Abstract
Many countries are considering the expansion of their newborn bloodspot screening programmes. Whereas some countries screen for very few conditions, others are planning to screen for dozens. While advances in technology may facilitate this expansion, they must not lead it at the expense of considerations of the possible harms of this expansion. This article reviews some of the potential disbenefits of this expansion and outlines the ethical issues that should be considered.
Keywords: benefits; ethics; genetic screening; harms; newborn bloodspot screening; screening criteria
Received: 2011-6-16
Accepted: 2011-9-30
Published Online: 2011-10-28
Published in Print: 2012-06-01
©2012 by Walter de Gruyter Berlin Boston
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Keywords for this article
benefits;
ethics;
genetic screening;
harms;
newborn bloodspot screening;
screening criteria
Articles in the same Issue
- Masthead
- Masthead
- Editorial
- Laboratory maternal-fetal medicine: challenges and perspectives
- Reviews
- Candidate biochemical markers for screening of pre-eclampsia in early pregnancy
- Linking preeclampsia and cardiovascular disease later in life
- Mini Reviews
- Fetal nucleic acids in maternal blood: the promises
- Ethical aspects of the expansion of neonatal screening programme due to technological advances
- Prenatal screening for trisomy 21: recent advances and guidelines
- Ultrasound markers for the detection of women at risk of developing pre-eclampsia
- Are biological markers relevant for the diagnosis and the prognosis of preterm premature rupture of membranes (PPROM)?
- Genetics and Molecular Diagnostics
- Study of FTMT and ABCA4 genes in a patient affected by age-related macular degeneration: identification and analysis of new mutations
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- Unlabeled-probe high-resolution melting to detect KRAS codon 12 and 13 mutations in pancreatic adenocarcinoma tissues
- General Clinical Chemistry and Laboratory Medicine
- Volume, rates, source and types of add-on pathology test requests across five hospitals
- Schizophrenia is associated with increased levels of serum Fas and FasL
- Comparison between capillary, venous and arterial levels of protein S100B in patients with severe brain pathology
- Changes of serum adiponectin and soluble intercellular adhesion molecule-1 concentrations after smoking cessation
- Lack of consistency between two commercial ELISAs and against an in-house ELISA for the detection of CD36 in human plasma
- Comparison of a commercial urinary neopterin radioimmunoassay with high performance liquid chromatography
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- Comments on a performance evaluation of cartridge-type blood gas analyzers. Reply
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