Edge Effect in Hot Embossing and its Influence on Global Pattern Replication of Polymer-Based Microneedles

References

Ames, N. M., “Chapter 5 A Thermo-Mechanical Finite Deformation Theory of Plasticity for Amorphous Polymers: Application to Micro-Hot-Embossing of Poly(methyl methacrylate)”, in A Thermo-Mechanical Finite Deformation Theory of Plasticity for Amorphous Polymers: Application to Micro-Hot-Embossing of Poly(methyl methacrylate), PhD Thesis, Massachusetts Institute of Technology, Cambridge, MA, USA (2007)Suche in Google Scholar

Cha, K. J., Kim, T., Park, S. J. and Kim, D. S., “Simple and Cost-Effective Fabrication of Solid Biodegradable Polymer Microneedle Arrays with Adjustable Aspect Ratio for Transdermal Drug Delivery Using Acupuncture Microneedles”, J. Micromech. Microeng., 24, 115015 (2014) 10.1088/0960-1317/24/11/115015Suche in Google Scholar

Chang, L.-Q., Bertani, P., Gallego-Perez, D., Yang, Z._G., Chen, F., Chiang, C.-L., Malkoc, V., Kuang, T.-R., Gao, K.-L., Lee, L. J. and Lu, W., “3D Nanochannel Electroporation for High-Throughput Cell Transfection with High Uniformity and Dosage Control”, Nanoscale, 8, 243–252 (2016)PMid:26309218; 10.1039/C5NR03187GSuche in Google Scholar PubMed

Chen, X., Zhang, Z. and Gao, Q., “PMMA Micro-Pillar Forming in Micro Channel by Hot Embossing”, Int. Polym. Proc., 31, 364–368 (2016) 10.3139/217.3207Suche in Google Scholar

De Santis, F., Pantani, R., “Development of a Rapid Surface Temperature Variation System and Application to Micro-Injection Molding”, J. Mater. Process. Technol., 237, 1–11 (2016) 10.1016/j.jmatprotec.2016.05.023Suche in Google Scholar

Donnelly, R. F., Singh, T. R. R. and Woolfson, A. D., “Microneedle-Based Drug Delivery Systems: Microfabrication, Drug Delivery, and Safety”, Drug Delivery, 17, 187–207 (2010)PMid:20297904; 10.3109/10717541003667798Suche in Google Scholar PubMed PubMed Central

Gomez, J. A., Conner, G. T., Chun, D. H., Kim, Y.-J., Song, I.-H. and You, B. H., “Mold Filling Analysis of an Alignment Structure in Micro Hot Embossing”, Fibers Polym., 15, 1197–1201 (2014) 10.1007/S12221-014-1197-5Suche in Google Scholar

Han, M., Hyun, D.-H., Park, H.-H., Lee, S. S., Kim, C.-H. and Kim, C.-G., “A Novel Fabrication Process for Out-Of-Plane Microneedle Sheets of Biocompatible Polymer”, J. Micromech. Microeng., 17, 1184–1191 (2007) 10.1088/0960-1317/17/6/012Suche in Google Scholar

Han, M., Kim, D. K., Kang, S. H., Yoon, H.-R., Kim, B.-Y., Lee, S. S., Kim, K. D. and Lee, H. G., “Improvement in Antigen-Delivery Using Fabrication of a Grooves-Embedded Microneedle Array”, Sens. Actuators, B, 137, 274–280 (2009) 10.1016/j.snb.2008.11.017Suche in Google Scholar

He, Y., Fu, J.-Z., Zhao, P. and Chen, Z. C., “Enhanced Polymer Filling and Uniform Shrinkage of Polymer and Mold in a Hot Embossing Process”, Polym. Eng. Sci., 53, 1314–1320 (2013) 10.1002/pen.23379Suche in Google Scholar

Jha, J. S., Joshi, S. S., “Numerical Simulation of Micro Hot Embossing of Polymer Substrate”, Int. J. Precis. Eng. Manuf., 13, 2215–2224 (2012) 10.1007/s12541-012-0294-xSuche in Google Scholar

Juang, Y.-J., Lee, L. J. and Koelling, K. W., “Hot Embossing in Microfabrication. Part II: Rheological Characterization and Process Analysis”, Polym. Eng. Sci., 42, 551–566 (2002) 10.1002/pen.10971Suche in Google Scholar

Kim, Y.-C., Park, J.-H. and Prausnitz, M. R., “Microneedles for Drug and Vaccine Delivery”, Adv. Drug Delivery Rev., 64, 1547–1568 (2012)PMid:22575858; 10.1016/j.addr.2012.04.005Suche in Google Scholar PubMed PubMed Central

Kuang, T.-R., Chang, L.-Q., Peng, X.-F., Hu, X.-L. and Gallego-Perez, D., “Molecular Beacon Nano-Sensors for Probing Living Cancer Cells”, Trends Biotechnol., 35, 347–359 (2017)PMid:27692896; 10.1016/j.tibtech.2016.09.003Suche in Google Scholar PubMed

Lee, J. W., Park, J.-H. and Prausnitz, M. R., “Dissolving Microneedles for Transdermal Drug Delivery”, Biomaterials, 29, 2113–2124 (2008)PMid:18261792; 10.1016/j.biomaterials.2007.12.048Suche in Google Scholar PubMed PubMed Central

Mansoor, I., Liu, Y., Häfeli, U. O. and Stoeber, B., “Arrays of Hollow Out-Of-Plane Microneedles Made by Metal Electrodeposition onto Solvent Cast Conductive Polymer Structures”, J. Micromech. Microeng., 23, 085011 (2013) 10.1088/0960-1317/23/8/085011Suche in Google Scholar

Ochoa, M., Mousoulis, C., Ziaie, B., “Polymeric Microdevices for Transdermal and Subcutaneous Drug Delivery”, Adv. Drug Delivery Rev., 64, 1603–1616 (2012)PMid:23000744; 10.1016/j.addr.2012.09.035Suche in Google Scholar PubMed

Park, J. H., Allen, M. G. and Prausnitz, M. R., “Polymer Microneedles for Controlled-Release Drug Delivery”, Pharm. Res., 23, 1008–1019 (2006)PMid:16715391; 10.1007/s11095-006-0028-9Suche in Google Scholar PubMed

Peng, L. F., Deng, Y.-J., Yi, P.-Y. and Lai, X.-M., “Micro Hot Embossing of Thermoplastic Polymers: A Review”, J. Micromech. Microeng., 24, 013001 (2014) 10.1088/0960-1317/24/1/013001Suche in Google Scholar

Pettis, R. J., Harvey, A. J., “Microneedle Delivery: Clinical Studies and Emerging Medical Applications”, Therapeutic Delivery, 3, 357–371 (2012)PMid:22833995; 10.4155/tde.12.13Suche in Google Scholar PubMed

Prausnitz, M. R., “Microneedles for Transdermal Drug Delivery”, Adv. Drug Delivery Rev., 56, 581–587 (2004)PMid:15019747; 10.1016/j.addr.2003.10.023Suche in Google Scholar PubMed

Sha, L.-L., Chen, Z.-F., Chen, Z., Zhang, A.-L. and Yang, Z.-G., “Polylactic Acid Based Nanocomposites: Promising Safe and Biodegradable Materials in Biomedical Field”, Int. J. Polym. Sci., 1–11 (2016) 10.1155/2016/6869154Suche in Google Scholar

Shukla, V. C., Kuang, T.-R., Senthilvelan, A., Higuita-Castro, N., Duarte-Sanmiguel, S., Ghadiali, S. N. and Gallego-Perez, D., “Lab-On-A-Chip Platforms for Biophysical Studies of Cancer with Single-Cell Resolution”, Trends Biotechnol., 36, 549–561 (2018)PMid:29559164; 10.1016/j.tibtech.2018.02.007Suche in Google Scholar PubMed

Sun, J.-Y., Shen, J.-J., Chen, S.-K., Cooper, M. A., Fu, H.-B., Wu, D.-M. and Yang, Z.-G., “Nanofiller Reinforced Biodegradable PLA/PHA Composites: Current Status and Future Trends”, Polymers, 10, 505 (2018a) 10.3390/polym10050505Suche in Google Scholar PubMed PubMed Central

Sun, J.-Y., Wang, X.-B., Wu, J.-H., Jiang, C., Shen, J.-J., Cooper, M. A., Zheng, X.-T., Liu, Y., Yang, Z.-G. and Wu, D.-M., “Biomimetic Moth-Eye Nanofabrication: Enhanced Antireflection with Superior Self-Cleaning Characteristic”, Scientific Reports, 8, 5438 (2018b) 10.1038/s41598-018-23771-ySuche in Google Scholar PubMed PubMed Central

Sun, J.-Y., Wu, D.-M., Liu, Y., Dai, L. and Jiang, C., “Numerical Simulation and Experimental Study of Filling Process of Micro Prism by Isothermal Hot Embossing in Solid-Like State”, Adv. Polym. Technol., 37, 1581–1591 (2017) 10.1002/adv.21815Suche in Google Scholar

Sun, J., J.-Y., Zhao, Y.-N., Yang, Z.-G., Shen, J.-J., Cabrera, E., Lertola, M. J., Yang, W.-L., Zhang, D., Benatar, A., Castro, J. M., Wu, D.-M. and Lee, L. J., “Highly Stretchable and Ultrathin Nanopaper Composites for Epidermal Strain Sensors”, Nanotechnol., 29, 355304 (2018)PMid:29897348; 10.1088/1361-6528/aacc59Suche in Google Scholar PubMed

Sun, J.-Y., Wu, D.-M., Liu, Y., Yang, Z.-Z. and Gou, P.-S., “Rapid Fabrication of Micro Structure on Polypropylene by Plate to Plate Isothermal Hot Embossing Method”, Polym. Eng. Sci., 58, 952–960 (2018) 10.1002/pen.24651Suche in Google Scholar

Sun, J.-Y., Zhuang, J., Jiang, H., Huang, Y., Zheng, X.-T., Liu, Y. and Wu, D.-M., “Thermal Dissipation Performance of Metal-Polymer Composite Heat Exchanger with V-Shape Microgrooves: A Numerical and Experimental Study”, Appl. Therm. Eng., 121, 492–500 (2017) 10.1016/J.Applthermaleng.2017.04.104Suche in Google Scholar

Valero, A., Merino, F., Wolbers, F., Luttge, R., Vermes, I., Andersson, H. and van den Berg, A., “Apoptotic Cell Death Dynamics of HL60 Cells Studied Using a Microfluidic Cell Trap Device”, Lab on a Chip, 5, 49–55 (2005)PMid:15616740; 10.1039/B415813JSuche in Google Scholar

Van Der Maaden, K., Jiskoot, W. and Bouwstra, J., “Microneedle Technologies for (Trans)Dermal Drug and Vaccine Delivery”, J. Controlled Release, 161, 645–655 (2012)PMid:22342643; 10.1016/j.jconrel.2012.01.042Suche in Google Scholar PubMed

Wang, Y.-Q., Zhang, Q., Kuang, X.-B., Ding, Y.-C., Chen, F. and Liu, H.-Z., “Research on Hot Embossing Process of High Fill Factor Microlens Array”, Microsys. Technol., 21, 2109–2114 (2014) 10.1007/s00542-014-2352-zSuche in Google Scholar

Wu, D.-M., Sun, J.-Y., Liu, Y., Yang, Z.-Z., Xu, H., Zheng, X.-T. and Gou, P.-S., “Rapid Fabrication of Microstructure on PMMA Substrate by the Plate to Plate Transition-Spanning Isothermal Hot Embossing Method nearby Glass Transition Temperature”, Polym. Eng. Sci., 57, 268–274 (2017) 10.1002/pen.24408Suche in Google Scholar

Xie, P.-C., He, P., Yen, Y.-C., Kwak, K. J., Gallego-Perez, D., Chang, L.-Q., Liao, W.-C., Yi, A. and Lee, L. J., “Rapid Hot Embossing of Polymer Microstructures Using Carbide-Bonded Graphene Coating on Silicon Stampers”, Surf. Coat. Technol., 258, 174–180 (2014) 10.1016/j.surfcoat.2014.09.034Suche in Google Scholar

Yao, D., Virupaksha, V. L. and Kim, B., “Study on Squeezing Flow during Nonisothermal Embossing of Polymer Microstructures”, Polym. Eng. Sci., 45, 652–660 (2005) 10.1002/pen.20322Suche in Google Scholar

Zhu, X., Cui, T., “Polymer Shrinkage of Hot Embossed Microstructures for Higher Aspect Ratio and Smaller Size”, Sens. Actuators, A, 195, 21–26 (2013) 10.1016/j.sna.2013.02.015Suche in Google Scholar