Emulsion synthesis of dicalcium phosphate particles for the preparation of calcium phosphate cements with improved compressive strengths and reduced setting times
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Abstract
This study aimed to produce nanosized secondary calcium phosphate powders (CaHPO4, CaHPO4∙2H2O) with a high reactivity by a precipitation reaction in water/oil emulsions. Aqueous mother solutions of CaNO3∙4H2O and NH4H2PO4 were prepared at a concentration of 1.25 mol/l and emulsified with rape seed oil with the addition of 5–10% surfactant (Brij35, Tween20, Tween80) at a water to oil ratio of 1:9. The resulting precipitated powders were predominantly composed of monetite with a medium crystal size of 30–90 nm and showed a high reactivity in cements formed with tetracalcium phosphate as second component. Compared to the use of ground CaHPO4 these cements showed generally shorter setting times of 7–15 min (reference: 24 min) and higher compressive strength of 12–17 MPa (reference: 5.4 MPa). The latter was attributed to both a higher degree of conversion to the setting product hydroxyapatite (>90%) and a preferred growth of HA crystals in (002) direction leading to a better entangling of crystals in the set cement.
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©2013 by Walter de Gruyter Berlin Boston
Artikel in diesem Heft
- Masthead
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- Editorial – BioNanomaterials Drive Innovation in Clinical Research
- Special issue on Nanosafety Part 1
- Editorial
- Editorial by the guest editors
- Reviews
- Human inhalation exposure to iron oxide particles
- Titanium dioxide nanoparticles and the oral uptake-route
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- Letter
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- Regular Research
- Review
- Blood protein and blood cell interactions with gold nanoparticles: the need for in vivo studies
- Highlight
- Emulsion synthesis of dicalcium phosphate particles for the preparation of calcium phosphate cements with improved compressive strengths and reduced setting times
- Letters
- Nanoporous silica coatings on implant surfaces: characterization, stability, biocompatibility and drug release properties
- Ensuring defined porosity and pore size using ammonium hydrogen carbonate as porosification agent for calcium phosphate scaffolds
- On the creation of wall shear stress by helical flow structures in stented coronary vessels
Artikel in diesem Heft
- Masthead
- Masthead
- Editorial
- Editorial – BioNanomaterials Drive Innovation in Clinical Research
- Special issue on Nanosafety Part 1
- Editorial
- Editorial by the guest editors
- Reviews
- Human inhalation exposure to iron oxide particles
- Titanium dioxide nanoparticles and the oral uptake-route
- Highlights
- From nanoobject release of (Bio)nanomaterials to exposure
- Silver nanoparticles induce cytotoxicity, but not cell transformation or genotoxicity on Balb3T3 mouse fibroblasts
- Letter
- A comparative study of metal oxide nanoparticles embryotoxicity using the embryonic stem cell test
- Regular Research
- Review
- Blood protein and blood cell interactions with gold nanoparticles: the need for in vivo studies
- Highlight
- Emulsion synthesis of dicalcium phosphate particles for the preparation of calcium phosphate cements with improved compressive strengths and reduced setting times
- Letters
- Nanoporous silica coatings on implant surfaces: characterization, stability, biocompatibility and drug release properties
- Ensuring defined porosity and pore size using ammonium hydrogen carbonate as porosification agent for calcium phosphate scaffolds
- On the creation of wall shear stress by helical flow structures in stented coronary vessels
