Startseite Using nutritional and oxidative stress to increase content of healthbeneficial fatty acids in oleaginous and non-oleaginous yeasts
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Using nutritional and oxidative stress to increase content of healthbeneficial fatty acids in oleaginous and non-oleaginous yeasts

  • Karolína Pádrová EMAIL logo , Irena Kolouchová , Tomáš Řezanka und Alena Čejková
Veröffentlicht/Copyright: 23. Mai 2016
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Chemical Papers
Aus der Zeitschrift Chemical Papers Band 70 Heft 10

Abstract

Yeast responses to stress conditions include an increase in lipid content and concomitant changes in content of saturated and unsaturated fatty acids. Some fatty acids are among the dietetically important fatty acids and new possibilities are sought for their biotechnological production in addition to those already exploited from marine organisms, nuts and other sources. The possibility of the production of palmitoleic and linoleic acids resulting from new approaches to traditional biotechnologically useful yeast species (Kluyveromyces polysporus, Saccharomyces cerevisiae, Torulospora delbrueckii) and species capable of high accumulation of lipids (Rhodotorula glutinis, Trichosporon cutaneum, Candida sp., Yarrowia lipolytica) was explored. The most promising was the combination of two stress factors: limitation of N-sources (C/N mass ratio of 70 : 1) and oxidative stress induced by zero- valent iron nanoparticles. These conditions were conducive to the production of palmitoleic acid commonly used in cosmetics and medicine and ω-6-linoleic acid, a precursor of thromboxanes, prostaglandins and leucotrienes. The yield of these two fatty acids in T. cutaneum was more than 500 mg g−1 (dry mass) and in Candida sp. more than 600 mg g−1 (dry mass).

Key words: oleaginous yeasts; non-oleaginous yeasts; microbiallipids; unsaturated fatty acids; zerovalent iron

Acknowledgements

This study received financial support from GACR 14-00227S and for specific university research (MSMT no. 20/2015).

Supplementary data

The supplementary data associated with this article (Using nutritional and oxidative stress to increase content of health-beneficial fatty acids in oleaginous and non-oleaginous yeasts) can be found in the online version of this paper (DOI: 10.1515/chempap-20160060).

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Received: 2016-1-4
Revised: 2016-2-18
Accepted: 2016-2-22
Published Online: 2016-5-23
Published in Print: 2016-10-1

© 2016 Institute of Chemistry, Slovak Academy of Sciences

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  19. Original Paper
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https://doi.org/10.1515/chempap-2016-0060
Schlagwörter für diesen Artikel
oleaginous yeasts; non-oleaginous yeasts; microbiallipids; unsaturated fatty acids; zerovalent iron

Artikel in diesem Heft

  1. Original Paper
  2. Simultaneous analysis of polar and non-polar components of cell membrane phospholipids by GC-MS
  3. Original Paper
  4. Cloud point extraction of disulfiram for its HPLC-MS/MS determination in synthetic urine
  5. Original Paper
  6. Revealing the seed proteome of the health benefitting grain amaranth (Amaranthus cruentus L.)
  7. Original Paper
  8. Possible role of hydrolytic enzymes (Sap, Kex2) in Candida albicans response to aromatic compounds bearing a sulfone moiety
  9. Original Paper
  10. Using nutritional and oxidative stress to increase content of healthbeneficial fatty acids in oleaginous and non-oleaginous yeasts
  11. Original Paper
  12. Fatty acids and amino acids of entomopathogenic fungus Conidiobolus coronatus grown on minimal and rich media
  13. Original Paper
  14. Promotional effect of cobalt addition on catalytic performance of Ce0.5Zr0.5O2 mixed oxide for diesel soot combustion
  15. Original Paper
  16. Microwave-assisted continuous reactive distillation process for preparation of ethyl acetate
  17. Original Paper
  18. Wall-retardation effects on particles settling through non-Newtonian fluids in parallel plates
  19. Original Paper
  20. Microwave-assisted decomposition of fgd gypsum in the presence of magnetite and anthracite
  21. Original Paper
  22. Effect of PHB on the properties of biodegradable PLA blends
  23. Original Paper
  24. Thiophene-free diphenyl-amino-stilbene-diketo-pyrrolo-pyrrole derivatives as donors for organic bulk heterojunction solar cells
  25. Short Communication
  26. UV-induced reduction of Ag+ by diazene sulphonates: new method of metallisation of surfaces
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