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Studies on Hydrogen Bond Formation of Papaverine and Pentazocine
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J. Gangopadhyay
Published/Copyright:
September 25, 2009
Hydrogen bond formation is important in drug-receptor interactions.
Therefore the hydrogen bond formation of the drugs papaverine and pentazocine with alcohols and phenols were studied. The results suggest that hydrogen bonding is more prominent in papaverine than hydrophobic interactions whereas the reverse is the case for pentazocine where hydrophobic interactions overweigh its hydrogen bonding capability.
Published Online: 2009-09-25
Published in Print: 2000-02
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Articles in the same Issue
- A Dielectric Relaxation Study of Lithium Salt Solutions in Dimethylsulfoxide
- Quantitative Determination of Photokinetic Parameters for Reversible Photoisomerizations in Light Scattering Adsorbent-Adsorbates
- Studies on Hydrogen Bond Formation of Papaverine and Pentazocine
- Reaction between 8-Hydroxyquinoline and Salicylic Acid in Solid State and Solution
- Particle Entropies and Entropy Quanta. I. The Ideal Gas
- Dynamical and Quantumchemical Characteristics of Electronic Charge Density Transfer Processes
- Raman Spectroscopic Studies of Scandium(III) Hydration in Aqueous Solution - about the First Hydration Sphere of Sc(III) in Solution
- T,p-Dependence of Self-Diffusion in the Lower N-methylsubstituted Amides
- Time Necessary for Reaching Chemical Equilibrium: First Passage Time Approach
