The effects of intramuscular administration of corticosteroids on the induction of parturition
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S. Ziaei
Abstract
Our purpose was to examine the hypothesis that corticosteroids, when administered intramuscularly, can enhance the labor process and reduce the time interval between the induction and the active phase.
A randomized, controlled study was conducted on 66 women with gestational age of 41 weeks and over and favorable cervix (bishop score ≥ 7).
The study group (n = 32) received 10mg of dexamethasone phosphate intramuscularly in two doses at an interval of 12 hours, and the day after the enrolling administration intravenous oxytocin was given. The control group (n = 33) received only intravenous oxytocin 24 hours after enrolling.
The number of patients to enter the active phase of labor was significantly higher in the study group than in the control group (n = 33 [100%] vs n = 29 [87.9%], p < 0.039). The mean time interval between induction of labor and the active phase was significantly shorter in the study group than in the control group (1.7±1.5 hours vs 4±1.7, P < 0.0001), and the mean of oxytocin dose was significantly lower in the study group (1.15±1.5u vs 4.16±2.5u, P < 0.0001).
Induction of labor with the use of intramuscularly injected dexamethasone phosphate reduced the time interval between the induction of labor and the active phase.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
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- Mode of conception, placental morphology and perinatal outcome of twin gestations
- The effects of birth weight discordance and prematurity on twin neonatal outcome
- Esophageal atresia and tracheoesophageal fistula: the impact of prenatal suspicion on neonatal outcome in a tertiary care center
- Microbial invasion of the amniotic cavity at birth is associated with adverse short-term outcome of preterm infants
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- The effects of intramuscular administration of corticosteroids on the induction of parturition
- Perinatal significance of diagnosing glucose intolerance during pregnancy with portable glucose meter
- Biovar diversity of Ureaplasma urealyticum in amniotic fluid: distribution, intrauterine inflammatory response and pregnancy outcomes
- Comparative study on the expression of cytokine – receptor genes in normal and preeclamptic human placentas using DNA microarrays
- Chorioangioma – new insights into a well-known problem I. Results of a clinical and morphological study of 136 cases
- Chorioangiomas – new insights into a well-known problem II. An immuno-histochemical investigation of 136 cases
- Impaired CD14-dependent and independent response of polymorphonuclear leukocytes in preterm infants
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- Congress Calendar
