Startseite Extending laboratory automation to the wards: effect of an innovative pneumatic tube system on diagnostic samples and transport time
Artikel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Extending laboratory automation to the wards: effect of an innovative pneumatic tube system on diagnostic samples and transport time

  • Juliane Suchsland , Theresa Winter , Anne Greiser , Thomas Streichert , Benjamin Otto , Julia Mayerle , Sören Runge , Anders Kallner , Matthias Nauck und Astrid Petersmann EMAIL logo
Veröffentlicht/Copyright: 30. Juni 2016
Veröffentlichen auch Sie bei De Gruyter Brill

Abstract

Background:

The innovative pneumatic tube system (iPTS) transports one sample at a time without the use of cartridges and allows rapid sending of samples directly into the bulk loader of a laboratory automation system (LAS). We investigated effects of the iPTS on samples and turn-around time (TAT).

Methods:

During transport, a mini data logger recorded the accelerations in three dimensions and reported them in arbitrary area under the curve (AUC) units. In addition representative quantities of clinical chemistry, hematology and coagulation were measured and compared in 20 blood sample pairs transported by iPTS and courier.

Results:

Samples transported by iPTS were brought to the laboratory (300 m) within 30 s without adverse effects on the samples. The information retrieved from the data logger showed a median AUC of 7 and 310 arbitrary units for courier and iPTS transport, respectively. This is considerably below the reported limit for noticeable hemolysis of 500 arbitrary units.

Conclusions:

iPTS reduces TAT by reducing the hands-on time and a fast transport. No differences in the measurement results were found for any of the investigated 36 analytes between courier and iPTS transport. Based on these findings the iPTS was cleared for clinical use in our hospital.


Corresponding author: Dr. med. Dipl. Biol. Astrid Petersmann, Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Str., 17475 Greifswald, Germany, Phone: +49-3834-86-5670
aPresent address: Eppendorf AG, Hamburg, Germany.
  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

References

1. Armbruster DA, Overcash DR, Reyes J. Clinical chemistry laboratory automation in the 21st century – Amat Victoria curam (Victory loves careful preparation). Clin Biochem Rev 2014;35:143–53.Suche in Google Scholar

2. Fernandes CM, Worster A, Eva K, Hill S, McCallum C. Pneumatic tube delivery system for blood samples reduces turnaround times without affecting sample quality. J Emerg Nurs 2006;32:139–43.10.1016/j.jen.2005.11.013Suche in Google Scholar PubMed

3. Lippi G, Plebani M, Favaloro EJ. Technological advances in the hemostasis laboratory. Semin Thromb Hemost 2014;40:178–85.10.1055/s-0033-1364206Suche in Google Scholar PubMed

4. Al-Riyami AZ, Al-Khabori M, Al-Hadhrami RM, Al-Azwani IS, Davis HM, Al-Farsi KS, et al. The pneumatic tube system does not affect complete blood count results; a validation study at a tertiary care hospital. Int J Lab Hematol 2014;36:514–20.10.1111/ijlh.12180Suche in Google Scholar PubMed

5. Gossez M, Poitevin-Later F, Demaret J, Jallades L, Venet F, Malcus C, et al. Effect of pneumatic tube transport on T lymphocyte subsets analysis. Cytometry B Clin Cytom 2015;88:371–4.10.1002/cyto.b.21231Suche in Google Scholar PubMed

6. Pragay DA, Edwards L, Toppin M, Palmer RR, Chilcote ME. Evaluation of an improved pneumatic-tube system suitable for transportation of blood specimens. Clin Chem 1974;20:57–60.10.1093/clinchem/20.1.57Suche in Google Scholar

7. Ellis G. An episode of increased hemolysis due to a defective pneumatic air tube delivery system. Clin Biochem 2009;42:1265–9.10.1016/j.clinbiochem.2009.05.002Suche in Google Scholar PubMed

8. Strubi-Vuillaume I, Carlier V, Obeuf C, Vasseur F, Maury J-C, Maboudou P, et al. Gentle blood aspiration and tube cushioning reduce pneumatic tube system interference in lactate dehydrogenase assays. Ann Clin Biochem 2016;53(Pt 2):295–7.10.1177/0004563215586600Suche in Google Scholar PubMed

9. Medical laboratories – Requirements for quality and competence (ISO 15189:2012, Corrected version 2014-08-15); German version EN ISO 15189:2012.Suche in Google Scholar

10. Revision of the “Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations – Rili-BAEK” (unauthorized translation). J Lab Med 2015;39:26–69.10.1515/labmed-2014-0046Suche in Google Scholar

11. Streichert T, Otto B, Schnabel C, Nordholt G, Haddad M, Maric M, et al. Determination of hemolysis thresholds by the use of data loggers in pneumatic tube systems. Clin Chem 2011;57:1390–7.10.1373/clinchem.2011.167932Suche in Google Scholar PubMed

12. Mensel B, Wenzel U, Roser M, Ludemann J, Nauck M. Considerably reduced centrifugation time without increased hemolysis: evaluation of the new BD Vacutainer SSTTMII Advance. Clin Chem 2007;53:794–5.10.1373/clinchem.2006.079582Suche in Google Scholar PubMed

13. Goswami B, Singh B, Chawla R, Gupta VK, Mallika V. Turn around time (TAT) as a benchmark of laboratory performance. Indian J Clin Biochem 2010;25:376–9.10.1007/s12291-010-0056-4Suche in Google Scholar PubMed PubMed Central

14. Wenham PR, Hanson T, Ashby JP. Interference in spectrophotometric analysis of cerebrospinal fluid by haemolysis induced by transport through a pneumatic tube system. Ann Clin Biochem 2001;38(Pt 4):371–5.10.1258/0004563011900687Suche in Google Scholar PubMed

15. Kratz A, Salem RO, van Cott EM. Effects of a pneumatic tube system on routine and novel hematology and coagulation parameters in healthy volunteers. Arch Pathol Lab Med 2007;131:293–6.10.5858/2007-131-293-EOAPTSSuche in Google Scholar PubMed

16. Evliyaoglu O, Toprak G, Tekin A, Basarali MK, Kilinc C, Colpan L. Effect of pneumatic tube delivery system rate and distance on hemolysis of blood specimens. J Clin Lab Anal 2012;26:66–9.10.1002/jcla.21484Suche in Google Scholar PubMed PubMed Central

17. Hansen Rohrpost. Available at: URL:http://www.hansen-rohrpost.de/rohrmaterial/pvc-rohrpostfahrrohr/. Accessed: 20 Mar 2015.Suche in Google Scholar

Received: 2016-5-1
Accepted: 2016-5-30
Published Online: 2016-6-30
Published in Print: 2017-2-1

©2017 Walter de Gruyter GmbH, Berlin/Boston

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Commutable samples with assigned target concentrations may help us harmonise general chemistry results
  4. Reviews
  5. Performance of point-of-care HbA1c test devices: implications for use in clinical practice – a systematic review and meta-analysis
  6. Cardiac troponins and mortality in type 1 and 2 myocardial infarction
  7. Opinion Paper
  8. Criteria for assigning laboratory measurands to models for analytical performance specifications defined in the 1st EFLM Strategic Conference
  9. Genetics and Molecular Diagnostics
  10. External quality assessment for human papillomavirus 16/18 DNA detection and genotyping in Shanghai, China
  11. General Clinical Chemistry and Laboratory Medicine
  12. Analytical performance of 17 general chemistry analytes across countries and across manufacturers in the INPUtS project of EQA organizers in Italy, the Netherlands, Portugal, United Kingdom and Spain
  13. Commutability of proficiency testing material containing tobramycin: a study within the framework of the Dutch Calibration 2.000 project
  14. Optimization and validation of moving average quality control procedures using bias detection curves and moving average validation charts
  15. Extending laboratory automation to the wards: effect of an innovative pneumatic tube system on diagnostic samples and transport time
  16. Smart management of sample dilution using an artificial neural network to achieve streamlined processes and saving resources: the automated nephelometric testing of serum free light chain as case study
  17. An integrated proteomic and peptidomic assessment of the normal human urinome
  18. An alternative inhibition method for determining cross-reactive allergens
  19. Validation of a new assay for α-synuclein detection in cerebrospinal fluid
  20. Reference Values and Biological Variations
  21. Intra-individual variation of plasma trimethylamine-N-oxide (TMAO), betaine and choline over 1 year
  22. Cancer Diagnostics
  23. Predictive performance of TPA testing for recurrent disease during follow-up after curative intent surgery for colorectal carcinoma
  24. Cardiovascular Diseases
  25. Mid-regional pro-adrenomedullin (MR-proADM) and mid-regional pro-atrial natriuretic peptide (MR-proANP) in severe aortic valve stenosis: association with outcome after transcatheter aortic valve implantation (TAVI)
  26. Association between apolipoprotein E polymorphisms and premature coronary artery disease: a meta-analysis
  27. Urinary orosomucoid: a novel, early biomarker of sepsis with promising diagnostic performance
  28. Letters to the Editor
  29. CT or MRI
  30. Reply to: CT or MRI in the diagnosis of right lower quadrant abdominal pain?
  31. Quantification of daratumumab in the serum protein electrophoresis
  32. Response to: Interference of daratumumab on the serum protein electrophoresis
  33. Glycated albumin: correlation to HbA1c and preliminary reference interval evaluation
  34. Using “big data” to describe the effect of seasonal variation in thyroid-stimulating hormone
  35. IgE multiple myeloma: a new case report
  36. Therapeutic decision-making process in the intensive care unit: role of biological point-of-care testing
  37. How can we evaluate differences between serial measurements on the same sample? A new approach based on within-subject biological variation
Heruntergeladen am 21.9.2025 von https://www.degruyterbrill.com/document/doi/10.1515/cclm-2016-0380/html?lang=de
Button zum nach oben scrollen