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3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution
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James Griesemer
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Chapters in this book
- Frontmatter i
- Contents v
- Contributors vii
- 1. Introduction 1
-
Part One. Historical and Philosophical Foundations
- 2. A Brief History of the Term and Concept Epigenetics 9
- 3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution 14
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Part Two. Approaches to Epigenetics
- 4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants 43
- 5. Methylation Mapping in Humans 70
- 6. Asexuality and Epigenetic Variation 87
- 7. Epigenesis, Preformation, and the Humpty Dumpty Problem 103
- 8. A Principle of Developmental Inertia 116
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Part Three. Epigenetics of Vertebrate Organ Development
- 9. The Role of Epigenetics in Nervous System Development 137
- 10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches 164
- 11. Epigenetic Interactions of the Cardiac Neural Crest 181
- 12. Epigenetics in Bone and cartilage Development 195
- 13. Muscle–Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull 221
- 14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb 238
- 15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices 256
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Part Four. Epigenetics in Evolution and Disease
- 16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis 271
- 17. Epigenetic Interactions: The Developmental Route to Functional Integration 290
- 18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback 317
- 19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution 337
- 20. Epigenetics: Adaptation or Contingency? 357
- 21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example 377
- 22. Epigenetics of Human Disease 398
- 23. Epigenetics: The Context of Development 424
- Index 439
Chapters in this book
- Frontmatter i
- Contents v
- Contributors vii
- 1. Introduction 1
-
Part One. Historical and Philosophical Foundations
- 2. A Brief History of the Term and Concept Epigenetics 9
- 3. Heuristic Reductionism and the Relative significance of Epigenetic Inheritance in evolution 14
-
Part Two. Approaches to Epigenetics
- 4. The Epigenetics of Genomic Imprinting: Core Epigenetic Processes are conserved in Mammals, Insects, and Plants 43
- 5. Methylation Mapping in Humans 70
- 6. Asexuality and Epigenetic Variation 87
- 7. Epigenesis, Preformation, and the Humpty Dumpty Problem 103
- 8. A Principle of Developmental Inertia 116
-
Part Three. Epigenetics of Vertebrate Organ Development
- 9. The Role of Epigenetics in Nervous System Development 137
- 10. Morphogenesis of Pigment Patterns: Experimental and Modeling Approaches 164
- 11. Epigenetic Interactions of the Cardiac Neural Crest 181
- 12. Epigenetics in Bone and cartilage Development 195
- 13. Muscle–Bone Interactions and the Development of skeletal Phenotype: Jaw muscles and the skull 221
- 14. Evolution of the Apical Ectoderm in the Developing Vertebrate Limb 238
- 15. Role of Skeletal Muscle in the Epigenetic Shaping of Organs, Tissues, and Cell Fate Choices 256
-
Part Four. Epigenetics in Evolution and Disease
- 16. Epigenetic Integration, Complexity, and Evolvability of the Head: Rethinking the Functional Matrix Hypothesis 271
- 17. Epigenetic Interactions: The Developmental Route to Functional Integration 290
- 18. Epigenetic Contributions to Adaptive Radiation: Insights from Threespine Stickleback 317
- 19. Learning, Developmental Plasticity, and the Rate of Morphological Evolution 337
- 20. Epigenetics: Adaptation or Contingency? 357
- 21. The Epigenetics of Dysmorphology. Craniosynostosis as an Example 377
- 22. Epigenetics of Human Disease 398
- 23. Epigenetics: The Context of Development 424
- Index 439