In this issue of the Scandinavian Journal of Pain Bendayan and co-workers from Spain, UK, and USA publish an interesting 24 months long follow-up study of 232 patients from Malaga with acute back pain at baseline [1].They followed changes in pain intensity, associated disability and depression, and they could document that pain intensity decreased rapidly during the first three months and typically changed only slowly during the next 21 months. Accompanying depressed mood assessed with the Hospital Anxiety and Depression Scale (HADS) changed slowly during the entire 24 months period. Disability assessed with the Roland-Morris Questionnaire also decreased only slightly during the entire 24 months period of follow-up. Women and elderly patients reported higher pain intensities and pain-related disabilities during the first three months than men and younger patients.
1 Chronification of acute pain – a continuous ongoing process from the start of acute pain
The authors indicate that the transition of acute back pain to a chronic pain condition, that the authors call chronification of acute pain, is a continuous process from the very beginning of an acute attack of back pain. They argue well that the very arbitrary definition of acute pain lasting more than three months – being a chronic pain condition, indeed is an arbitrary definition. This is also the case with acute pain after surgery: We have become accustomed to naming postoperative pain a chronic postoperative pain condition when the patients have bothersome pain lasting more than 3 months after surgery.
2 Risk factors for chronification of acute postoperative pain
Focus has increased on this phenomenon: In about 10% of all patients having surgery there will be longer lasting pain, but acute postoperative pain in most patients will resolve after another few months. However, for reasons that we only partly understand, in about 1 in 100 surgical patients, the acute pain transforms to a chronic state. Our understanding of the risk factors that underlie the development of chronic pain is limited. However, we know that patients who had chronic pain in another part of the body is more likely to develop chronic pain after surgery. Also patients who are extremely stressed from severe social problem during the months before surgery (marriage-problems, death of a family member, etc.), they have a higher risk of having chronic pain after an operation. Women are at higher risk than male surgical patients. Most important is that acute pain poorly managed during the first days after surgery have high risk of ending as a chronic postoperative pain condition. It is double tragic when chronic pain develops when the indication for a surgical intervention is weak, e.g. breast augmentation surgery, and other cosmetic indications for surgery.
3 Optimal acute pain management should be obligatory
Many anaesthesiologists are making significant efforts to improve routine pain management after surgery [2,3]. In Helsinki Eija Kalso and her co-workers are doing this by extending the responsibilities of their acute postoperative pain service to intensify and prolong specialized management of abnormally severe pain after surgery, even referring the patient to the chronic pain clinic of the hospital [4,5]. This is highly recommended to all surgical hospitals: It is a great sin of negligence to send a postoperative patient with severe pain home without a detailed programme for how and by whom the management of severe postoperative pain is continued at home [4,5].
DOI of refers to article: http://dx.doi.org/10.1016/j.sjpain.2017.02.009.
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Conflict of interest: None declared.
References
[1] Bendayan R, Ramírez-Maestrec C, Ferrerd E, López A, Esteve R. From acute to chronic back pain: using linear mixed models to explore changes in pain intensity, disability, and depression. Scand J Pain 2017;16:45–51.Suche in Google Scholar
[2] Pergolizzi J, Ahlbeck K, Aldington D, Alon E, Coluzzi F, Dahan A, Huygen F, Kocot-Kępska M, Mangas AC, Mavrocordatos P, Morlion B, Müller-Schwefe G, Nicolaou A, Hernández CP, Sichère P, Schäfer M, Varrassi G. The development of chronic pain: physiological change necessitates a multidisciplinary approach to treatment. Curr Med Res Opin 2013;29:1127–35.Suche in Google Scholar
[3] Meissner W, Coluzzi F, Fletcher D, Huygen F, MorlionB, Neugebauer E, Montes A, Pérez J. Improving the management of post-operative acute pain: priorities for change. Curr Med Res Opin 2015;31:2131–43.Suche in Google Scholar
[4] Tiippana E, Hamunen K, Heiskanen T, Nieminen T, Kalso E, Kontinen VK. New approach for treatment of prolonged postoperative pain: APS Out-Patient Clinic. Scand J Pain 2016;12:19–24.Suche in Google Scholar
[5] Staehelin Jensen T, Stubhaug A, Breivik H. Important development: Extended Acute Pain Service for patients at high risk of chronic pain after surgery. Scand J Pain 2016;12:58–9.Suche in Google Scholar
© 2017 Scandinavian Association for the Study of Pain
Artikel in diesem Heft
- Scandinavian Journal of Pain
- Editorial comment
- Glucocorticoids – Efficient analgesics against postherpetic neuralgia?
- Original experimental
- Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model
- Editorial comment
- Important new insight in pain and pain treatment induced changes in functional connectivity between the Pain Matrix and the Salience, Central Executive, and Sensorimotor networks
- Original experimental
- Salience, central executive, and sensorimotor network functional connectivity alterations in failed back surgery syndrome
- Editorial comment
- Education and support strategies improve assessment and management of pain by nurses
- Clinical pain research
- Using education and support strategies to improve the way nurses assess regular and transient pain – A quality improvement study of three hospitals
- Editorial comment
- The interference of pain with task performance: Increasing ecological validity in research
- Original experimental
- The disruptive effects of pain on multitasking in a virtual errands task
- Editorial comment
- Analyzing transition from acute back pain to chronic pain with linear mixed models reveals a continuous chronification of acute back pain
- Observational study
- From acute to chronic back pain: Using linear mixed models to explore changes in pain intensity, disability, and depression
- Editorial comment
- NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
- Clinical pain research
- Efficacy and safety of diclofenac in osteoarthritis: Results of a network meta-analysis of unpublished legacy studies
- Editorial comment
- Editorial comment on Nina Kreddig’s and Monika Hasenbring’s study on pain anxiety and fear of (re) injury in patients with chronic back pain: Sex as a moderator
- Clinical pain research
- Pain anxiety and fear of (re) injury in patients with chronic back pain: Sex as a moderator
- Editorial comment
- Intraoral QST – Mission impossible or not?
- Clinical pain research
- Multifactorial assessment of measurement errors affecting intraoral quantitative sensory testing reliability
- Editorial comment
- Objective measurement of subjective pain-experience: Real nociceptive stimuli versus pain expectation
- Clinical pain research
- Cerebral oxygenation for pain monitoring in adults is ineffective: A sequence-randomized, sham controlled study in volunteers
- Editorial comment
- Association between adolescent and parental use of analgesics
- Observational study
- The association between adolescent and parental use of non-prescription analgesics for headache and other somatic pain – A cross-sectional study
- Editorial comment
- Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist
- Clinical pain research
- Spinal analgesia for severe cancer pain: A retrospective analysis of 60 patients
- Editorial comment
- Specific symptoms and signs of unstable back segments and curative surgery?
- Clinical pain research
- Symptoms and signs possibly indicating segmental, discogenic pain. A fusion study with 18 years of follow-up
- Editorial comment
- Local anaesthesia methods for analgesia after total hip replacement: Problems of anatomy, methodology and interpretation?
- Clinical pain research
- Local infiltration analgesia or femoral nerve block for postoperative pain management in patients undergoing total hip arthroplasty. A randomized, double-blind study
- Editorial
- Scientific presentations at the 2017 annual meeting of the Scandinavian Association for the Study of Pain (SASP)
- Abstracts
- Correlation between quality of pain and depression: A post-operative assessment of pain after caesarian section among women in Ghana
- Abstracts
- Dynamic and static mechanical pain sensitivity is associated in women with migraine
- Abstracts
- The number of active trigger points is associated with sensory and emotional aspects of health-related quality of life in tension type headache
- Abstracts
- Chronic neuropathic pain following oxaliplatin and docetaxel: A 5-year follow-up questionnaire study
- Abstracts
- Expression of α1 adrenergic receptor subtypes by afferent fibers that innervate rat masseter muscle
- Abstracts
- Buprenorphine alleviation of pain does not compromise the rat monoarthritic pain model
- Abstracts
- Association between pain, disability, widespread pressure pain hypersensitivity and trigger points in subjects with neck pain
- Abstracts
- Association between widespread pressure pain hypersensitivity, health history, and trigger points in subjects with neck pain
- Abstracts
- Neuromas in patients with peripheral nerve injury and amputation - An ongoing study
- Abstracts
- The link between chronic musculoskeletal pain and sperm quality in overweight orthopedic patients
- Abstracts
- Several days of muscle hyperalgesia facilitates cortical somatosensory excitability
- Abstracts
- Social stress, epigenetic changes and pain
- Abstracts
- Characterization of released exosomes from satellite glial cells under normal and inflammatory conditions
- Abstracts
- Cell-based platform for studying trigeminal satellite glial cells under normal and inflammatory conditions
- Abstracts
- Tramadol in postoperative pain – 1 mg/ml IV gave no pain reduction but more side effects in third molar surgery
- Abstracts
- Tempo-spatial discrimination to non-noxious stimuli is better than for noxious stimuli
- Abstracts
- The encoding of the thermal grill illusion in the human spinal cord
- Abstracts
- Effect of cocoa on endorphin levels and craniofacial muscle sensitivity in healthy individuals
- Abstracts
- The impact of naloxegol treatment on gastrointestinal transit and colonic volume
- Abstracts
- Preoperative downregulation of long-noncoding RNA Meg3 in serum of patients with chronic postoperative pain after total knee replacement
- Abstracts
- Painful diabetic polyneuropathy and quality of life in Danish type 2 diabetic patients
- Abstracts
- “What about me?”: A qualitative explorative study on perspectives of spouses living with complex chronic pain patients
- Abstracts
- Increased postural stiffness in patients with knee osteoarthritis who are highly sensitized
- Abstracts
- Efficacy of dry needling on latent myofascial trigger points in male subjects with neck/shoulders musculoskeletal pain. A case series
- Abstracts
- Identification of pre-operative of risk factors associated with persistent post-operative pain by self-reporting tools in lower limb amputee patients – A feasibility study
- Abstracts
- Renal function estimations and dose recommendations for Gabapentin, Ibuprofen and Morphine in acute hip fracture patients
- Abstracts
- Evaluating the ability of non-rectangular electrical pulse forms to preferentially activate nociceptive fibers by comparing perception thresholds
- Abstracts
- Detection of systemic inflammation in severely impaired chronic pain patients, and effects of a CBT-ACT-based multi-modal pain rehabilitation program
- Abstracts
- Fixed or adapted conditioning intensity for repeated conditioned pain modulation
- Abstracts
- Combined treatment (Norspan, Gabapentin and Oxynorm) was found superior in pain management after total knee arthroplasty
- Abstracts
- Effects of conditioned pain modulation on the withdrawal pattern to nociceptive stimulation in humans – Preliminary results
- Abstracts
- Application of miR-223 onto the dorsal nerve roots in rats induces hypoexcitability in the pain pathways
- Abstracts
- Acute muscle pain alters corticomotor output of the affected muscle stronger than a synergistic, ipsilateral muscle
- Abstracts
- The subjective sensation induced by various thermal pulse stimulation in healthy volunteers
- Abstracts
- Assessing Offset Analgesia through electrical stimulations in healthy volunteers
- Abstracts
- Metastatic lung cancer in patient with non-malignant neck pain: A case report
- Abstracts
- The size of pain referral patterns from a tonic painful mechanical stimulus is increased in women
- Abstracts
- Oxycodone and macrogol 3350 treatment reduces anal sphincter relaxation compared to combined oxycodone and naloxone tablets
- Abstracts
- The effect of UVB-induced skin inflammation on histaminergic and non-histaminergic evoked itch and pain
- Abstracts
- Topical allyl-isothiocyanate (mustard oil) as a TRPA1-dependent human surrogate model of pain, hyperalgesia, and neurogenic inflammation – A dose response study
- Abstracts
- Dissatisfaction and persistent post-operative pain following total knee replacement – A 5 year follow-up of all patients from a whole region
- Abstracts
- Paradoxical differences in pain ratings of the same stimulus intensity
- Abstracts
- Pain assessment and post-operative pain management in orthopedic patients
- Abstracts
- Combined electric and pressure cuff pain stimuli for assessing conditioning pain modulation (CPM)
- Abstracts
- The effect of facilitated temporal summation of pain, widespread pressure hyperalgesia and pain intensity in patients with knee osteoarthritis on the responds to Non-Steroidal Anti-Inflammatory Drugs – A preliminary analysis
- Abstracts
- How to obtain the biopsychosocial record in multidisciplinary pain clinic? An action research study
- Abstracts
- Experimental neck muscle pain increase pressure pain threshold over cervical facet joints
- Abstracts
- Are we using Placebo effects in specialized Palliative Care?
- Abstracts
- Prevalence and pattern of helmet-induced headache among Danish military personnel
- Abstracts
- Aquaporin 4 expression on trigeminal satellite glial cells under normal and inflammatory conditions
- Abstracts
- Preoperative synovitis in knee osteoarthritis is predictive for pain 1 year after total knee arthroplasty
- Abstracts
- Biomarkers alterations in trapezius muscle after an acute tissue trauma: A human microdialysis study
- Abstracts
- PainData: A clinical pain registry in Denmark
- Abstracts
- A novel method for investigating the importance of visual feedback on somatosensation and bodily-self perception
- Abstracts
- Drugs that can cause respiratory depression with concomitant use of opioids
- Abstracts
- The potential use of a serious game to help patients learn about post-operative pain management – An evaluation study
- Abstracts
- Modelling activity-dependent changes of velocity in C-fibers
- Abstracts
- Choice of rat strain in pre-clinical pain-research – Does it make a difference for translation from animal model to human condition?
- Abstracts
- Omics as a potential tool to identify biomarkers and to clarify the mechanism of chronic pain development
- Abstracts
- Evaluation of the benefits from the introduction meeting for patients with chronic non-malignant pain and their relatives in interdisciplinary pain center
- Observational study
- The changing face of acute pain services
- Observational study
- Chronic pain in multiple sclerosis: A10-year longitudinal study
- Clinical pain research
- Functional disability and depression symptoms in a paediatric persistent pain sample
- Observational study
- Pain provocation following sagittal plane repeated movements in people with chronic low back pain: Associations with pain sensitivity and psychological profiles
- Observational study
- A longitudinal exploration of pain tolerance and participation in contact sports
- Original experimental
- Taking a break in response to pain. An experimental investigation of the effects of interruptions by pain on subsequent activity resumption
- Clinical pain research
- Sex moderates the effects of positive and negative affect on clinical pain in patients with knee osteoarthritis
- Original experimental
- The effects of a brief educational intervention on medical students’ knowledge, attitudes and beliefs towards low back pain
- Observational study
- The association between pain characteristics, pain catastrophizing and health care use – Baseline results from the SWEPAIN cohort
- Topical review
- Couples coping with chronic pain: How do intercouple interactions relate to pain coping?
- Narrative review
- The wit and wisdom of Wilbert (Bill) Fordyce (1923 - 2009)
- Letter to the Editor
- Unjustified extrapolation
- Letter to the Editor
- Response to: “Letter to the Editor entitled: Unjustified extrapolation” [by authors: Supp G., Rosedale R., Werneke M.]
Artikel in diesem Heft
- Scandinavian Journal of Pain
- Editorial comment
- Glucocorticoids – Efficient analgesics against postherpetic neuralgia?
- Original experimental
- Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model
- Editorial comment
- Important new insight in pain and pain treatment induced changes in functional connectivity between the Pain Matrix and the Salience, Central Executive, and Sensorimotor networks
- Original experimental
- Salience, central executive, and sensorimotor network functional connectivity alterations in failed back surgery syndrome
- Editorial comment
- Education and support strategies improve assessment and management of pain by nurses
- Clinical pain research
- Using education and support strategies to improve the way nurses assess regular and transient pain – A quality improvement study of three hospitals
- Editorial comment
- The interference of pain with task performance: Increasing ecological validity in research
- Original experimental
- The disruptive effects of pain on multitasking in a virtual errands task
- Editorial comment
- Analyzing transition from acute back pain to chronic pain with linear mixed models reveals a continuous chronification of acute back pain
- Observational study
- From acute to chronic back pain: Using linear mixed models to explore changes in pain intensity, disability, and depression
- Editorial comment
- NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
- Clinical pain research
- Efficacy and safety of diclofenac in osteoarthritis: Results of a network meta-analysis of unpublished legacy studies
- Editorial comment
- Editorial comment on Nina Kreddig’s and Monika Hasenbring’s study on pain anxiety and fear of (re) injury in patients with chronic back pain: Sex as a moderator
- Clinical pain research
- Pain anxiety and fear of (re) injury in patients with chronic back pain: Sex as a moderator
- Editorial comment
- Intraoral QST – Mission impossible or not?
- Clinical pain research
- Multifactorial assessment of measurement errors affecting intraoral quantitative sensory testing reliability
- Editorial comment
- Objective measurement of subjective pain-experience: Real nociceptive stimuli versus pain expectation
- Clinical pain research
- Cerebral oxygenation for pain monitoring in adults is ineffective: A sequence-randomized, sham controlled study in volunteers
- Editorial comment
- Association between adolescent and parental use of analgesics
- Observational study
- The association between adolescent and parental use of non-prescription analgesics for headache and other somatic pain – A cross-sectional study
- Editorial comment
- Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist
- Clinical pain research
- Spinal analgesia for severe cancer pain: A retrospective analysis of 60 patients
- Editorial comment
- Specific symptoms and signs of unstable back segments and curative surgery?
- Clinical pain research
- Symptoms and signs possibly indicating segmental, discogenic pain. A fusion study with 18 years of follow-up
- Editorial comment
- Local anaesthesia methods for analgesia after total hip replacement: Problems of anatomy, methodology and interpretation?
- Clinical pain research
- Local infiltration analgesia or femoral nerve block for postoperative pain management in patients undergoing total hip arthroplasty. A randomized, double-blind study
- Editorial
- Scientific presentations at the 2017 annual meeting of the Scandinavian Association for the Study of Pain (SASP)
- Abstracts
- Correlation between quality of pain and depression: A post-operative assessment of pain after caesarian section among women in Ghana
- Abstracts
- Dynamic and static mechanical pain sensitivity is associated in women with migraine
- Abstracts
- The number of active trigger points is associated with sensory and emotional aspects of health-related quality of life in tension type headache
- Abstracts
- Chronic neuropathic pain following oxaliplatin and docetaxel: A 5-year follow-up questionnaire study
- Abstracts
- Expression of α1 adrenergic receptor subtypes by afferent fibers that innervate rat masseter muscle
- Abstracts
- Buprenorphine alleviation of pain does not compromise the rat monoarthritic pain model
- Abstracts
- Association between pain, disability, widespread pressure pain hypersensitivity and trigger points in subjects with neck pain
- Abstracts
- Association between widespread pressure pain hypersensitivity, health history, and trigger points in subjects with neck pain
- Abstracts
- Neuromas in patients with peripheral nerve injury and amputation - An ongoing study
- Abstracts
- The link between chronic musculoskeletal pain and sperm quality in overweight orthopedic patients
- Abstracts
- Several days of muscle hyperalgesia facilitates cortical somatosensory excitability
- Abstracts
- Social stress, epigenetic changes and pain
- Abstracts
- Characterization of released exosomes from satellite glial cells under normal and inflammatory conditions
- Abstracts
- Cell-based platform for studying trigeminal satellite glial cells under normal and inflammatory conditions
- Abstracts
- Tramadol in postoperative pain – 1 mg/ml IV gave no pain reduction but more side effects in third molar surgery
- Abstracts
- Tempo-spatial discrimination to non-noxious stimuli is better than for noxious stimuli
- Abstracts
- The encoding of the thermal grill illusion in the human spinal cord
- Abstracts
- Effect of cocoa on endorphin levels and craniofacial muscle sensitivity in healthy individuals
- Abstracts
- The impact of naloxegol treatment on gastrointestinal transit and colonic volume
- Abstracts
- Preoperative downregulation of long-noncoding RNA Meg3 in serum of patients with chronic postoperative pain after total knee replacement
- Abstracts
- Painful diabetic polyneuropathy and quality of life in Danish type 2 diabetic patients
- Abstracts
- “What about me?”: A qualitative explorative study on perspectives of spouses living with complex chronic pain patients
- Abstracts
- Increased postural stiffness in patients with knee osteoarthritis who are highly sensitized
- Abstracts
- Efficacy of dry needling on latent myofascial trigger points in male subjects with neck/shoulders musculoskeletal pain. A case series
- Abstracts
- Identification of pre-operative of risk factors associated with persistent post-operative pain by self-reporting tools in lower limb amputee patients – A feasibility study
- Abstracts
- Renal function estimations and dose recommendations for Gabapentin, Ibuprofen and Morphine in acute hip fracture patients
- Abstracts
- Evaluating the ability of non-rectangular electrical pulse forms to preferentially activate nociceptive fibers by comparing perception thresholds
- Abstracts
- Detection of systemic inflammation in severely impaired chronic pain patients, and effects of a CBT-ACT-based multi-modal pain rehabilitation program
- Abstracts
- Fixed or adapted conditioning intensity for repeated conditioned pain modulation
- Abstracts
- Combined treatment (Norspan, Gabapentin and Oxynorm) was found superior in pain management after total knee arthroplasty
- Abstracts
- Effects of conditioned pain modulation on the withdrawal pattern to nociceptive stimulation in humans – Preliminary results
- Abstracts
- Application of miR-223 onto the dorsal nerve roots in rats induces hypoexcitability in the pain pathways
- Abstracts
- Acute muscle pain alters corticomotor output of the affected muscle stronger than a synergistic, ipsilateral muscle
- Abstracts
- The subjective sensation induced by various thermal pulse stimulation in healthy volunteers
- Abstracts
- Assessing Offset Analgesia through electrical stimulations in healthy volunteers
- Abstracts
- Metastatic lung cancer in patient with non-malignant neck pain: A case report
- Abstracts
- The size of pain referral patterns from a tonic painful mechanical stimulus is increased in women
- Abstracts
- Oxycodone and macrogol 3350 treatment reduces anal sphincter relaxation compared to combined oxycodone and naloxone tablets
- Abstracts
- The effect of UVB-induced skin inflammation on histaminergic and non-histaminergic evoked itch and pain
- Abstracts
- Topical allyl-isothiocyanate (mustard oil) as a TRPA1-dependent human surrogate model of pain, hyperalgesia, and neurogenic inflammation – A dose response study
- Abstracts
- Dissatisfaction and persistent post-operative pain following total knee replacement – A 5 year follow-up of all patients from a whole region
- Abstracts
- Paradoxical differences in pain ratings of the same stimulus intensity
- Abstracts
- Pain assessment and post-operative pain management in orthopedic patients
- Abstracts
- Combined electric and pressure cuff pain stimuli for assessing conditioning pain modulation (CPM)
- Abstracts
- The effect of facilitated temporal summation of pain, widespread pressure hyperalgesia and pain intensity in patients with knee osteoarthritis on the responds to Non-Steroidal Anti-Inflammatory Drugs – A preliminary analysis
- Abstracts
- How to obtain the biopsychosocial record in multidisciplinary pain clinic? An action research study
- Abstracts
- Experimental neck muscle pain increase pressure pain threshold over cervical facet joints
- Abstracts
- Are we using Placebo effects in specialized Palliative Care?
- Abstracts
- Prevalence and pattern of helmet-induced headache among Danish military personnel
- Abstracts
- Aquaporin 4 expression on trigeminal satellite glial cells under normal and inflammatory conditions
- Abstracts
- Preoperative synovitis in knee osteoarthritis is predictive for pain 1 year after total knee arthroplasty
- Abstracts
- Biomarkers alterations in trapezius muscle after an acute tissue trauma: A human microdialysis study
- Abstracts
- PainData: A clinical pain registry in Denmark
- Abstracts
- A novel method for investigating the importance of visual feedback on somatosensation and bodily-self perception
- Abstracts
- Drugs that can cause respiratory depression with concomitant use of opioids
- Abstracts
- The potential use of a serious game to help patients learn about post-operative pain management – An evaluation study
- Abstracts
- Modelling activity-dependent changes of velocity in C-fibers
- Abstracts
- Choice of rat strain in pre-clinical pain-research – Does it make a difference for translation from animal model to human condition?
- Abstracts
- Omics as a potential tool to identify biomarkers and to clarify the mechanism of chronic pain development
- Abstracts
- Evaluation of the benefits from the introduction meeting for patients with chronic non-malignant pain and their relatives in interdisciplinary pain center
- Observational study
- The changing face of acute pain services
- Observational study
- Chronic pain in multiple sclerosis: A10-year longitudinal study
- Clinical pain research
- Functional disability and depression symptoms in a paediatric persistent pain sample
- Observational study
- Pain provocation following sagittal plane repeated movements in people with chronic low back pain: Associations with pain sensitivity and psychological profiles
- Observational study
- A longitudinal exploration of pain tolerance and participation in contact sports
- Original experimental
- Taking a break in response to pain. An experimental investigation of the effects of interruptions by pain on subsequent activity resumption
- Clinical pain research
- Sex moderates the effects of positive and negative affect on clinical pain in patients with knee osteoarthritis
- Original experimental
- The effects of a brief educational intervention on medical students’ knowledge, attitudes and beliefs towards low back pain
- Observational study
- The association between pain characteristics, pain catastrophizing and health care use – Baseline results from the SWEPAIN cohort
- Topical review
- Couples coping with chronic pain: How do intercouple interactions relate to pain coping?
- Narrative review
- The wit and wisdom of Wilbert (Bill) Fordyce (1923 - 2009)
- Letter to the Editor
- Unjustified extrapolation
- Letter to the Editor
- Response to: “Letter to the Editor entitled: Unjustified extrapolation” [by authors: Supp G., Rosedale R., Werneke M.]