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New flavonoid C–O–C dimers and other chemical constituents from Garcinia brevipedicellata stem heartwood

  • Bintou Abderamane , Anastasie E. Tih , Raphael T. Ghogomu EMAIL logo , Alain Blond and Bernard Bodo
Published/Copyright: June 25, 2016
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Abstract

The methanol extract of the stem heartwood of Garcinia brevipedicellata has furnished three new flavonoid C–O–C dimers, brevipedicilones A (6), B (8) and C (10), along with five previously reported flavonoid dimers, viz. amentoflavone (1), 4″′-O-methylamentoflavone (2), robustaflavone (3), 4′-O-methyl robustaflavone (4) and tetrahinokiflavone (5). The new structures, which are composed of flavanone–flavanonol or flavanonol–flavanonol sub-units, were established based on spectroscopic analysis including 1D and 2D NMR (1H-1H COSY, HSQC, HMBC, and NOESY) spectroscopy, and by comparing their spectral data with those reported for related compounds.

Acknowledgments

We thank the University of Yaounde for financial support, Mr. Lionel Debost for mass spectra and Mr. Nana Victor of the National Herbarium Yaounde for the collection and the identification of plant material.

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Received: 2015-5-25
Revised: 2015-8-2
Accepted: 2016-5-20
Published Online: 2016-6-25
Published in Print: 2016-7-1

©2016 Walter de Gruyter GmbH, Berlin/Boston

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