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Chemical substitution in processes for inherently safer design: pros and cons

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Published/Copyright: April 25, 2022
Pure and Applied Chemistry
From the journal Pure and Applied Chemistry Volume 94 Issue 7

Abstract

The aim of chemical substitution is to replace hazardous chemicals with a less hazardous alternative in a certain product or process to make it safer for human health and the environment. While a lot has been done by researchers, industries and regulatory bodies on chemical substitution for safer products, very little has been reported in the field of safer processes. On the other hand, chemical substitution is one of the core principles of inherently safer design, a concept frequently used in the chemical industry for the prevention of major accidents. This work presents an analysis of implementing chemical substitution methodology for safer processes through inherently safer design. Chemical industries, nowadays, are frequently asked to phase out hazardous chemicals from their processes. This paper provides an insight into the issues and practicability of chemical substitution in processes with the help of case studies and a review of the existing frameworks of inherently safer design.

Keywords: alternative assessment; chemical substitution; chemistry and its applications; hazardous chemicals; inherently safer design; sustainability; VCCA-2021
Corresponding author: Sultana R. Syeda, Department of Chemical Engineering, Bangladesh University of Engineering and Technology, Dhaka 1000, Bangladesh, e-mail:
Article note: A collection of invited papers based on presentations at the Virtual Conference on Chemistry and its Applications (VCCA-2021) held on-line, 9–13 August 2021.

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Published Online: 2022-04-25
Published in Print: 2022-07-26

© 2022 IUPAC & De Gruyter. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. For more information, please visit: http://creativecommons.org/licenses/by-nc-nd/4.0/

Articles in the same Issue

  1. Frontmatter
  2. In this issue
  3. Editorial
  4. The virtual conference on chemistry and its applications, VCCA-2021, 9–13 August 2021
  5. Conference papers
  6. Hexabenzocoronene functionalized with antiaromatic S- and Se-core-modified porphyrins (isophlorins): comparison with the dyad with regular porphyrin
  7. Bonding analysis of the C2 precursor Me3E–C2–I(Ph)FBF3 (E = C, Si, Ge)
  8. Supporting the fight against the proliferation of chemical weapons through cheminformatics
  9. Disinfecting activity of some diphenyltin(IV) benzoate derivative compounds
  10. HCV genotype-specific drug discovery through structure-based virtual screening
  11. ExcelAutomat 1.4: generation of supporting information
  12. Use of Circular Dichroism in the characterization of the fusion protein SARS-CoV-2 S protein (RBD)-hFc
  13. Experimental determination of activation rate constant and equilibrium constant for bromo substituted succinimide initiators for an atom transfer radical polymerization process
  14. Degradation of o-, m-, p-cresol isomers using ozone in the presence of V2O5-supported Mn, Fe, and Ni catalysts
  15. The beginnings of chemistry: from ancient times until 1661
  16. Chemical substitution in processes for inherently safer design: pros and cons
  17. Experimental and theoretical study of the dye-sensitized solar cells using Hibiscus sabdariffa plant pigment coupled with polyaniline/graphite counter electrode
https://doi.org/10.1515/pac-2021-1201
Keywords for this article
alternative assessment; chemical substitution; chemistry and its applications; hazardous chemicals; inherently safer design; sustainability; VCCA-2021

Articles in the same Issue

  1. Frontmatter
  2. In this issue
  3. Editorial
  4. The virtual conference on chemistry and its applications, VCCA-2021, 9–13 August 2021
  5. Conference papers
  6. Hexabenzocoronene functionalized with antiaromatic S- and Se-core-modified porphyrins (isophlorins): comparison with the dyad with regular porphyrin
  7. Bonding analysis of the C2 precursor Me3E–C2–I(Ph)FBF3 (E = C, Si, Ge)
  8. Supporting the fight against the proliferation of chemical weapons through cheminformatics
  9. Disinfecting activity of some diphenyltin(IV) benzoate derivative compounds
  10. HCV genotype-specific drug discovery through structure-based virtual screening
  11. ExcelAutomat 1.4: generation of supporting information
  12. Use of Circular Dichroism in the characterization of the fusion protein SARS-CoV-2 S protein (RBD)-hFc
  13. Experimental determination of activation rate constant and equilibrium constant for bromo substituted succinimide initiators for an atom transfer radical polymerization process
  14. Degradation of o-, m-, p-cresol isomers using ozone in the presence of V2O5-supported Mn, Fe, and Ni catalysts
  15. The beginnings of chemistry: from ancient times until 1661
  16. Chemical substitution in processes for inherently safer design: pros and cons
  17. Experimental and theoretical study of the dye-sensitized solar cells using Hibiscus sabdariffa plant pigment coupled with polyaniline/graphite counter electrode
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