10 3D-printed stockings for controlled drug delivery
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Ranvijay Kumar
Abstract
Salix alba as a drug has many medicinal benefits like pain relief, anti-inflammatory effects, fever reduction, migraine relief, relief in gastrointestinal discomfort, and menstrual pain relief. This research study aims to develop the Salix alba powderreinforced polycaprolactone (PCL)-polyvinyl alcohol (PVA) composite solution used for the controlled release for additive manufacturing of stockings. Salix alba was reinforced with various compositions of PCL and PVA to manufacture stockings for drug release at a controlled rate. PCL-PVA blended with chloroform to form a gel solution and Salix alba was incorporated by 5 wt.% in each composition. The drug release for each fabricated composite with varied compositions was tested by using UV spectroscopy. From the UV spectroscopy, it was observed that the controlled drug release depended on various parameters such as drug variation of the PVA loading in the PCL matrix and uniformity of the Salix alba particle distribution.
Abstract
Salix alba as a drug has many medicinal benefits like pain relief, anti-inflammatory effects, fever reduction, migraine relief, relief in gastrointestinal discomfort, and menstrual pain relief. This research study aims to develop the Salix alba powderreinforced polycaprolactone (PCL)-polyvinyl alcohol (PVA) composite solution used for the controlled release for additive manufacturing of stockings. Salix alba was reinforced with various compositions of PCL and PVA to manufacture stockings for drug release at a controlled rate. PCL-PVA blended with chloroform to form a gel solution and Salix alba was incorporated by 5 wt.% in each composition. The drug release for each fabricated composite with varied compositions was tested by using UV spectroscopy. From the UV spectroscopy, it was observed that the controlled drug release depended on various parameters such as drug variation of the PVA loading in the PCL matrix and uniformity of the Salix alba particle distribution.
Chapters in this book
- Frontmatter I
- Contents V
- 1 3D-printed smart functional prototypes as sensors and actuators for robotic applications 1
- 2 Biomimetic-based 3D-printed smart implants 17
- 3 3D-printed self-energized energy storage device for biomedical applications 37
- 4 4D printing of smart thermoplastic composites for online health monitoring 57
- 5 Development of 3D metal-printed smart dental implants 77
- 6 3D metal printing of partially absorbable smart orthopedic implant 101
- 7 Metastructure-based metal 3D printing for innovative application 123
- 8 Partially absorbable 3D-printed implant for health monitoring 141
- 9 Smart foot sensors by 3D bioprinting 155
- 10 3D-printed stockings for controlled drug delivery 167
- 11 3D printing-based smart solutions to boost the circular economy 181
- 12 Life cycle analysis for economic and environmental justification of 3D-printed smart functional prototypes 199
- Index 225
Chapters in this book
- Frontmatter I
- Contents V
- 1 3D-printed smart functional prototypes as sensors and actuators for robotic applications 1
- 2 Biomimetic-based 3D-printed smart implants 17
- 3 3D-printed self-energized energy storage device for biomedical applications 37
- 4 4D printing of smart thermoplastic composites for online health monitoring 57
- 5 Development of 3D metal-printed smart dental implants 77
- 6 3D metal printing of partially absorbable smart orthopedic implant 101
- 7 Metastructure-based metal 3D printing for innovative application 123
- 8 Partially absorbable 3D-printed implant for health monitoring 141
- 9 Smart foot sensors by 3D bioprinting 155
- 10 3D-printed stockings for controlled drug delivery 167
- 11 3D printing-based smart solutions to boost the circular economy 181
- 12 Life cycle analysis for economic and environmental justification of 3D-printed smart functional prototypes 199
- Index 225
