Numerical assessment of coaptation for auto-pericardium based aortic valve cusps
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Victoria Yu. Salamatova
, Alexey A. Liogky
Abstract
Aortic valve disease accounts for 45% of deaths from heart valve diseases.% \cite{Coffey2015}. An appealing approach to treat aortic valve disease is surgical replacement of the valve leaflets based on chemically treated autologous pericardium. This procedure is attractive due to its low cost and high effectiveness. We aim to develop a computational technology for patient-specific assessment of reconstructed aortic valve function that can be used by surgeons at the preoperative stage. The framework includes automatic computer tomography image segmentation, mesh generation, simulation of valve leaflet deformation. The final decision will be based on uncertainty analysis and leaflet shape optimization. This paper gives a proof of concept of our methodology: simulation methods are presented and studied numerically.
Funding: The work was supported by the RFBR grants 18-00-01524, 18-31-20048, 17-01-00886.
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© 2019 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Computer modelling of initial platelet adhesion during microvascular thrombosis
- Spatially resolved modelling of immune responses following a multiscale approach: from computational implementation to quantitative predictions
- Pump eflciency of lymphatic vessels: numeric estimation
- Stability indicatrices of nonnegative matrices and some of their applications in problems of biology and epidemiology
- Numerical assessment of coaptation for auto-pericardium based aortic valve cusps
- Lumped parameter heart model with valve dynamics
Articles in the same Issue
- Frontmatter
- Computer modelling of initial platelet adhesion during microvascular thrombosis
- Spatially resolved modelling of immune responses following a multiscale approach: from computational implementation to quantitative predictions
- Pump eflciency of lymphatic vessels: numeric estimation
- Stability indicatrices of nonnegative matrices and some of their applications in problems of biology and epidemiology
- Numerical assessment of coaptation for auto-pericardium based aortic valve cusps
- Lumped parameter heart model with valve dynamics