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Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions

  • Ashish Kumar Pandey
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Micro and Nano Emulsion Technologies
This chapter is in the book Micro and Nano Emulsion Technologies

Abstract

Dermatological treatments often encounter obstacles such as poor drug penetration, instability of active ingredients, and undesirable side effects associated with conventional topical formulations. Micro- and nanoemulsions have emerged as advanced delivery systems capable of overcoming these limitations. Owing to their unique nanoscale architecture, these formulations enhance drug solubilization, stability, and controlled release, while minimizing irritation and systemic exposure. In dermatology, micro/nanoemulsions enable noninvasive, site-specific therapies for a range of skin disorders, including chronic and inflammatory conditions. Innovations such as temperature-, enzyme-, and light/magnetic-responsive emulsions further optimize drug delivery, tailoring treatment to individual patient needs. Ensuring formulation stability and extended shelf life requires careful selection of excipients, packaging materials, and manufacturing techniques. This work presents a comprehensive overview of the structural design, penetration mechanisms, and clinical potential of micro/nanoemulsions, underscoring their transformative role in dermatological therapeutics.

Abstract

Dermatological treatments often encounter obstacles such as poor drug penetration, instability of active ingredients, and undesirable side effects associated with conventional topical formulations. Micro- and nanoemulsions have emerged as advanced delivery systems capable of overcoming these limitations. Owing to their unique nanoscale architecture, these formulations enhance drug solubilization, stability, and controlled release, while minimizing irritation and systemic exposure. In dermatology, micro/nanoemulsions enable noninvasive, site-specific therapies for a range of skin disorders, including chronic and inflammatory conditions. Innovations such as temperature-, enzyme-, and light/magnetic-responsive emulsions further optimize drug delivery, tailoring treatment to individual patient needs. Ensuring formulation stability and extended shelf life requires careful selection of excipients, packaging materials, and manufacturing techniques. This work presents a comprehensive overview of the structural design, penetration mechanisms, and clinical potential of micro/nanoemulsions, underscoring their transformative role in dermatological therapeutics.

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