Abstract
Both cinnolines and phthalazines are heterocyclic compounds which have a wide range of biological activities and pharmacological profiles. This work represents the recent advances in the green synthesis of cinnolines and phthalazines as 1,2 and 2,3-diazanaphalenes were cited. The docking studies and mode of action for key scaffolds were also reported.
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Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
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Research funding: None declared.
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Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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© 2022 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Reviews
- Recent endeavors in microbial remediation of micro- and nanoplastics
- Metal nanoparticles and its application on phenolic and heavy metal pollutants
- The story of nitrogen
- Recent development of imidazole derivatives as potential anticancer agents
- Indole based prostate cancer agents
- Lawsone (2-hydroxy-1,4-naphthaquinone) derived anticancer agents
- Small modular nuclear reactors are mostly bad policy
- A holistic environmental investigation of complementary energy in Alberta
- Green synthesis of various saturated S-heterocyclic scaffolds: an update
- Recent advances of heterocycle based anticancer hybrids
- Molecular docking and MD: mimicking the real biological process
- Synthesis of quinazolinone and quinazoline derivatives using green chemistry approach
- Nuclear fusion: the promise of endless energy
- Finance for Green Chemistry through Currency Mix
- Synthesis of bioactive scaffolds catalyzed by agro-waste-based solvent medium
- Recent developments in the green synthesis of biologically relevant cinnolines and phthalazines
- Detection of Rapid Eye Movement Behaviour Sleep Disorder using Time and Frequency Analysis of EEG Signal Applied on C4-A1 Channels
- Recent developments in C–C bond formation catalyzed by solid supported palladium: a greener perspective
- Visible-light-mediated metal-free C–Si bond formation reactions
- An overview of quinoxaline synthesis by green methods: recent reports
- Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs
- Synthesis of bioactive natural products and their analogs at room temperature – an update
- One-pot multi-component synthesis of diverse bioactive heterocyclic scaffolds involving 6-aminouracil or its N-methyl derivatives as a versatile reagent
- Synthesis of new horizons in benzothiazole scaffold and used in anticancer drug development
- Triazine based chemical entities for anticancer activity
- Modification of kaolinite/muscovite clay for the removal of Pb(II) ions from aqueous media
- In silico design of ACE2 mutants for competitive binding of SARS-CoV-2 receptor binding domain with hACE2
- Computational study of Cu n AgAu (n = 1–4) clusters invoking DFT based descriptors
- Development of an online assessment system to evaluate knowledge on chemical safety and security
- Developing a questionnaire for diabetes mellitus type 2 risk effects and precondition factors – multivariate statistical paths
- Antioxidant and antibacterial activities of two xanthones derivatives isolated from the leaves extract of Anthocleista schweinfurthii Gilg (Loganiaceae)
- The stability increase of α-amylase enzyme from Aspergillus fumigatus using dimethyladipimidate
- Sustainability of ameliorative potentials of urea spiked poultry manure biochar types in simulated sodic soils
- Cytotoxicity test and antibacterial assay on the compound produced by the isolation and modification of artonin E from Artocarpus kemando Miq.
- Effects of alum, soda ash, and carbon dioxide on 40–50 year old concrete wastewater tanks
Articles in the same Issue
- Frontmatter
- Reviews
- Recent endeavors in microbial remediation of micro- and nanoplastics
- Metal nanoparticles and its application on phenolic and heavy metal pollutants
- The story of nitrogen
- Recent development of imidazole derivatives as potential anticancer agents
- Indole based prostate cancer agents
- Lawsone (2-hydroxy-1,4-naphthaquinone) derived anticancer agents
- Small modular nuclear reactors are mostly bad policy
- A holistic environmental investigation of complementary energy in Alberta
- Green synthesis of various saturated S-heterocyclic scaffolds: an update
- Recent advances of heterocycle based anticancer hybrids
- Molecular docking and MD: mimicking the real biological process
- Synthesis of quinazolinone and quinazoline derivatives using green chemistry approach
- Nuclear fusion: the promise of endless energy
- Finance for Green Chemistry through Currency Mix
- Synthesis of bioactive scaffolds catalyzed by agro-waste-based solvent medium
- Recent developments in the green synthesis of biologically relevant cinnolines and phthalazines
- Detection of Rapid Eye Movement Behaviour Sleep Disorder using Time and Frequency Analysis of EEG Signal Applied on C4-A1 Channels
- Recent developments in C–C bond formation catalyzed by solid supported palladium: a greener perspective
- Visible-light-mediated metal-free C–Si bond formation reactions
- An overview of quinoxaline synthesis by green methods: recent reports
- Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs
- Synthesis of bioactive natural products and their analogs at room temperature – an update
- One-pot multi-component synthesis of diverse bioactive heterocyclic scaffolds involving 6-aminouracil or its N-methyl derivatives as a versatile reagent
- Synthesis of new horizons in benzothiazole scaffold and used in anticancer drug development
- Triazine based chemical entities for anticancer activity
- Modification of kaolinite/muscovite clay for the removal of Pb(II) ions from aqueous media
- In silico design of ACE2 mutants for competitive binding of SARS-CoV-2 receptor binding domain with hACE2
- Computational study of Cu n AgAu (n = 1–4) clusters invoking DFT based descriptors
- Development of an online assessment system to evaluate knowledge on chemical safety and security
- Developing a questionnaire for diabetes mellitus type 2 risk effects and precondition factors – multivariate statistical paths
- Antioxidant and antibacterial activities of two xanthones derivatives isolated from the leaves extract of Anthocleista schweinfurthii Gilg (Loganiaceae)
- The stability increase of α-amylase enzyme from Aspergillus fumigatus using dimethyladipimidate
- Sustainability of ameliorative potentials of urea spiked poultry manure biochar types in simulated sodic soils
- Cytotoxicity test and antibacterial assay on the compound produced by the isolation and modification of artonin E from Artocarpus kemando Miq.
- Effects of alum, soda ash, and carbon dioxide on 40–50 year old concrete wastewater tanks