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Optimal design and characterization of novel biomedical Zr-based alloys for hard tissue substitution

  • Xiaxia Gan , Hongqun Tang , Yongzhong Zhan , Jiakai Zhang , Wei Yan and Haibin Lu
Published/Copyright: July 8, 2019
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International Journal of Materials Research
From the journal International Journal of Materials Research Volume 110 Issue 7

Abstract

In this work, the quadratic regression orthogonal rotation design has been applied to optimize the composition and mechanical properties of a novel biomedical Zr-based alloy system. Combined with the statistical package for the social sciences (SPSS) analysis, a mathematical model is proposed to assess the influence of Cu, Nb and Sn contents on the elastic modulus of the alloy system. The optimal alloy composition can be determined based on the regression modeling. The experimental results exhibit the role of Nb content on mechanical properties of the Zr alloys. It is indicated that the as-cast Zr-4 at.% Cu-1.5 at.% Sn-x at.% Nb (x = 0, 7.5 and 15) alloys are mainly composed of α-Zr and Zr3Cu phases. Nb addition results in the formation of β-Zr and fine uniformly-distributed secondary phase Zr3Cu. The Zr-based alloy system exhibits low elastic modulus (19.55–32.46 GPa), moderate compression strength (1904–1117 MPa), yield strength (543–1078 MPa) and high elastic energy (7.19–18 MJ m–3). The Zr-4 at.% Cu-1.5 at.% Sn-7.5 at.% Nb alloy shows an elastic modulus of 19.55 GPa, which is comparable to that of human bones. These optimized Zr-4 at.% Cu-1.5 at.% Sn-x at.% Nb alloys can be considered as potential candidates for biological hard-tissue substitute materials.

Keywords: Optimal design; Biomedical Zr alloys; Elastic modulus; Microstructure
∗Correspondence address, Prof. Dr. Yongzhong Zhan, Prof. Dr. Hongqun Tang, College of Resources, Environment and Materials, Guangxi University, Nanning, Guangxi 530004, P.R. China, Tel: +86 771 3233530, E-mail: , E-mail:

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Received: 2018-10-04
Accepted: 2019-02-11
Published Online: 2019-07-08
Published in Print: 2019-07-15

© 2019, Carl Hanser Verlag, München

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https://doi.org/10.3139/146.111789
Keywords for this article
Optimal design; Biomedical Zr alloys; Elastic modulus; Microstructure

Articles in the same Issue

  1. Contents
  2. Contents
  3. Original Contributions
  4. 3D morphology characterization of graphite and its effect on the thermal conductivity of vermicular graphite iron
  5. Experimental liquidus studies of the Zn–Fe–Si–O system in air
  6. Phase transitions in copper–silver alloys under high pressure torsion
  7. High-temperature oxidation behavior of low sulfur martensitic stainless steel 1Cr13Mo containing cerium
  8. Microstructure and properties of Cu-bearing carbidic austempered ductile iron
  9. Fabrication of Al–WC gradient nano-composite via centrifugal casting method
  10. Properties of vacuum-laser-welded Ti-based bulk metallic glass and Zr-based bulk metallic glass composite
  11. Optimal design and characterization of novel biomedical Zr-based alloys for hard tissue substitution
  12. The influence of Mo/B atomic ratio on microstructural evolution and mechanical properties of Mo2FeB2-based cermets
  13. Piezo-spectroscopic and tribological characterization of diffusion bonded oxide laminate composite ceramics
  14. Short Communications
  15. ZnO-modified SnO flower-like microstructures with enhanced photocatalytic performance
  16. DGM News
  17. DGM News
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