2 Biomimetic-based 3D-printed smart implants
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Husain
Abstract
In the past decade, several studies have been reported on polyvinylidene fluoride (PVDF) and its composites for energy storage device applications. Also, some studies have reported the use of PVDF composite as a useful material for the fabrication of implants. But hitherto the detailed procedure for in-house development of PVDF-hydroxyapatite (HAp)-chitosan (CS)-based biomimetic 3D-printed smart implant at the lab level has not been reported. This study highlighted the mechanical properties (tensile, flexural, and compressive) and biocompatibility features based on in vitro testing for the in-house development of PVDF composite. The result of the study suggests that the PVDF composite-based biomimetic 3D-printed smart implants may be used in orthopedic applications for online health monitoring based on the concept of microstrip patch antenna for bone growth. The observation of the biocompatibility test of the PVDF composite shows that the best combination of HAp and CS in the PVDF matrix was noticed in sample 3, that is, the 90% PVDF-8% HAp-2% CS (for the egg-to-adult survival of Drosophila melanogaster). The composition (90% PVDF-8% HAp-2% CS) was used to fabricate the biomimetic-based 3D-printed smart implant. The result suggests that from a multifactor optimization viewpoint, 235 °C nozzle temperature, 40 mm/s printing speed, 60° raster angle (suggested by the regression model), and 90° raster angle (suggested by a general linear model) are the best setting of fused filament fabrication.
Abstract
In the past decade, several studies have been reported on polyvinylidene fluoride (PVDF) and its composites for energy storage device applications. Also, some studies have reported the use of PVDF composite as a useful material for the fabrication of implants. But hitherto the detailed procedure for in-house development of PVDF-hydroxyapatite (HAp)-chitosan (CS)-based biomimetic 3D-printed smart implant at the lab level has not been reported. This study highlighted the mechanical properties (tensile, flexural, and compressive) and biocompatibility features based on in vitro testing for the in-house development of PVDF composite. The result of the study suggests that the PVDF composite-based biomimetic 3D-printed smart implants may be used in orthopedic applications for online health monitoring based on the concept of microstrip patch antenna for bone growth. The observation of the biocompatibility test of the PVDF composite shows that the best combination of HAp and CS in the PVDF matrix was noticed in sample 3, that is, the 90% PVDF-8% HAp-2% CS (for the egg-to-adult survival of Drosophila melanogaster). The composition (90% PVDF-8% HAp-2% CS) was used to fabricate the biomimetic-based 3D-printed smart implant. The result suggests that from a multifactor optimization viewpoint, 235 °C nozzle temperature, 40 mm/s printing speed, 60° raster angle (suggested by the regression model), and 90° raster angle (suggested by a general linear model) are the best setting of fused filament fabrication.
Chapters in this book
- Frontmatter I
- Contents V
- 1 3D-printed smart functional prototypes as sensors and actuators for robotic applications 1
- 2 Biomimetic-based 3D-printed smart implants 17
- 3 3D-printed self-energized energy storage device for biomedical applications 37
- 4 4D printing of smart thermoplastic composites for online health monitoring 57
- 5 Development of 3D metal-printed smart dental implants 77
- 6 3D metal printing of partially absorbable smart orthopedic implant 101
- 7 Metastructure-based metal 3D printing for innovative application 123
- 8 Partially absorbable 3D-printed implant for health monitoring 141
- 9 Smart foot sensors by 3D bioprinting 155
- 10 3D-printed stockings for controlled drug delivery 167
- 11 3D printing-based smart solutions to boost the circular economy 181
- 12 Life cycle analysis for economic and environmental justification of 3D-printed smart functional prototypes 199
- Index 225
Chapters in this book
- Frontmatter I
- Contents V
- 1 3D-printed smart functional prototypes as sensors and actuators for robotic applications 1
- 2 Biomimetic-based 3D-printed smart implants 17
- 3 3D-printed self-energized energy storage device for biomedical applications 37
- 4 4D printing of smart thermoplastic composites for online health monitoring 57
- 5 Development of 3D metal-printed smart dental implants 77
- 6 3D metal printing of partially absorbable smart orthopedic implant 101
- 7 Metastructure-based metal 3D printing for innovative application 123
- 8 Partially absorbable 3D-printed implant for health monitoring 141
- 9 Smart foot sensors by 3D bioprinting 155
- 10 3D-printed stockings for controlled drug delivery 167
- 11 3D printing-based smart solutions to boost the circular economy 181
- 12 Life cycle analysis for economic and environmental justification of 3D-printed smart functional prototypes 199
- Index 225
