Esophageal atresia and tracheoesophageal fistula: the impact of prenatal suspicion on neonatal outcome in a tertiary care center
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R. B. Kalish
Abstract
Aims: To determine the impact of antenatal suspicion of esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) on neonatal outcome.
Methods: Retrospective review of all neonates with EA who received prenatal care including fetal ultrasound and delivery at our institution from 1990–2001. Cases with suspected EA on prenatal ultrasound (hydramnios and/or an absent stomach bubble) were identified. Neonatal outcome variables for the group suspected antenatally and the group diagnosed postnatally were compared. Mann Whitney U and Fischer exact tests were used in analysis.
Results: Twenty-two patients met inclusion criteria. Nine cases (40.9%) had prenatal ultrasound findings associated with EA/TEF. There was no statistically significant difference in the incidence of preterm delivery, intrauterine growth restriction, respiratory distress syndrome, additional anomalies or neonatal death, birth weight, requirement for preoperative and postoperative mechanical ventilation or length of hospital stay between the prenatally suspected and postnatally diagnosed groups. There were two neonatal demises: one had trisomy 18 and one was born prematurely at 29 weeks.
Conclusions: In our experience, prenatal detection of ultrasound findings associated with EA/TEF does not affect neonatal outcome or identify a group at increased risk for neonatal morbidity and mortality. Our favorable outcomes, with or without prenatal suspicion, may reflect the comprehensive care readily available at a tertiary care facility. Larger series need to be studied to exclude the possibility of a type II error.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- Mode of conception, placental morphology and perinatal outcome of twin gestations
- The effects of birth weight discordance and prematurity on twin neonatal outcome
- Esophageal atresia and tracheoesophageal fistula: the impact of prenatal suspicion on neonatal outcome in a tertiary care center
- Microbial invasion of the amniotic cavity at birth is associated with adverse short-term outcome of preterm infants
- Is treatment with vaginal pessaries an option in patients with a sonographically detected short cervix?
- The effects of intramuscular administration of corticosteroids on the induction of parturition
- Perinatal significance of diagnosing glucose intolerance during pregnancy with portable glucose meter
- Biovar diversity of Ureaplasma urealyticum in amniotic fluid: distribution, intrauterine inflammatory response and pregnancy outcomes
- Comparative study on the expression of cytokine – receptor genes in normal and preeclamptic human placentas using DNA microarrays
- Chorioangioma – new insights into a well-known problem I. Results of a clinical and morphological study of 136 cases
- Chorioangiomas – new insights into a well-known problem II. An immuno-histochemical investigation of 136 cases
- Impaired CD14-dependent and independent response of polymorphonuclear leukocytes in preterm infants
- The left portal vein is the watershed of the fetal venous system
- Congress Calendar
