Home Crystal structure of 4-(4-((3-bromophenyl)amino)-6-(tert-butyl)-3-(2-hydroxypropan-2-yl)cinnolin-8-yl)-2-methylbut-3-yn-2-ol, C26H30BrN3O2
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Crystal structure of 4-(4-((3-bromophenyl)amino)-6-(tert-butyl)-3-(2-hydroxypropan-2-yl)cinnolin-8-yl)-2-methylbut-3-yn-2-ol, C26H30BrN3O2

  • Yue-Hua Yuan , Qiang-Feng Yin , Mao-Zhong Tian EMAIL logo and Feng Feng
Published/Copyright: September 17, 2016
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Zeitschrift für Kristallographie - New Crystal Structures
From the journal Zeitschrift für Kristallographie - New Crystal Structures Volume 231 Issue 4

Abstract

C26H30BrN3O2, triclinic, P1̅ (no. 2), a = 12.257(3) Å, b = 12.451(3) Å, c = 17.325(3) Å, α = 92.05(3)°, β = 107.04(3)°, γ = 93.96(3)°, V = 2517.5(10) Å3, Z = 4, Rgt(F) = 0.0722, wRref(F2) = 0.1929, T = 173(2) K.

CCDC no.:: 1402222

Table 1

Data collection and handling.

Crystal:Orange plate

Size 0.16 × 0.14 × 0.04 mm
Wavelength:Mo Kα radiation (0.71073 Å)
μ:16.6 cm−1
Diffractometer, scan mode:Saturn 724, ωat fixed χ = 45°
2θmax, completeness:51°, >99%
N(hkl)measured, N(hkl)unique, Rint:28966, 9336, 0.042
Criterion for Iobs, N(hkl)gt:Iobs > 2 σ(Iobs), 7908
N(param)refined:592
Programs:SHELX [5], CrystalClear [6]
Table 2

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2).

AtomxyzUiso*/Ueq
Br10.69755(5)0.09543(4)0.61078(3)0.05245(19)
Br1A0.83683(5)0.57930(5)0.54202(3)0.0677(2)
O10.1623(2)0.0960(3)0.29907(18)0.0422(8)
H10.19920.04620.32280.063*
O2A0.6703(2)0.2274(2)−0.06517(15)0.0268(6)
H2A0.62070.2607−0.05180.040*
N10.3822(3)0.1812(3)0.3446(2)0.0347(8)
H1B0.31190.19770.33960.042*
N1A0.5305(3)0.6930(3)0.28265(19)0.0279(7)
H1A0.46740.72670.26840.033*
N20.3052(3)−0.0094(3)0.17515(18)0.0240(7)
N2A0.4546(3)0.4683(3)0.13016(19)0.0275(7)
N30.4085(3)−0.0388(3)0.17496(18)0.0237(7)
N3A0.5547(3)0.4443(3)0.12276(19)0.0266(7)
C10.4702(3)0.2205(4)0.4159(2)0.0327(9)
C1A0.6112(3)0.7262(3)0.3583(2)0.0264(8)
C20.5318(4)0.1506(4)0.4679(2)0.0350(9)
H20.51850.07500.45550.042*
C2A0.6723(3)0.6504(3)0.4058(2)0.0321(9)
H2AA0.65890.57600.38880.039*
C30.6141(4)0.1913(4)0.5391(3)0.0369(10)
C3A0.7533(4)0.6849(4)0.4785(3)0.0377(10)
C40.6343(4)0.3012(4)0.5569(3)0.0422(11)
H40.69020.32880.60540.051*
C4A0.7732(4)0.7920(4)0.5052(3)0.0419(11)
H4A0.82980.81470.55470.050*
C50.5742(4)0.3690(4)0.5052(3)0.0418(11)
H50.59080.44460.51690.050*
C5A0.7088(4)0.8650(4)0.4583(3)0.0431(12)
H5A0.71990.93890.47660.052*
C60.4880(4)0.3316(4)0.4349(3)0.0425(11)
H60.44270.38030.40100.051*
C6A0.6280(4)0.8336(4)0.3847(3)0.0344(9)
H6A0.58480.88550.35300.041*
C70.3996(3)0.1226(3)0.2865(2)0.0282(8)
C7A0.5421(3)0.6131(3)0.2296(2)0.0228(8)
C80.2986(3)0.0680(3)0.2255(2)0.0238(8)
C8A0.4460(3)0.5480(3)0.1821(2)0.0242(8)
C90.5093(3)0.0182(3)0.2173(2)0.0233(8)
C9A0.6508(3)0.5047(3)0.1661(2)0.0240(8)
C100.5091(3)0.1025(3)0.2728(2)0.0226(7)
C10A0.6492(3)0.5941(3)0.2181(2)0.0241(8)
C110.6118(3)0.1654(3)0.3107(2)0.0262(8)
H110.61050.22570.34550.031*
C11A0.7521(3)0.6609(3)0.2534(2)0.0253(8)
H11A0.74940.72540.28350.030*
C120.7149(3)0.1425(3)0.2991(2)0.0274(8)
C12A0.8547(3)0.6349(3)0.2453(2)0.0259(8)
C130.7132(3)0.0546(3)0.2454(2)0.0280(8)
H130.78360.03600.23810.034*
C13A0.8566(3)0.5393(3)0.1989(2)0.0261(8)
H13A0.92830.51770.19620.031*
C140.6140(3)−0.0059(3)0.2028(2)0.0238(8)
C14A0.7590(3)0.4771(3)0.1581(2)0.0257(8)
C150.1784(3)0.0993(3)0.2204(2)0.0295(9)
C15A0.3254(3)0.5563(3)0.1897(2)0.0268(8)
C160.1637(4)0.2129(4)0.1914(3)0.0447(11)
H16D0.08580.23140.18690.067*
H16E0.17690.21610.13840.067*
H16F0.21900.26410.23010.067*
C16A0.3189(4)0.5050(4)0.2671(3)0.0366(10)
H16A0.37590.54300.31370.055*
H16B0.33450.42900.26440.055*
H16C0.24220.51000.27280.055*
C170.0854(3)0.0207(4)0.1662(3)0.0385(10)
H17D0.0957−0.05210.18540.058*
H17E0.08980.02170.11070.058*
H17F0.01030.04180.16760.058*
C17A0.2330(3)0.5038(3)0.1164(3)0.0326(9)
H17A0.15730.51700.12140.049*
H17B0.24010.42590.11360.049*
H17C0.24200.53460.06720.049*
C180.6116(3)−0.0879(3)0.1419(2)0.0249(8)
C18A0.7635(3)0.3847(3)0.1068(2)0.0278(8)
C190.6044(3)−0.1525(3)0.0882(2)0.0261(8)
C19A0.7702(3)0.3106(3)0.0636(2)0.0275(8)
C200.5946(3)−0.2313(3)0.0200(2)0.0237(8)
C20A0.7683(3)0.2194(3)0.0056(2)0.0260(8)
C210.5671(4)−0.1764(4)−0.0597(2)0.0372(10)
H21D0.5573−0.2305−0.10420.056*
H21E0.6300−0.1228−0.05870.056*
H21F0.4962−0.1406−0.06760.056*
C21A0.8747(3)0.2284(4)−0.0232(3)0.0363(10)
H21A0.86790.1716−0.06540.054*
H21B0.94260.22020.02250.054*
H21C0.88190.2992−0.04500.054*
C220.7053(3)−0.2878(3)0.0334(2)0.0313(9)
H22D0.7236−0.32050.08580.047*
H22E0.7681−0.23490.03270.047*
H22F0.6951−0.3440−0.00980.047*
C22A0.7555(4)0.1117(3)0.0419(3)0.0385(10)
H22A0.68250.10480.05440.058*
H22B0.81870.10780.09150.058*
H22C0.75710.05310.00300.058*
C230.8273(3)0.2081(4)0.3455(3)0.0353(10)
C23A0.9663(3)0.7045(3)0.2855(2)0.0314(9)
C240.8062(5)0.3222(5)0.3711(4)0.072(2)
H24D0.75970.35650.32390.107*
H24E0.87970.36500.39360.107*
H24F0.76560.31810.41210.107*
C24A0.9444(4)0.8161(4)0.3155(4)0.0653(18)
H24A0.89350.85120.27060.098*
H24B1.01720.86040.33620.098*
H24C0.90830.80810.35870.098*
C250.9073(4)0.2212(4)0.2929(3)0.0446(12)
H25D0.93220.15080.28180.067*
H25E0.97420.27020.32140.067*
H25F0.86670.25120.24190.067*
C25A1.0364(4)0.7203(4)0.2263(3)0.0501(13)
H25A1.05880.65040.21120.075*
H25B1.10520.76850.25200.075*
H25C0.99020.75210.17780.075*
C260.8840(5)0.1492(6)0.4194(3)0.075(2)
H26D0.83180.13970.45250.113*
H26E0.95450.19110.45110.113*
H26F0.90240.07830.40260.113*
C26A1.0349(5)0.6445(5)0.3571(3)0.0642(16)
H26A0.98860.62990.39360.096*
H26B1.10500.68900.38630.096*
H26C1.05510.57630.33720.096*
O1A0.3055(2)0.6683(2)0.19970(16)0.0287(6)
H1AA0.30590.69940.15750.043*
O20.5014(2)−0.3088(2)0.02006(16)0.0271(6)
H2B0.4803−0.3513−0.02130.041*

One of two molecules of the asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details of the measurement method and a list of the atoms including atomic coordinates and displacement parameters.

Source of material

All solvents and reagents for synthesis were purchased from commercial sources and used without further purification. 2,6-Bis(3-methyl-3-hydroxyl-1-butynyl)-4-tert-butylaniline was prepared according to reference [1]. To a stirred MeOH solution (5 mL) of 2,6-bis(3-methyl-3-hydroxyl-1-butynyl)-4-tert-butylaniline (0.626 g, 2 mmol) was added slowly conc. HCl (2.5 mL). The reaction mixture was kept at 273 K. An aqueous solution (1 mL) of NaNO2 (151.8 mg, 2.2 mmol) was added dropwise to generate the azonium intermediate, and the reaction mixture was stirred for 10 min. A solution of 3-bromoaniline (0.260 g, 2.2 mmol) and sodium hydroxide (0.150 g) in MeOH-H2O (2:1, v/v, 9 mL) was kept at 273 K. With stirring, the azonium intermediate was added dropwise to the 3-bromoaniline solution while maintaining the temperature at 273 K. After stirring for 2 h at room temperature, water (50 mL) was added to induce precipitation of an orange solid, which was isolated by filtration and washed with water, and dried. Flash column chromatography on silica gel, eluted with hexane-EtOAc (5:1, v/v), gives a solid (513.3 mg, yield 51.7%) which was recrystallized from acetone to give orange plates.

Experimental details

H atoms were included in calculated positions and refined using a riding model, with C—H distances, O—H distances, N—H distances constrained to 0.95–0.98 Å, 0.84 Å and 0.88 Å, respectively, and with Uiso(H) = 1.2Ueq(C).

Discussion

Cinnoline derivatives are an important class of heterocyclic compounds showing important biological activities [2]. In recent years, a large number of cinnoline compounds were found to own interesting pharmacological properties including anticancer [3], anti-inflammatory and antibacterial [4].

There are two crystallographically independent molecules in the asymmetric unit, which are slightly different concerning their conformation. All bond lengths and angles are in the expected ranges. There are intramolecular hydrogen bonding N—H⋯O interactions and intermolecular hydrogen bonding O—H⋯O and weak O—H⋯Br interactions in the crystal structure.

Funding source: Shanxi Scholarship Council of China

Award Identifier / Grant number: 20090980

Funding statement: The work was supported by the National Nature Science Foundation of China (21175085, 21375083, and 21106044) and by the Shanxi Scholarship Council of China (20090980)

Acknowledgements:

The work was supported by the National Nature Science Foundation of China (21175085, 21375083, and 21106044) and by the Shanxi Scholarship Council of China (20090980).

References

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2. Tonk, R. K.; Bawa, S.; Chawla, G.; Deora, G. S.; Kumar, S.; Rathore, V.; Mulakayala, N.; Rajaram, A.; Kalle, A. M.; Afzal, O.: Synthesis and pharmacological evaluation of pyrazolo 4,3-c cinnoline derivatives as potential anti-inflammatory and antibacterial agents. Eur. J. Med. Chem. 57 (2012) 176–184.10.1016/j.ejmech.2012.08.045Search in Google Scholar PubMed

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Received: 2016-5-13
Accepted: 2016-8-8
Published Online: 2016-9-17
Published in Print: 2016-12-1

©2016 Yue-Hua Yuan et al., published by De Gruyter.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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  46. Crystal structure of dimethanolo-bis[μ-(2-(2-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)phenoxy)benzoato)-κ5O,O′,N:N′,N′′]dicopper(II) — methanol (1/2), C46H48Cu2N8O12
  47. Crystal structure of poly-[tetraaqua-bis(μ4-2,5-dibenzoyl-1,4-benzenedicarboxylato-κ4O1:O2:O3:O4)-μ2-2,5-dibenzoyl-1,4-benzenedicarboxylato-k4O5,O6: O5′,O6′-didysprosium(III)] tetrahydrate C33H26O13Dy
  48. Crystal structure of hexaaqua-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl) propionato-κ3O,O′:O′)-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl)propionato-κO)-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl)propionato-κ2O,O′)dineodymium(III) octahydrate, C60H76N18O32Nd2
  49. Crystal structure of poly-[triaqua-(μ3-3,4,5,6-tetrafluoro-1,2-phthalato-κ4O:O′:O′′,O′′′) (2,3,4,5-tetrafluoro-benzoato-κ2O,O′) praseodymium(III)], C15H7F8O9Pr
  50. The crystal structure of dichlorido (1,3-dimesityl-1H-3λ4-imidazol-2-yl)(isoquinoline-κN)palladium(IV) – ethylacetate (1/1), C34H39Cl2N3O2Pd
  51. Crystal structure of dichlorido(1,3-bis(2,6-dimethyl-phenyl)-1H-3λ4-imidazol-2-yl)(isoquinolinyl)palladium(IV), C28H27Cl2N3Pd
  52. Crystal structure of 5-(4-(1H-tetrazol-5-yl)phenyl)-1H-imidazol-3-ium 7-carboxy-1,3-dioxo-1H,3H-benzo[de]isochromene-6-carboxylate monohydrate 4,5-anhydride, C24H16N6O8
  53. Crystal structure of poly-[diaqua-bis(μ2-2-((1H-1,2,4-triazol-5-yl)thio)acetato-κ2N:O) cadmium(II)], C8H8CdN6O6S2
  54. Crystal Structure of (E)-3-(4-methoxyphenyl)-1-(2,3,4-tris(benzyloxy)-6-hydroxyphenyl)prop-2-en-1-one, C37H32O6
  55. Structure and photochromism of 1-(1,2-dimethylindol-3-yl)-2-[2-methyl-5-(3-fluorophenyl)-3-thienyl]-3,3,4,4,5,5-hexafluorocyclopent-1-ene, C26H18F7NS
  56. Crystal structure of two-dimensional coordination polymer poly-[μ2-azido-aqua-(μ2-pyrazine-2-carboxylato-κ3O,N:N′)nickel(II)], C5H5N5O3Ni
  57. Crystal structure of 2-amino-5-oxo-4-(3,5-bis(trifluoromethyl)phenyl)-4H,5H-pyrano [3,2-c]chromene-3-carbonitrile, C21H10F6N2O3
  58. Crystal structure of 4-(5-((2-methylbenzyl)thio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine, C21H18N4S
  59. Crystal structure of 5-(2-chloro-5-nitrophenyl)-3-(4-chlorophenyl)-N-ethyl-4,5-dihydro-1H-pyrazole-1-carbothioamide, C18H16Cl2N4O2S
  60. Crystal structure of 4-(benzofuran-2-yl)-2-(3-(4-fluorophenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl)thiazole, C28H20FN3OS
  61. Crystal structure of bis(dicyanamido-κ1N)-tetrakis[1-benzyl-1H-1,2,4-triazole-κ1N]cobalt(II), CoC40H36N18
  62. Crystal structure of 1-benzyl-6-hydroxy-1,4,5,6-tetrahydropyridine-3-carbonitrile, C13H14N2O
  63. Crystal structure of 2-amino-7-methyl-4-(3,4-difluoro-phenyl)-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile, C16H10F2N2O3
  64. The crystal structure of 4-[(benzo[1,3]dioxol-5-ylmethylene)-amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one, C19H17N3O3
  65. Crystal structure of 1,4-dihydro-1-phenylchromeno[4,3-c]pyrazole, C16H12N2O
  66. Crystal structure of N-(5-((3,5-dimethylisoxazol-4-yl)sulfonyl)quinolin-8-yl)benzamide, C21H17N3O4S
  67. Crystal structure of 3-amino-9-methoxy-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, C21H16N2O2
  68. Crystal structure of 1,2-bis(4-methoxyphenyl)-2-((3-(trifluoromethyl)phenyl)amino)ethan-1-one, C23H20F3NO3
  69. Crystal structure of 2-amino-4-(2,4-dinitrophenyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile – ethanol (1:1), C21H16N4O8
  70. Crystal structure of catena-poly-[(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-ium-1-yl)-1,4-dihydroquinoline-3-carboxylate-κ2O,O′)-(μ2-4,4′-sulfonyldibenzoato-κ4O,O′:O′′,O′′′)zinc(II)] hemihydrate, C31H27ZnFN3O9.5S
  71. Crystal structure of 2-(2-bromophenyl)-5-methyl-1,3-dioxane-5-carboxylic acid, C12H13BrO4
  72. Crystal structure of 2-(2-bromophenyl)-5-ethyl-1,3-dioxane-5-carboxylic acid, C13H15BrO4
  73. Crystal structure of 4-(4-((3-bromophenyl)amino)-6-(tert-butyl)-3-(2-hydroxypropan-2-yl)cinnolin-8-yl)-2-methylbut-3-yn-2-ol, C26H30BrN3O2
  74. Crystal structure poly-(μ2-1-(4-(1H-imidazol-1-yl)benzyl)-1H-1,2,4-triazolyl-κ2NN1:N2N)-(μ3-2,2′-(1,2-phenylene)diacetato-κ5-O1,O2:O2:O3,O4)cadmium(II), C22H19CdN5O4
  75. Crystal structure of bis(1-ethyl-6-fluoro-4-oxido-7-(piperazin-1-ium-1-yl)-1,8-naphthyridin-1-ium-3-carboxylate-κ2O,O′)copper(II) benzene-1, 4-dicarboxylate dihydrate, C38H42F2CuN8O12
  76. Redetermination of the crystal structure of potassium lithium molybdate monohydrate, KLiMoO4·H2O
  77. Crystal structure of [tris(2-benzimidazolylmethyl)amine-κ3N](isonicotinate-κO) cobalt(II) [tris(2-benzimidazolylmethyl)amine-κ3N](isonicotinic acid-κO) cobalt(II) triperchlorate, C60H51N16O16Cl3Co2
  78. The crystal structure of tris(μ2-1,3-bis(4,4,4-trifluoro-3-oxido-1-(oxo)but-2-en-1-yl)phenyl-κ4O,O′:O′′,O′′′)-bis(1,2-dimethoxyethane-κ2O,O′)dicerium(III), C50H38F18O16Ce2
  79. Crystal structure of 8-isopropyl-8-aza-bicyclo[3.2.1]octan-3-ol, C10H19NO
  80. Crystal structure of 2,4-dibenzoyl-N,N-dimethylbenzenamine, C22H19NO2
  81. The crystal structure of 2-(4-methoxyphenyl)-6,8-diphenyl-4-(phenylamino)quinazoline — acetonitrile (1/1), C35H28N4O
https://doi.org/10.1515/ncrs-2016-0138
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Articles in the same Issue

  1. Cover and Frontmatter
  2. Crystal structure of the catena-poly-[bis(μ2-1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl-κN)-1,4-dihydroquinoline-3-carboxylato-κ2O,O′)nickel(II)] 5.5 hydrate, C32H44N6NiO11F2
  3. Crystal structure of catena-poly-[(μ2-2-(2-((2,6-dimethylphenyl)amino)phenyl)acetato-κ2O:O′)(μ2-2-(2-((2,6-dimethylphenyl)amino)phenyl)acetate-κ3O,O′:O′)cadmium(II)], C28H20N2Cl4O4Cd
  4. Crystal structure of catena-poly[dichlorido-(μ2-4-(pyridin-4-yl)-isophthalate-κ2O, O′)cadmium(II)] monohydrate, C13H11NO5Cl2Cd
  5. Crystal structure of poly-{[μ2-(E)-1,4-di(1H-imidazol-1-yl)but-2-ene-κ2N:N′][μ2-cyclohexane-1,4-dicarboxylato-κ4O,O′:O′′,O′′′]nickel(II)}, C18H22N4NiO4
  6. Crystal structure of aqua (5,5′-dicarboxy-(1,1′-biphenyl)-2,3′-dicarboxylato-κO) bis(1,10-phenanthroline-κ2N,N′)cadmium monohydrate, C40H28CdN4O10
  7. Crystal structure of 5-methoxy-N′-[(3Z)-5-chloro-1-(4-fluorobenzyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-1H-indole-2-carbohydrazide-DMSO (1/1), C25H18ClFN4O3 · C2H6OS
  8. Crystal structure of 5-methoxy-N′-[(3Z)-1-benzyl-5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-1H-indole-2-carbohydrazide-DMSO (1/1), C27H25FN4O4S
  9. Crystal structure of poly-[bis{μ2-N-(4-(1H-imidazol-1-yl)phenyl)-4-(1H-imidazol-1-yl)-N-phenylaniline-κ2N:N′)}-(μ2-naphthalene-2,6-dicarboxylato)-(μ4-naphthalene-2,6-dicarboxylato)dicadmium(II)], C36H25N5O4Cd
  10. Crystal structure of 1-(adamantan-1-yl)-3-(4-bromophenyl)thiourea, C17H21BrN2S
  11. Crystal structure of N′-[(1E)-(2,6-dichlorophenyl)-methylidene]adamantane-1-carbohydrazide, C18H20Cl2N2O
  12. Crystal structure of dichlorido{bis(2-hydroxyethyl)-5′-([2,2′:6′,2′′-terpyridin]-4′-yl)-[1,1′:3′,1′′-terphenyl]-4,4′′-dicarboxylate-κ3N,N′,N′′}zinc(II), C39H31Cl2N3O6Zn
  13. Crystal structure of 4,4′-(1,3,5,7-tetraoxo-3a,4,4a,5,7,7a,8,8a-octahydro-4,8-ethenopyrrolo [3,4-f]isoindole-2,6(1H,3H)-diyl)dibenzoic acid, C26H18N2O8
  14. Crystal structure of (E)-1-(4-(((E)-3,5-dichloro-2-hydroxybenzylidene)amino)phenyl)ethan-1-one O-ethyl oxime, C17H16Cl2N2O2
  15. The crystal structure of diaqua-(N-(2-hydroxy-5-nitrobenzyl)iminodiacetato-κ4-N,O,O′,O′′)chromium(III) based on synchrotron data, C11H13CrN2O9
  16. Crystal structure of ethyl 5-amino-3-(methylthio)-1-(1-phenyl-5-(thiophen-2-yl)-1H-pyrazole-3-carbonyl)-1H-pyrazole-4-carboxylate, C21H19N5O3S2
  17. Crystal structure of (E)-1-(4-(((E)-3,5-dibromo-2-hydroxybenzylidene)amino)phenyl)ethan-1-one O-methyl oxime, C17H16Br2N2O2
  18. Crystal structure of dibromido μ-oxalato-κ2O,O′:κ2O′′,O′′′−η6-p-cymenediosmium(II), C22H28Br2O4Os2
  19. Crystal structure of 2-(bromomethyl)-4-(4-chlorophenyl)-1-tosylpyrrolidine, C18H19BrClNO2S2
  20. Crystal structure of 5-(3-fluorobenzylidene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; C13H11FN2O3
  21. Crystal structure of diethylammonium 1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-ide, C10H19N3O3
  22. Crystal structure of 1,1-dimethyl-3-(2-phenylethyl)urea, C11H16N2O
  23. Crystal structure of 2-(4-methoxyphenyl)-1,3-thiazolo[4,5-b]pyridine, C13H10N2OS
  24. Crystal structure of 3-tert-butyl-7-azadioxindole, C11H14N2O2
  25. Crystal structure of 1-ferrocenyl-6-bromopyrene, C26H17BrFe
  26. Crystal structure of 3-(4-bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide, C16H13BrFN3S
  27. Crystal structure of 2-amino-4-(3,5-ditrifluoromethylphenyl)-3-cyano-7,7-dimethyl-5-oxo-4H-5,6,7,8-tetrahydrobenzo[b]pyran, C20H16F6N2O2
  28. The crystal structure of 2-amino-4-(4-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile, C16H13N3O4
  29. Crystal structure of 2-amino-4-(2, 4-dichlorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile, C16H12Cl2N2O2
  30. Crystal structure of bis(μ2-chlorido)-bis(di-p-tolylhydroxyphosphine-κP)-bis(di-p-tolylphosphite-κP)dipalladium(II), C56H58Cl2O4P4Pd2
  31. Crystal structure of diaqua-bis(2-methyl-1H-imidazole-4,5-dicarboxylato-κ2-O,N)cadmium(II) tetrahydrate, C12H22CdN4O14
  32. Crystal structure of aqua-(5-nitrosalicylato-κ2O,O′)-(1,10-phenanthroline-κ2N,N′)copper(II), C19H13CuN3O6
  33. Crystal structure of bis(4-(2-phenylpropan-2-yl)phenyl)amine, C30H31N
  34. Crystal structure of 2-amino-4-(3,5-difluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile, C18H16F2N2O2
  35. Crystal structure of 2-amino-4-(3,4,5-trifluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile, C16H11F3N2O2
  36. Crystal structure of an isomeric bis[(η5:η1-6,6-di-p-tolylpentafulvene)(η5-pentamethylcyclopentadienyl)titanium(III)]-μ2,η1:η1-dinitrogen complex, C60H66N2Ti2
  37. Crystal structure of 3,4-dinitropyrazole, C3H2N4O4
  38. Crystal structure of (4-vinylpyridine-κN)triphenyl tin(IV) chloride, C25H22ClNSn
  39. Crystal structure of tert-butyl 2-phenylethylcarbamate, C13H19NO2
  40. Crystal structure of (Z)-4-((E)-(4-chlorobenzyli-dene)hydrazono)-1-p-tolylpyrrolidine-3-carbonitrile, C19H17ClN4
  41. Crystal structure of bis(biphenyl-2,2′-dicarboxylato-κ2O:O′)-bis(1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylato-κ2O,O′)dizinc(II)2.5 hydrate, C62H57N6Zn2O16.5F2
  42. Crystal structure of dichloridobis{μ2-2,2′-((1E,1′E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))bis(4-chlorophenolato)-κ5O,N,N′,O′:O′}diiron(III), C32H24Cl6Fe2N4O4
  43. Crystal structure of 4-((4,4-dimethyl-2, 6-dioxocyclohexylidine)methylamino)-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide, C20H23N3O5S
  44. Crystal structure of poly-[aqua-μ2-aqua-μ2-(4,4′-oxybis(benzoato)-κ4O,O′:O′′,O′′′)cadmium(II)], C14H12O7Cd
  45. Crystal structure of aqua(μ2-biphenyl-2,2′-dicarboxylato-κ3O,O′:O′′)-(μ2-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylato-κ2O,O′)cadmium(II) 1.5 hydrate, C62H60N6Cd2O19F2
  46. Crystal structure of dimethanolo-bis[μ-(2-(2-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)phenoxy)benzoato)-κ5O,O′,N:N′,N′′]dicopper(II) — methanol (1/2), C46H48Cu2N8O12
  47. Crystal structure of poly-[tetraaqua-bis(μ4-2,5-dibenzoyl-1,4-benzenedicarboxylato-κ4O1:O2:O3:O4)-μ2-2,5-dibenzoyl-1,4-benzenedicarboxylato-k4O5,O6: O5′,O6′-didysprosium(III)] tetrahydrate C33H26O13Dy
  48. Crystal structure of hexaaqua-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl) propionato-κ3O,O′:O′)-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl)propionato-κO)-bis(3-(3-pyridin-4-yl-[1,2,4]oxadiazol-5-yl)propionato-κ2O,O′)dineodymium(III) octahydrate, C60H76N18O32Nd2
  49. Crystal structure of poly-[triaqua-(μ3-3,4,5,6-tetrafluoro-1,2-phthalato-κ4O:O′:O′′,O′′′) (2,3,4,5-tetrafluoro-benzoato-κ2O,O′) praseodymium(III)], C15H7F8O9Pr
  50. The crystal structure of dichlorido (1,3-dimesityl-1H-3λ4-imidazol-2-yl)(isoquinoline-κN)palladium(IV) – ethylacetate (1/1), C34H39Cl2N3O2Pd
  51. Crystal structure of dichlorido(1,3-bis(2,6-dimethyl-phenyl)-1H-3λ4-imidazol-2-yl)(isoquinolinyl)palladium(IV), C28H27Cl2N3Pd
  52. Crystal structure of 5-(4-(1H-tetrazol-5-yl)phenyl)-1H-imidazol-3-ium 7-carboxy-1,3-dioxo-1H,3H-benzo[de]isochromene-6-carboxylate monohydrate 4,5-anhydride, C24H16N6O8
  53. Crystal structure of poly-[diaqua-bis(μ2-2-((1H-1,2,4-triazol-5-yl)thio)acetato-κ2N:O) cadmium(II)], C8H8CdN6O6S2
  54. Crystal Structure of (E)-3-(4-methoxyphenyl)-1-(2,3,4-tris(benzyloxy)-6-hydroxyphenyl)prop-2-en-1-one, C37H32O6
  55. Structure and photochromism of 1-(1,2-dimethylindol-3-yl)-2-[2-methyl-5-(3-fluorophenyl)-3-thienyl]-3,3,4,4,5,5-hexafluorocyclopent-1-ene, C26H18F7NS
  56. Crystal structure of two-dimensional coordination polymer poly-[μ2-azido-aqua-(μ2-pyrazine-2-carboxylato-κ3O,N:N′)nickel(II)], C5H5N5O3Ni
  57. Crystal structure of 2-amino-5-oxo-4-(3,5-bis(trifluoromethyl)phenyl)-4H,5H-pyrano [3,2-c]chromene-3-carbonitrile, C21H10F6N2O3
  58. Crystal structure of 4-(5-((2-methylbenzyl)thio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine, C21H18N4S
  59. Crystal structure of 5-(2-chloro-5-nitrophenyl)-3-(4-chlorophenyl)-N-ethyl-4,5-dihydro-1H-pyrazole-1-carbothioamide, C18H16Cl2N4O2S
  60. Crystal structure of 4-(benzofuran-2-yl)-2-(3-(4-fluorophenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl)thiazole, C28H20FN3OS
  61. Crystal structure of bis(dicyanamido-κ1N)-tetrakis[1-benzyl-1H-1,2,4-triazole-κ1N]cobalt(II), CoC40H36N18
  62. Crystal structure of 1-benzyl-6-hydroxy-1,4,5,6-tetrahydropyridine-3-carbonitrile, C13H14N2O
  63. Crystal structure of 2-amino-7-methyl-4-(3,4-difluoro-phenyl)-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile, C16H10F2N2O3
  64. The crystal structure of 4-[(benzo[1,3]dioxol-5-ylmethylene)-amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one, C19H17N3O3
  65. Crystal structure of 1,4-dihydro-1-phenylchromeno[4,3-c]pyrazole, C16H12N2O
  66. Crystal structure of N-(5-((3,5-dimethylisoxazol-4-yl)sulfonyl)quinolin-8-yl)benzamide, C21H17N3O4S
  67. Crystal structure of 3-amino-9-methoxy-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, C21H16N2O2
  68. Crystal structure of 1,2-bis(4-methoxyphenyl)-2-((3-(trifluoromethyl)phenyl)amino)ethan-1-one, C23H20F3NO3
  69. Crystal structure of 2-amino-4-(2,4-dinitrophenyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile – ethanol (1:1), C21H16N4O8
  70. Crystal structure of catena-poly-[(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-ium-1-yl)-1,4-dihydroquinoline-3-carboxylate-κ2O,O′)-(μ2-4,4′-sulfonyldibenzoato-κ4O,O′:O′′,O′′′)zinc(II)] hemihydrate, C31H27ZnFN3O9.5S
  71. Crystal structure of 2-(2-bromophenyl)-5-methyl-1,3-dioxane-5-carboxylic acid, C12H13BrO4
  72. Crystal structure of 2-(2-bromophenyl)-5-ethyl-1,3-dioxane-5-carboxylic acid, C13H15BrO4
  73. Crystal structure of 4-(4-((3-bromophenyl)amino)-6-(tert-butyl)-3-(2-hydroxypropan-2-yl)cinnolin-8-yl)-2-methylbut-3-yn-2-ol, C26H30BrN3O2
  74. Crystal structure poly-(μ2-1-(4-(1H-imidazol-1-yl)benzyl)-1H-1,2,4-triazolyl-κ2NN1:N2N)-(μ3-2,2′-(1,2-phenylene)diacetato-κ5-O1,O2:O2:O3,O4)cadmium(II), C22H19CdN5O4
  75. Crystal structure of bis(1-ethyl-6-fluoro-4-oxido-7-(piperazin-1-ium-1-yl)-1,8-naphthyridin-1-ium-3-carboxylate-κ2O,O′)copper(II) benzene-1, 4-dicarboxylate dihydrate, C38H42F2CuN8O12
  76. Redetermination of the crystal structure of potassium lithium molybdate monohydrate, KLiMoO4·H2O
  77. Crystal structure of [tris(2-benzimidazolylmethyl)amine-κ3N](isonicotinate-κO) cobalt(II) [tris(2-benzimidazolylmethyl)amine-κ3N](isonicotinic acid-κO) cobalt(II) triperchlorate, C60H51N16O16Cl3Co2
  78. The crystal structure of tris(μ2-1,3-bis(4,4,4-trifluoro-3-oxido-1-(oxo)but-2-en-1-yl)phenyl-κ4O,O′:O′′,O′′′)-bis(1,2-dimethoxyethane-κ2O,O′)dicerium(III), C50H38F18O16Ce2
  79. Crystal structure of 8-isopropyl-8-aza-bicyclo[3.2.1]octan-3-ol, C10H19NO
  80. Crystal structure of 2,4-dibenzoyl-N,N-dimethylbenzenamine, C22H19NO2
  81. The crystal structure of 2-(4-methoxyphenyl)-6,8-diphenyl-4-(phenylamino)quinazoline — acetonitrile (1/1), C35H28N4O
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