Assessment of spatial organization in the atria during paroxysmal atrial fibrillation and adrenergic stimulation
-
Valentina D.A. Corino
, Massimo Mantica , Federico Lombardi und Luca T. Mainardi
Abstract
Non-linear parameters were computed to assess the extent of spatial organization in the atria in terms of coupling/synchronization between electrograms recorded in different atrial sites. Recordings of 9 patients suffering from paroxysmal atrial fibrillation were tested during four clinical experimental conditions: sinus rhythm and atrial fibrillation, both before and after isoproterenol infusion, a drug mimicking adrenergic activation. Two non-linear metrics were investigated: an index of non-linear association (NLA) and a synchronization (S) index based on the cross-conditional entropy. Results evidence the presence of reduced coupling after drug infusion in both sinus rhythm and atrial fibrillation. Moreover, passing from the NLA to the S index, the capability of the parameter to capture the subtle changes due to isoproterenol administration increased.
References
1 Alessie MA, Boyden PA, Camm AJ, et al. Pathophysiology and prevention of atrial fibrillation. Circulation2001; 103: 769–777.10.1161/01.CIR.103.5.769Suche in Google Scholar
2 Allessie MA, Lammers WJEP, Bonke FIM. Experimental evaluation of Moe's multiple wavelets hypothesis of atrial fibrillation. In: Zipes DP, Jalife J, editors. Cardiac electrophysiology and arrhythmias. New York: Grune and Stratton Inc. 1985: 265–276.Suche in Google Scholar
3 Hoekstra BPT, Diks CGH, Allessie MA, De Goede J. Nonlinear analysis of epicardial atrial electrograms of electrically induced atrial fibrillation in man. J Cardiovasc Electrophysiol1995; 6: 419–440.10.1111/j.1540-8167.1995.tb00416.xSuche in Google Scholar PubMed
4 Jalife J, Berenfeld O, Skanes A, Mandapati R. Mechanisms of atrial fibrillation: mother rotors or multiple daughter wavelets, or both? J Cardiovasc Electrophysiol1998; 8 (Suppl): 2–12.Suche in Google Scholar
5 Mainardi LT, Corino VDA, Lombardi L, et al. Assessment of the dynamics of atrial signals and local atrial period series during atrial fibrillation: effects of isoproterenol administration. Biomed Eng Online2004; 3: 37.10.1186/1475-925X-3-37Suche in Google Scholar PubMed PubMed Central
6 Moe GK. On the multiple wavelet hypothesis of atrial fibrillation. Arch Int Pharmacodyn Ther1962; 140: 183–188.Suche in Google Scholar
7 Nattel S, Ehrlich JR. Atrial fibrillation. In: Zipes D, Jalife J, editors. Cardiac electrophysiology. From cell to bedside. Philadelphia: WB Saunders 2004: 512–522.10.1016/B0-7216-0323-8/50059-2Suche in Google Scholar
8 Pijn JP, Lopes da Silva F. Propagation of electrical activity: nonlinear associations and time delays between EEG signals. In: Zschocke S, Speckmann EJ, editors. Basic mechanisms of the EEG. Boston: Birkhäuser 1993: 41–59.10.1007/978-1-4612-0341-4_4Suche in Google Scholar
9 Porta A, Baselli G, Lombardi F, Montano N, Malliani A, Cerutti S. Conditional entropy approach for the evaluation of the coupling strength. Biol Cybern1999; 81: 119–129.10.1007/s004220050549Suche in Google Scholar PubMed
10 Sih HJ, Ropella KM, Swiryn S, Gerstenfeld EP, Sahakian AV. Observations from intra-atrial recordings on the termination of electrically induced atrial fibrillation in humans. Pacing Clin Electrophysiol1994; 17: 1231–1242.10.1111/j.1540-8159.1994.tb01490.xSuche in Google Scholar PubMed
©2006 by Walter de Gruyter Berlin New York
Artikel in diesem Heft
- ESGCO 2006 Conference and Meeting of the European Study Group on Cardiovascular Oscillations, Jena, Germany, May 15–17, 2006
- Cardiovascular Oscillations: from methods and models to clinical applications
- Circadian and ultradian rhythms in heart rate variability
- Influence of age, body mass index, and blood pressure on the carotid intima-media thickness in normotensive and hypertensive patients
- Multivariate and multidimensional analysis of cardiovascular oscillations in patients with heart failure
- Multivariate and multiorgan analysis of cardiorespiratory variability signals: the CAP sleep case
- Role of the autonomic nervous system in generating non-linear dynamics in short-term heart period variability
- Non-linear dynamic analysis of the cardiac rhythm during transient myocardial ischemia
- Complex autonomic dysfunction in cardiovascular, intensive care, and schizophrenic patients assessed by autonomic information flow
- Low HRV entropy is strongly associated with myocardial infarction
- Revisiting the potential of time-domain indexes in short-term HRV analysis
- Fractal dimension in health and heart failure
- Spatiotemporal correlation analyses: a new procedure for standardisation of DC magnetocardiograms
- Changes in heart rate variability of athletes during a training camp
- The missing link between cardiovascular rhythm control and myocardial cell modeling
- Model of the sino-atrial and atrio-ventricular nodes of the conduction system of the human heart
- Modelling long-term heart rate variability: an ARFIMA approach
- Clinical correlates of non-linear indices of heart rate variability in chronic heart failure patients
- Recurrence analysis of nocturnal heart rate in sleep apnea patients
- Normalized correlation dimension for heart rate variability analysis
- Complexity of heart rate fluctuations in near-term sheep and human fetuses during sleep
- Differences between heart rate and blood pressure variability in schizophrenia
- Influence of sympathetic vascular regulation on heart-rate scaling structure: spinal cord lesion as a model of progressively impaired autonomic control
- Increase in regularity of fetal heart rate variability with age
- Fetal heart rate variability in growth restricted fetuses
- Frequency modulation between low- and high-frequency components of the heart rate variability spectrum
- Mixed predictability and cross-validation to assess non-linear Granger causality in short cardiovascular variability series
- Assessment of spatial organization in the atria during paroxysmal atrial fibrillation and adrenergic stimulation
- Attenuated autonomic function in multiple organ dysfunction syndrome across three age groups
- Central vasopressin V1a and V1b receptors modulate the cardiovascular response to air-jet stress in conscious rats
- Heart rate asymmetry by Poincaré plots of RR intervals
- Analyses of cardiovascular oscillations for enhanced diagnosis and risk stratification in cardiac diseases and disorders
Artikel in diesem Heft
- ESGCO 2006 Conference and Meeting of the European Study Group on Cardiovascular Oscillations, Jena, Germany, May 15–17, 2006
- Cardiovascular Oscillations: from methods and models to clinical applications
- Circadian and ultradian rhythms in heart rate variability
- Influence of age, body mass index, and blood pressure on the carotid intima-media thickness in normotensive and hypertensive patients
- Multivariate and multidimensional analysis of cardiovascular oscillations in patients with heart failure
- Multivariate and multiorgan analysis of cardiorespiratory variability signals: the CAP sleep case
- Role of the autonomic nervous system in generating non-linear dynamics in short-term heart period variability
- Non-linear dynamic analysis of the cardiac rhythm during transient myocardial ischemia
- Complex autonomic dysfunction in cardiovascular, intensive care, and schizophrenic patients assessed by autonomic information flow
- Low HRV entropy is strongly associated with myocardial infarction
- Revisiting the potential of time-domain indexes in short-term HRV analysis
- Fractal dimension in health and heart failure
- Spatiotemporal correlation analyses: a new procedure for standardisation of DC magnetocardiograms
- Changes in heart rate variability of athletes during a training camp
- The missing link between cardiovascular rhythm control and myocardial cell modeling
- Model of the sino-atrial and atrio-ventricular nodes of the conduction system of the human heart
- Modelling long-term heart rate variability: an ARFIMA approach
- Clinical correlates of non-linear indices of heart rate variability in chronic heart failure patients
- Recurrence analysis of nocturnal heart rate in sleep apnea patients
- Normalized correlation dimension for heart rate variability analysis
- Complexity of heart rate fluctuations in near-term sheep and human fetuses during sleep
- Differences between heart rate and blood pressure variability in schizophrenia
- Influence of sympathetic vascular regulation on heart-rate scaling structure: spinal cord lesion as a model of progressively impaired autonomic control
- Increase in regularity of fetal heart rate variability with age
- Fetal heart rate variability in growth restricted fetuses
- Frequency modulation between low- and high-frequency components of the heart rate variability spectrum
- Mixed predictability and cross-validation to assess non-linear Granger causality in short cardiovascular variability series
- Assessment of spatial organization in the atria during paroxysmal atrial fibrillation and adrenergic stimulation
- Attenuated autonomic function in multiple organ dysfunction syndrome across three age groups
- Central vasopressin V1a and V1b receptors modulate the cardiovascular response to air-jet stress in conscious rats
- Heart rate asymmetry by Poincaré plots of RR intervals
- Analyses of cardiovascular oscillations for enhanced diagnosis and risk stratification in cardiac diseases and disorders