Three-component, one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones catalyzed by bromodimethylsulfonium bromide
-
A. Shaabani
and
A. Maleki
Abstract
An efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives by one-pot three-component condensation reaction between an alkyl or aryl aldehyde, a 1,3-dicarbonyl compound, and urea or thiourea in the presence of catalytic amount of bromodimethylsulfonium bromide has been developed. The condensation product was obtained in excellent yields in refluxing ethanol and easily separated from the reaction mixture and purified.
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© 2007 Institute of Chemistry, Slovak Academy of Sciences
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Articles in the same Issue
- Step by step towards understanding gold glyconanoparticles as elements of the nanoworld
- Structure—activity relationships for in vitro oxime reactivation of chlorpyrifos-inhibited acetylcholinesterase
- Separation and characterization of products from thermal cracking of individual and mixed polyalkenes
- Mobility of important toxic analytes in urban dust and simulated air filters determined by sequential extraction and GFAAS/ICP-OES methods
- Effect of addition of ameliorative materials on the distribution of As, Cd, Pb, and Zn in extractable soil fractions
- Effect of gamma irradiation on trichromatic values of spices
- Homo- and heteronuclear complexes of a new, vicinal dioxime ligand
- Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interest
- Dielectric relaxation of butyl acrylate—alcohol mixtures using time domain reflectometry
- Ab initio study of small coinage metal telluride clusters AunTem (n, m = 1, 2)
- Binding affinities and spectra of complexes formed by dehydrotetrapyrido[20]annulene and small molecules
- Comparison of spectrophotometric and HPLC methods for determination of lipid peroxidation products in rat brain tissues
- Enantioselective extraction of mandelic acid enantiomers by L-dipentyl tartrate and β-cyclodextrin as binary chiral selectors
- Mechanism of thermal decomposition of cobalt acetate tetrahydrate
- Three-component, one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones catalyzed by bromodimethylsulfonium bromide
