Time interval to delivery in asymptomatic twin pregnancies with a short cervix at 23–28 weeks’ gestation
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Moti Gulersen
,
Matthew J. Blitz
,
Erez Lenchner
Abstract
Objectives
To evaluate the risk and timing of spontaneous preterm birth (PTB) in asymptomatic twin pregnancies with a short cervical length (CL≤25 mm) at 23–28 weeks of gestation.
Methods
Multicenter retrospective cohort study of asymptomatic twin pregnancies with a short CL between 23 and 28 weeks’ gestation within a university health system from 1/2012 to 12/2019. Cases were divided into 4 groups based on CL measurement (≤10 mm, 11–15 mm, 16–20 mm, and 21–25 mm). The primary outcome was time interval from presentation to delivery. Secondary outcomes included delivery within one and two weeks of presentation, and delivery prior to 32, 34, and 37 weeks, respectively.
Results
104 patients were included. The time interval from presentation to delivery was significantly different among the four groups (p<0.001), with the CL≤10 mm group having the shortest time interval to delivery. Regardless of the CL measurement, spontaneous PTB within one and two weeks was extremely uncommon and occurred in only one patient within the study cohort (1/104, 1.0%). The risk of spontaneous PTB was highest in the shortest CL group (CL ≤ 10 mm; 53.8% PTB<32 weeks, 61.5% PTB<34 weeks, 92.3% PTB<37 weeks).
Conclusions
Asymptomatic twin pregnancies with a CL ≤ 10 mm had the shortest time interval to delivery and thus represent a specifically high risk group for sPTB. Although all patients were at high risk of sPTB, only one delivered within 1 or 2 weeks of presentation.
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Research funding: None declared.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: Not applicable.
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Ethical approval: The local Institutional Review Board deemed the study exempt from review.
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© 2022 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Reviews
- Placenta Accreta Spectrum Part I: anesthesia considerations based on an extended review of the literature
- Placenta Accreta Spectrum Part II: hemostatic considerations based on an extended review of the literature
- Corner of Academy
- The impact of lateral placenta on preeclampsia and small for gestational age neonates: a systematic review and meta-analysis
- Original Articles – Obstetrics
- Fetal intelligent navigation echocardiography (FINE) has superior performance compared to manual navigation of the fetal heart by non-expert sonologists
- Evaluation of fetal middle adrenal artery Doppler and fetal adrenal gland size in pregnancies with fetal growth restriction: a case-control study
- First trimester low maternal serum pregnancy associated plasma protein-A (PAPP-A) as a screening method for adverse pregnancy outcomes
- Time interval to delivery in asymptomatic twin pregnancies with a short cervix at 23–28 weeks’ gestation
- Hepatic arterial buffer response in monochorionic diamniotic pregnancies with twin-to-twin transfusion syndrome
- Healthcare of pregnant women with diabetes during the COVID-19 pandemic: a Southern Brazilian cross-sectional panel data
- Attitudes toward COVID-19 vaccination of pregnant and lactating women in Hungary
- Maternal vitamin D levels correlate with fetal weight and bone metabolism during pregnancy: a materno-neonatal analysis of bone metabolism parameters
- Removal of pregnancy categories and likelihood of prescribing: a randomized trial
- Prenatal prediction of Shone’s complex. The role of the degree of ventricular disproportion and speckle-tracking analysis
- Original Article – Fetus
- The effect of middle cerebral artery peak systolic velocity on prognosis in early and late-onset fetal growth restriction
- Original Articles – Neonates
- Assessment of salivary cortisol concentrations for procedural pain monitoring in newborns
- Impact on neonatal morbidities after a change in policy to administer antenatal corticosteroids to mothers at risk for late preterm delivery
- The Apgar score in clinical research: for what, how and by whom it is used
- Short Communication
- Visitor restriction during the COVID-19 pandemic did not impact rates of Staphylococcus aureus colonization in the NICU patients
- Letter to the Editor
- Knowledge and attitudes of pregnant women on maternal immunization against COVID-19: correspondence
Articles in the same Issue
- Frontmatter
- Reviews
- Placenta Accreta Spectrum Part I: anesthesia considerations based on an extended review of the literature
- Placenta Accreta Spectrum Part II: hemostatic considerations based on an extended review of the literature
- Corner of Academy
- The impact of lateral placenta on preeclampsia and small for gestational age neonates: a systematic review and meta-analysis
- Original Articles – Obstetrics
- Fetal intelligent navigation echocardiography (FINE) has superior performance compared to manual navigation of the fetal heart by non-expert sonologists
- Evaluation of fetal middle adrenal artery Doppler and fetal adrenal gland size in pregnancies with fetal growth restriction: a case-control study
- First trimester low maternal serum pregnancy associated plasma protein-A (PAPP-A) as a screening method for adverse pregnancy outcomes
- Time interval to delivery in asymptomatic twin pregnancies with a short cervix at 23–28 weeks’ gestation
- Hepatic arterial buffer response in monochorionic diamniotic pregnancies with twin-to-twin transfusion syndrome
- Healthcare of pregnant women with diabetes during the COVID-19 pandemic: a Southern Brazilian cross-sectional panel data
- Attitudes toward COVID-19 vaccination of pregnant and lactating women in Hungary
- Maternal vitamin D levels correlate with fetal weight and bone metabolism during pregnancy: a materno-neonatal analysis of bone metabolism parameters
- Removal of pregnancy categories and likelihood of prescribing: a randomized trial
- Prenatal prediction of Shone’s complex. The role of the degree of ventricular disproportion and speckle-tracking analysis
- Original Article – Fetus
- The effect of middle cerebral artery peak systolic velocity on prognosis in early and late-onset fetal growth restriction
- Original Articles – Neonates
- Assessment of salivary cortisol concentrations for procedural pain monitoring in newborns
- Impact on neonatal morbidities after a change in policy to administer antenatal corticosteroids to mothers at risk for late preterm delivery
- The Apgar score in clinical research: for what, how and by whom it is used
- Short Communication
- Visitor restriction during the COVID-19 pandemic did not impact rates of Staphylococcus aureus colonization in the NICU patients
- Letter to the Editor
- Knowledge and attitudes of pregnant women on maternal immunization against COVID-19: correspondence
