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Differences between heart rate and blood pressure variability in schizophrenia

  • Karl-Jürgen Bär , Michael K. Boettger and Andreas Voss
Published/Copyright: October 25, 2006
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Biomedical Engineering / Biomedizinische Technik
From the journal Volume 51 Issue 4

Abstract

Heart rate and blood pressure variability parameters were assessed to determine the risk of cardiac mortality in schizophrenia. We investigated 21 acute, unmedicated patients with paranoid schizophrenia and 21 matched controls. Cardiovascular parameters obtained included heart rate variability, blood pressure variability, cardiac output and left ventricular work index. All parameters investigated were analyzed using linear and non-linear techniques. These investigations revealed increased left ventricular work index and reduced heart rate variability. Furthermore, blood pressure was significantly higher compared to controls, whereas its variability was unchanged. We conclude that our results reflect autonomic cardiovascular dysregulation in acute schizophrenia.


Corresponding author: Prof. Dr. med. K.-J. Bär, Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, 07743 Jena, Germany Phone: +49-3641-935282 Fax: +49-3641-936217

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Published Online: 2006-10-25
Published in Print: 2006-10-01

©2006 by Walter de Gruyter Berlin New York

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  21. Complexity of heart rate fluctuations in near-term sheep and human fetuses during sleep
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  24. Increase in regularity of fetal heart rate variability with age
  25. Fetal heart rate variability in growth restricted fetuses
  26. Frequency modulation between low- and high-frequency components of the heart rate variability spectrum
  27. Mixed predictability and cross-validation to assess non-linear Granger causality in short cardiovascular variability series
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  29. Attenuated autonomic function in multiple organ dysfunction syndrome across three age groups
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