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Engineered nanomaterials and human health: Part 2. Applications and nanotoxicology (IUPAC Technical Report)

Published/Copyright: October 29, 2018
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Chemistry International
From the journal Chemistry International Volume 40 Issue 4

Vladimir Gubala, Linda J. Johnston, Harald F. Krug, Colin J. Moore, Christopher K. Ober, Michael Schwenk, and Michel Vert

Pure and Applied Chemistry 2018Volume 90, Issue 8, pp. 1325–1356

Research on engineered nanomaterials (ENM) has progressed rapidly from the very early stages of studying their unique, size-dependent physicochemical properties and commercial exploration to the development of products that influence our everyday lives. We have previously reviewed various methods for synthesis, surface functionalization, and analytical characterization of ENM in a publication titled “Engineered Nanomaterials: Preparation, Functionalization and Characterization.” In this second, inter-linked document, we first provide an overview of important applications of ENM in products relevant to human healthcare and consumer goods, such as food, textiles, and cosmetics. We then highlight the challenges for the design and development of new ENM for bio-applications, particularly in the rapidly developing nanomedicine sector. The second part of this document is dedicated to nanotoxicology studies of ENM in consumer products. We describe the various biological targets where toxicity may occur, summarize the four nanotoxicology principles, and discuss the need for careful consideration of the biodistribution, degradation, and elimination routes of nanosized materials before they can be safely used. Finally, we review expert opinions on the risk, regulation, and ethical aspects of using engineered nanomaterials in applications that may have direct or indirect impact on human health or our environment.

https://doi.org/10.1515/pac-2017-0102

Online erschienen: 2018-10-29
Erschienen im Druck: 2018-10-01

©2018 IUPAC & De Gruyter. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. For more information, please visit: http://creativecommons.org/licenses/by-nc-nd/4.0/

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https://doi.org/10.1515/ci-2018-0425

Articles in the same Issue

  1. Masthead - Full issue pdf
  2. Vice President’s Column
  3. Towards 2019 and the Future
  4. Features
  5. Chemistry of Small Spaces
  6. Chemistry for the Future Solvay Prize
  7. IUPAC in the (real) clouds
  8. Chemistry: The Driving Force for Emerging Technologies
  9. Preprints and Scholarly Communication in Chemistry: A look at ChemRxiv
  10. IUPAC Wire
  11. IUPAC Elections for the 2020–2021 Term
  12. Mirabbos Hojamberdiev is awarded the 2018 IUPAC Chemrawn VII Prize for Green Chemistry
  13. Standard Atomic Weights of 14 Chemical Elements Revised
  14. 2019 IUPAC-Solvay International Award for Young Chemists—call for applicants
  15. Periodic Table of Younger Chemists Revealed
  16. 2018 Hall of Fame Inductees Announced— ACS Division of Medicinal Chemistry
  17. IUPAC seeks Expressions of Intent to host 2025 General Assembly and World Chemistry Congress
  18. Stamps International
  19. Oganesson, Where Art Thou?
  20. Project Place
  21. Safety of Engineered Nanomaterials
  22. Realisation of a Unified pH Scale
  23. Successful Drug Discovery
  24. ILLIAS: An epic journey towards the database on liquid-liquid equilibria in systems containing ionic liquids
  25. InChI Open Education Resource
  26. Microwave induced combustion—critical evaluation and new applications
  27. Multiple Uses of Chemicals—Website updates and translations into OPCW official languages
  28. IUPAC COCI Safety Training Program—Latin America, STP Associates Training
  29. Making an imPACt
  30. Nomenclature for boranes and related species
  31. Making an imPACt
  32. Engineered nanomaterials and human health: Part 1. Preparation, functionalization and charact-erization (IUPAC Technical Report)
  33. Engineered nanomaterials and human health: Part 2. Applications and nanotoxicology (IUPAC Technical Report)
  34. The ongoing challenge of novel psychoactive drugs of abuse. Part I. Synthetic cannabinoids (IUPAC Technical Report)
  35. Nomenclature of flavonoids (IUPAC Recommendations 2017)
  36. Standard reporting of Electrical Energy per Order (EEO) for UV/H2O2 Reactors (IUPAC Technical Report)
  37. Innovative Technologies for Chemical Security
  38. Conference Call
  39. IUPAC Postgraduate Summer School on Green Chemistry
  40. Polymers: Design, Function, and Application
  41. Polymers and Organic Materials for Electronics and Photonics: Science for Applications
  42. Chemistry for Beauty and Health
  43. From Thailand to Spain
  44. Where 2B & Y
  45. Science as a Human Right: International Science Center and Science Museum Day (ISCSMD)
  46. Mendeleev 150
  47. Solution Chemistry of Technology Critical Elements
  48. Mark Your Calendar
  49. Footnotes
  50. Index 2018
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