A critical review on scale-up strategies of biosurfactant production and its applications

Huria Rizvi; Ashish

doi:10.1515/tsd-2023-2567

Article

A critical review on scale-up strategies of biosurfactant production and its applications

Huria Rizvi
Huria Rizvi is a Ph.D. research scholar in the Department of Bioengineering, Integral University, Lucknow. She received her B.Tech and M.Tech dual degree in Biotechnology. Her area of research is biosurfactant production, bioremediation, scale-up strategies and bioprocess engineering. She has published articles in the area of biosurfactant production and applications.
and Ashish
Dr. Ashish is working as Assistant Professor in the Department of BioEngineering Integral University, Lucknow. He have more than 6 year of teaching/ research experience. He earned his Ph.D degree in Biochemical Engineering from IIT(BHU), Varanasi. His area of research is biochemical engineering, bioremediation, scale-up strategies in bioreactor. He has published many research articles and book chapters in the field of biosurfactant production and applications.

Published/Copyright: May 27, 2024

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From the journal Tenside Surfactants Detergents Volume 61 Issue 4

Abstract

Eco-friendly, biodegradable, microbially produced surfactants, known as biosurfactants, have been intensively studied for their ability as potential substitutes for their synthetic counterparts. Currently, the commercialization of biosurfactants compared to synthetic (chemical) surfactants remains an economic challenge due to high production costs and lower yields. This review details the challenges and better strategies for industrial scale-up of biosurfactant production and downstream processing techniques. An analysis of the use of low cost, renewable substrates, parameter optimization, strain improvement, bioreactor engineering is discussed. The role of various engineering factors that help in scale-up of biosurfactant production such as drag coefficient, Reynolds number, Enrichment ratio, Eӧtvӧs number have also been considered in this review article. The review article demonstrates the potential activity of integrated separation processes and applications of biosurfactants, bringing biosurfactants into mainstream commercialization.

Keywords: biosurfactants; scale-up; hyper producers; downstream processing

Corresponding author: Ashish, Department of Bioengineering, Integral University, Lucknow 226026, India, E-mail: ashish@iul.ac.in

About the authors

Huria Rizvi

Huria Rizvi is a Ph.D. research scholar in the Department of Bioengineering, Integral University, Lucknow. She received her B.Tech and M.Tech dual degree in Biotechnology. Her area of research is biosurfactant production, bioremediation, scale-up strategies and bioprocess engineering. She has published articles in the area of biosurfactant production and applications.

Ashish

Dr. Ashish is working as Assistant Professor in the Department of BioEngineering Integral University, Lucknow. He have more than 6 year of teaching/ research experience. He earned his Ph.D degree in Biochemical Engineering from IIT(BHU), Varanasi. His area of research is biochemical engineering, bioremediation, scale-up strategies in bioreactor. He has published many research articles and book chapters in the field of biosurfactant production and applications.

Acknowledgments

The authors wish to thank the Department of Bioengineering, Integral University, Lucknow, India for providing laboratory and technical support. MCN-IU/R&D/2022-MCN0001546.

Research ethics: Not applicable.
Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission. Hurua Rizvi wrote the manuscript, Dr. Ashish gave the idea of whole review paper and edited the manuscript.
Competing interests: The authors state no conflict of interest.
Research funding: None declared.
Data availability: Not applicable.

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Received: 2023-11-04

Accepted: 2024-02-06

Published Online: 2024-05-27

Published in Print: 2024-07-26

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https://doi.org/10.1515/tsd-2023-2567

Keywords for this article

biosurfactants; scale-up; hyper producers; downstream processing