Startseite Fabrication and characterization of three-dimensional polycaprolactone/sodium alginate and egg whites and eggshells hybrid scaffold in bone tissue engineering
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Fabrication and characterization of three-dimensional polycaprolactone/sodium alginate and egg whites and eggshells hybrid scaffold in bone tissue engineering

  • Hessam Rezaei ORCID logo , Mostafa Shahrezaee EMAIL logo , Marziyeh Jalali Monfared , Mona Nikjou , Mohammad Hossein Shahrezaee und Mojdeh Mohseni
Veröffentlicht/Copyright: 11. November 2022
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Abstract

The aim of this study was to fabricate three-dimensional bone scaffolds using polycaprolactone and egg shell powder. The scaffolds were coated with sodium alginate/egg white. SEM was used to investigate egg shell particles on the surface of each string of scaffolds. The presence of calcium carbonate in the scaffold structure was confirmed by microstructural analyses employing XRD. Egg shell-related functional groups were discovered using FTIR investigations. Bone cells were used to conduct biocompatibility tests on scaffolds (MG-63). Finally, scaffolds with the highest proportion of egg whites and eggshells have the best cell survival rate. It may be concluded that the PCL/7% Esh/15% Ew scaffold is a good option for application in bone tissue engineering.


Corresponding author: Mostafa Shahrezaee, Department of Orthopedic Surgery, School of Medicine, Aja University of Medical Sciences, Tehran 1411718541, Iran, E-mail:

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2022-06-18
Accepted: 2022-08-14
Published Online: 2022-11-11
Published in Print: 2023-01-27

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