Clinical characteristics and outcome of twin pregnancies complicated by single intrauterine death
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Qiong Luo
Abstract:
Aim:
To investigate the clinical characteristics and outcome of twin pregnancies complicated by single intrauterine death and how to improve the outcomes of surviving twins. Three thousand three hundred and eighty-four women who delivered twin pregnancies at Women’s Hospital, Zhejiang University, School of Medicine were included. Clinical and demographic data on gestational age, etiology, morbidity and mortality for mothers and fetuses were collected.
Results:
The median gestational age for detecting a single intrauterine death in twin pregnancy was 29 weeks and the average gestational age of pregnancy termination was 32 weeks. At least one complication occurred in 93 of 134 mothers (69.4%). The leading causes of a single intrauterine death were umbilical cord abnormality (21.6%), congenital anomalies (17.9%), twin-twin transfusion syndrome (TTTS) (8.2%) and velamentous placenta (7.4%). Of the 134 cases, in 115 cases the remaining twin survived. The birth weight of the surviving twin was significantly higher in pregnancies that continued for more than 1 week after single intrauterine death compared to that ended within 1 week after intrauterine death.
Conclusions:
Extension of gestation for the surviving twin fetus as long as possible in ensuring the health of the surviving twin and mother, will improve the prognosis of surviving twin after a single intrauterine death.
Author’s statement
Conflict of interest: Authors state no conflict of interest.
Material and methods: Informed consent: Informed consent has been obtained from all individuals included in this study.
Ethical approval: The research related to human subject use has complied with all the relevant national regulations, and institutional policies, and is in accordance with the tenets of the Helsinki Declaration, and has been approved by the authors’ institutional review board or equivalent committee.
Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: National Natural Science Foundation of China (No. 81571447), and Major Science and Technology Projects in Zhejiang Province (2012C13024-2).
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©2018 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
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- Original articles – Fetus
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- Original articles – Newborn
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- Letter to the Editor
- Exact days of gestation necessary for infants at borderline viability: reply to Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23weeks’ gestation. P. Šimják, J. Smíšek, M. Koucký, T. Lamberská, R. Plavka and Z. Hájek. J Perinat Med 2017
Artikel in diesem Heft
- Frontmatter
- Review article
- The assessment of labor: a brief history
- Original articles – Obstetrics
- The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates
- Uterine artery Doppler pulsatility index at 11–38 weeks in ICSI pregnancies with egg donation
- Violence before pregnancy and the risk of violence during pregnancy
- Cancer during pregnancy – clinical characteristics, treatment outcomes and prognosis for mothers and infants
- The effect of attending a prenatal childbirth preparedness course on labor duration and outcomes
- Serum fibrinogen levels could be an index of successful use of balloon tamponade in postpartum hemorrhage
- Impact factors on cervical dilation rates in the first stage of labor
- Feasibility and acceptability of text messaging to support antenatal healthcare in Iraqi pregnant women: a pilot study
- Clinical characteristics and outcome of twin pregnancies complicated by single intrauterine death
- Utility of routine urine CMV PCR and total serum IgM testing of small for gestational age infants: a single center review
- The association between pre-pregnancy obesity and screening results of depression for all trimesters of pregnancy, postpartum and 1 year after birth: a cohort study
- Original articles – Fetus
- Causes of intrauterine fetal death are changing in recent years
- Original articles – Newborn
- Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks’ gestation
- Letter to the Editor
- Exact days of gestation necessary for infants at borderline viability: reply to Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23weeks’ gestation. P. Šimják, J. Smíšek, M. Koucký, T. Lamberská, R. Plavka and Z. Hájek. J Perinat Med 2017
