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A seepage outlet boundary condition in hemodynamics modeling

  • Fan He EMAIL logo , Lu Hua und Li-jian Gao
Veröffentlicht/Copyright: 17. Dezember 2016
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Abstract

Background:

In computational fluid dynamics (CFD) models for hemodynamics applications, boundary conditions remain one of the major issues in obtaining accurate fluid flow predictions.

Objective:

As an important part of the arterial circulation, microcirculation plays important roles in many aspects, such as substance exchange, interstitial fluid generation and inverse flow. It is necessary to consider microcirculation in hemodynamics modeling. This is a methodological paper to test and validate a new type of boundary condition never applied to microcirculation before.

Methods:

In order to address this issue, we introduce microcirculation as a seepage outlet boundary condition in computational hemodynamics. Microcirculation is treated as a porous medium in this paper. Numerical comparisons of the seepage and traditional boundary conditions are made.

Results:

The results show that the seepage boundary condition has significant impacts on numerical simulation. Under the seepage boundary condition, the fluctuation range of the pressures progressively rises in the artery zone. The results obtained from the traditional boundary condition show that the pressure fluctuation range gradually falls. In addition, the wall shear stresses under the traditional outlet boundary condition are much higher than those under the seepage outlet boundary condition.

Conclusions:

The proposed boundary condition is more suitable in hemodynamics modeling.

Award Identifier / Grant number: 81401492

Award Identifier / Grant number: KM201510016012

Funding statement: We thank the National Natural Science Foundation of China (81401492), the Science and Technology Project of Beijing Municipal Commission of Education (KM201510016012) for financially supporting this research. The work is also supported by the Foundation of Research and Innovation Team (21147515602) and the Academic Innovation Team of Beijing University of Civil Engineering and Architecture (21221214111). The authors are very grateful to the reviewers for reviewing this manuscript and giving very constructive suggestions.

Acknowledgments

We thank the National Natural Science Foundation of China (81401492), the Science and Technology Project of Beijing Municipal Commission of Education (KM201510016012) for financially supporting this research. The work is also supported by the Foundation of Research and Innovation Team (21147515602) and the Academic Innovation Team of Beijing University of Civil Engineering and Architecture (21221214111). The authors are very grateful to the reviewers for reviewing this manuscript and giving very constructive suggestions.

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Received: 2015-11-21
Accepted: 2016-11-15
Published Online: 2016-12-17
Published in Print: 2017-10-26

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