8. A Principle of Developmental Inertia

Kapitel in diesem Buch

1. Frontmatter i
2. Contents v
3. Contributors vii
4. 1. Introduction 1
5. Part One. Historical and Philosophical Foundations
6. 2. A Brief History of the Term and Concept Epigenetics 9
7. 3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution 14
8. Part Two. Approaches to Epigenetics
9. 4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants 43
10. 5. Methylation Mapping in Humans 70
11. 6. Asexuality and Epigenetic Variation 87
12. 7. Epigenesis, Preformation, and the Humpty Dumpty Problem 103
13. 8. A Principle of Developmental Inertia 116
14. Part Three. Epigenetics of Vertebrate Organ Development
15. 9. The Role of Epigenetics in Nervous System Development 137
16. 10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches 164
17. 11. Epigenetic Interactions of the Cardiac Neural Crest 181
18. 12. Epigenetics in Bone and cartilage Development 195
19. 13. Muscle–Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull 221
20. 14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb 238
21. 15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices 256
22. Part Four. Epigenetics in Evolution and Disease
23. 16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis 271
24. 17. Epigenetic Interactions: The Developmental Route to Functional Integration 290
25. 18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback 317
26. 19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution 337
27. 20. Epigenetics: Adaptation or Contingency? 357
28. 21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example 377
29. 22. Epigenetics of Human Disease 398
30. 23. Epigenetics: The Context of Development 424
31. Index 439