Physicochemical and free radical scavenging activity of Adansonia digitata seed oil
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Emmanuel Mshelia Halilu
and
Nafisa Kudu Muhammad
Abstract
Adansonia digitata is used in folk medicine as antipyretic, analgesic and as an antioxidant. The aim of the research was to study the physicochemical, antioxidant and acute toxicity profiles of the oil extracted from the seed nuts. Standard methods were used to ascertain the physicochemical parameters, antioxidant properties and the oral acute toxicity. The moisture content (MC), total ash (TA), acid insoluble ash (AIA), alcohol soluble extractive (ASE) and the water-soluble extractive (WSE) were: 4 %, 4 %, 0.33 %, 22 % and 20.67 % respectively. The oil yielded 15.29 %. The GC-MS revealed some fatty acids/esters. The oil was soluble in varieties organic solvents including petroleum ether, benzene, chloroform and others. Steroids were detected in the oil through qualitative phytochemical screening. The saponification value (SV) of 30.86 mgKOH/g, acid value (AV) of 140.25 mgKOH/g, Ester value (EV) of 109.39 mgKOH/g, iodine value (IV) of 104.05 gI2/100 g and specific gravity (SG) of 0.92 were obtained. The oil was safe up to a dose of 5000 mg/kg per body weight via the oral route at one dose level. The DPPH free radical scavenging activity of the oil showed the highest inhibition (92.3 %) at 3.30 mg/mL and the least inhibition of 86.6 % at 0.12 mg/mL. Therefore, this research has revealed that Adansonia digitata oil contain phytochemicals with free radical scavenging properties and the oil is not toxic.
Acknowledgements
The authors expressed their appreciation to Mr. Aliyu and Mr. Abdullahi of the department of pharmacognosy and ethnomedicine, and pharmacology and toxicology, respectively, for their technical assistance.
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Author contribution: The authors contributed equally to the research.
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Research funding: None declared.
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Conflict of interest statement: The authors declared no conflicts of interest regarding this article.
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Articles in the same Issue
- Frontmatter
- Reviews
- Circular plastics technologies: pyrolysis of plastics to fuels and chemicals
- Morphological, water barrier and biodegradable properties of sugar palm nanocellulose/starch biopolymer composites incorporated with cinnamon essential oils
- Plant-based biopolymers for wastewater pollutants mitigation
- Oat thermoplastic starch nanocomposite films reinforced with nanocellulose
- Miniaturization and microfluidic devices: an overview of basic concepts, fabrication techniques, and applications
- Pea thermoplastic starch nanocomposite films reinforced with nanocellulose
- Biopolymer based membrane technology for environmental applications
- Characterization of crude saponins from stem bark extract of Parinari curatellifolia and evaluation of its antioxidant and antibacterial activities
- Random and block architectures of N-arylitaconimide monomers with methyl methacrylate
- Physicochemical and free radical scavenging activity of Adansonia digitata seed oil
