Risk factors and inflammatory markers in acute coronary syndrome-ST elevation myocardial infarction (STEMI)
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Thirumurthi Karthikeyan
,
Mani Raja
,
Devarajan Radha
,
Archana Gaur T
,
Jeganathan Geetha
und
Varatharajan Sakthivadivel
Abstract
Objectives
The increasing prevalence of coronary artery disease [CAD] poses worrying statistics. Atherosclerosis of coronary vessels is the main culprit for the spectrum of CAD especially acute coronary syndrome. Atherosclerosis is regarded as a consequence of inflammatory changes in the coronaries. Our study aimed to assess the role of risk factors and inflammatory markers with acute ST-elevation myocardial infarction [STEMI].
Methods
100 patients with ST-elevation Myocardial infarction [STEMI] and 100 age and sex matched controls were included in the study. A history of risk factors like smoking, hypertension, diabetes and hypertension was noted. A venous blood sample was obtained for analysis of inflammatory markers. The data thus obtained was statistically analyzed.
Results
The cases had a significant number of risk factors such as smoking, hypertension, and diabetes mellitus, previous history of CAD, increased body mass index [BMI], and raised high sensitive C-reactive protein [hs-CRP]. Patients with anterior myocardial infarction were older and had hypertension and diabetes mellitus. Patients with inferior myocardial infarction had high BMI, raised erythrocyte sedimentation rate [ESR] and alcoholism. Smokers, patients with diabetes mellitus, high total cholesterol, Low-density lipoprotein [LDL] cholesterol, and hs-CRP were more prone to complications.
Conclusions
Patients with a greater number of risk factors and raised inflammatory markers were at high risk of STEMI and its complications. An approach to control the modifiable risk factors like obesity and lifestyle changes can reduce the disease burden.
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Research funding: None declared.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: Informed consent was obtained from all individuals included in this study.
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Ethical approval: Obtained from Institute ethical committee.
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© 2023 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Letter to the Editor
- The role of gut microbiota in etiopathogenesis of long COVID syndrome
- Original Articles
- Risk factors and inflammatory markers in acute coronary syndrome-ST elevation myocardial infarction (STEMI)
- Association of pro-inflammatory cytokines, inflammatory proteins with atherosclerosis index in obese male subjects
- Exploration of meteorin-like peptide (metrnl) predictors in type 2 diabetic patients: the potential role of irisin, and other biochemical parameters
- Distinct urinary progesterone metabolite profiles during the luteal phase
- Promoter methylation levels of RASSF1 and ATIC genes are associated with lung cancer in Iranian patients
- Population status of selenium in Colombia and associated factors: a cross-sectional study
- Bambusa vulgaris leaves reverse mitochondria dysfunction in diabetic rats through modulation of mitochondria biogenic genes
- Increased expression of androgen receptor and PSA genes in LNCaP (prostate cancer) cell line due to high concentrations of EGCG, an active ingredient in green tea
- The effects of endurance exercise and metformin on memory impairment caused by diabetes
- Exercise modulation in inflammation and metabolic hormonal disorders of COVID-19 to decrease risk factors in coronary heart disease
- The effect of co-administration of artemisinin and N-acetyl cysteine on antioxidant status, spermatological parameters and histopathology of testis in adult male mice
- Case Report
- Unilateral ovarian agenesis with ipsilateral tubal presence – report of a case
- Review Articles
- Brown adipose tissue as an endocrine organ: updates on the emerging role of batokines
- Zuranolone and its role in treating major depressive disorder: a narrative review
Artikel in diesem Heft
- Frontmatter
- Letter to the Editor
- The role of gut microbiota in etiopathogenesis of long COVID syndrome
- Original Articles
- Risk factors and inflammatory markers in acute coronary syndrome-ST elevation myocardial infarction (STEMI)
- Association of pro-inflammatory cytokines, inflammatory proteins with atherosclerosis index in obese male subjects
- Exploration of meteorin-like peptide (metrnl) predictors in type 2 diabetic patients: the potential role of irisin, and other biochemical parameters
- Distinct urinary progesterone metabolite profiles during the luteal phase
- Promoter methylation levels of RASSF1 and ATIC genes are associated with lung cancer in Iranian patients
- Population status of selenium in Colombia and associated factors: a cross-sectional study
- Bambusa vulgaris leaves reverse mitochondria dysfunction in diabetic rats through modulation of mitochondria biogenic genes
- Increased expression of androgen receptor and PSA genes in LNCaP (prostate cancer) cell line due to high concentrations of EGCG, an active ingredient in green tea
- The effects of endurance exercise and metformin on memory impairment caused by diabetes
- Exercise modulation in inflammation and metabolic hormonal disorders of COVID-19 to decrease risk factors in coronary heart disease
- The effect of co-administration of artemisinin and N-acetyl cysteine on antioxidant status, spermatological parameters and histopathology of testis in adult male mice
- Case Report
- Unilateral ovarian agenesis with ipsilateral tubal presence – report of a case
- Review Articles
- Brown adipose tissue as an endocrine organ: updates on the emerging role of batokines
- Zuranolone and its role in treating major depressive disorder: a narrative review
