Absence of antibodies against Bordetella pertussis in pregnant women and newborns in the state of Nuevo Leon
-
Jesús Zacarías Villarreal-Pérez
,
Irasema Rodríguez-Rodríguez
Abstract
Aims: To assess placental transfer of antibodies to the child at birth and at 2 months of age.
Materials and methods: For the quantification of anti-PT IgG antibodies, we used an indirect enzyme-linked immunosorbent assay standardized by The National Institute of Epidemiologic Diagnosis and Reference (InDRE). Samples were considered negative from 0 to 48 IU/mL, indeterminate from 49 to 93 IU/mL and positive at ≥94 IU/mL. We performed a cross-sectional assessment of anti-PT IgG antibody levels in the mother, umbilical cord, and child.
Results: There was a higher concentration of IgG anti-TP in the umbilical cord (4.3%) and in the mother (1.4%), but a total absence was observed in the child (0%).
Conclusion: The vulnerability of children to Bordetella pertussis shows the need to implement effective immunization strategies, whether actively, in the child, or passively through the mother, adolescents, and adults who are in contact with the child.
Acknowledgements
We thank the obstetrics and gynecology as well as nursing staff of the High Specialty Maternity-Child Hospital Laboratory. We also wish to thank the staff of the State Public Health Laboratory of the SSNL. Finally, we appreciate the support of Jose Pulido-Mata, who reviewed and proofread the manuscript, and Sergio Lozano-Rodriguez, M.D., who translated and edited the manuscript. This research was funded with support from the Joint Fund (FOMIX), with contributions from the Government of the State of Nuevo Leon and the National Council for Science and Technology (CONACYT).
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©2014 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Editorial
- The CROWN Initiative: journal editors invite researchers to develop core outcomes in women’s health
- Academy’s Corner
- Invasive or non-invasive prenatal genetic diagnosis?
- Original articles - Obstetrics
- Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy
- Analysis of measurement process of placental volume in early pregnancy: an interobserver reliability study
- Acute pancreatitis in pregnancy: a comparison of associated conditions, treatments and complications
- Cesarean section and placental disorders in subsequent pregnancies – a meta-analysis
- Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births
- Prediction of preeclampsia by placental protein 13 and background risk factors and its prevention by aspirin
- Maternal and neonatal outcome of labour induction at term comparing two regimens of misoprostol
- Comparison of placental alpha microglobulin-1 in vaginal fluid with intra-amniotic injection of indigo carmine for the diagnosis of rupture of membranes
- Clinical differences between early- and late-onset severe preeclampsia and analysis of predictors for perinatal outcome
- Maternal serum placental growth factor and fetal SGA in pregnancy complicated by type 1 diabetes mellitus
- Original article – Fetus
- Imaging of fetal thymus in pregnant women with rheumatic diseases
- Original articles – Newborn
- Milk demystified by chemistry
- Absence of antibodies against Bordetella pertussis in pregnant women and newborns in the state of Nuevo Leon
- Mortality among sons of female dental personnel – a national cohort study
- IAPM Statements 2005–2012
- DECLARATIONS of the “International Academy of Perinatal Medicine” (IAPM)
- Congress Calendar
- Congress Calendar
Artikel in diesem Heft
- Frontmatter
- Editorial
- The CROWN Initiative: journal editors invite researchers to develop core outcomes in women’s health
- Academy’s Corner
- Invasive or non-invasive prenatal genetic diagnosis?
- Original articles - Obstetrics
- Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy
- Analysis of measurement process of placental volume in early pregnancy: an interobserver reliability study
- Acute pancreatitis in pregnancy: a comparison of associated conditions, treatments and complications
- Cesarean section and placental disorders in subsequent pregnancies – a meta-analysis
- Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births
- Prediction of preeclampsia by placental protein 13 and background risk factors and its prevention by aspirin
- Maternal and neonatal outcome of labour induction at term comparing two regimens of misoprostol
- Comparison of placental alpha microglobulin-1 in vaginal fluid with intra-amniotic injection of indigo carmine for the diagnosis of rupture of membranes
- Clinical differences between early- and late-onset severe preeclampsia and analysis of predictors for perinatal outcome
- Maternal serum placental growth factor and fetal SGA in pregnancy complicated by type 1 diabetes mellitus
- Original article – Fetus
- Imaging of fetal thymus in pregnant women with rheumatic diseases
- Original articles – Newborn
- Milk demystified by chemistry
- Absence of antibodies against Bordetella pertussis in pregnant women and newborns in the state of Nuevo Leon
- Mortality among sons of female dental personnel – a national cohort study
- IAPM Statements 2005–2012
- DECLARATIONS of the “International Academy of Perinatal Medicine” (IAPM)
- Congress Calendar
- Congress Calendar
