fitness and its association with overweight among early adolescents in Puducherry, Southern India
- Knowledge and awareness of individual sickle cell genotype among adolescents in a unity school in Southeast, Nigeria: a cross-sectional study
- Popular water pipe smoking, medical sciences students' awareness, perceptions, and motivations
- Investigation E-health literacy and correlates factors among Alborz medical sciences students: a cross sectional study
- Risk of eating disorders in university students: an international study in Hungary, Poland and Ukraine
- Prevalence and associated factors of oral and hand hygiene behaviour among adolescents in six Southeast Asian countries
- Assessment of academic performance of licensed athletes
- Gender-based differences in risk-taking behaviors among high school students in Southeast Iran
- Experience of sexual and gender minority youth when accessing health care in Turkey
- Use of modern contraceptives among advanced-level secondary school girls in the Rukwa Region, Tanzania, 2018
- The effect of poetry reading on self-concept of primary adolescents
- The association of acne and menstrual symptoms among young women (18–25 years) in Egypt: a population-based cross-sectional study
- Sexual risk behaviors and influencing factors among Muslim adolescents on southern border of Thailand
- Not just studies, but fitness can also get you the intelligence and the grades!!
- Effectiveness of a school-based intervention in Guatemala to increase knowledge of sexual and reproductive health
- Stressful life events and depressive symptoms among adolescents in Malaysia: the mediating role of maladaptive cognitive schema
- Sexual risk behaviour and its correlates among adolescents in Indonesia, Laos, Thailand and Timor-Leste: results from national school surveys in 2015
- Utilization rate and factors influencing the use of HIV counseling and testing services among young females: a community-based study from Nigeria
- Pattern and quitting of tobacco smoking among Egyptian university students
- Association between parents and peer attachment with health locus of control: a cross-sectional study among Iranian adolescents
- Body dissatisfaction and its association with domains of physical activity and of sedentary behavior in a sample of 15,632 adolescents
- Effect of Bhramari pranayama practice on simple reaction time in healthy adolescents – a randomized control trial
- Short Communications
- Survey of school nurses’ experiences of providing counselling on sexual orientation to high school students in Japan
- Prevalence and correlates of fruit and vegetable consumption among adolescents in Laos