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Maternal and fetal adropin levels in gestational diabetes mellitus

  • Ebru Celik EMAIL logo , Ercan Yilmaz , Onder Celik , Mustafa Ulas , Ilgin Turkcuoglu , Abdullah Karaer , Yavuz Simsek , Yagmur Minareci and Suleyman Aydin
Published/Copyright: January 9, 2013

Abstract

Aim: To evaluate maternal and cord blood serum adropin concentrations in pregnant women with gestational diabetes mellitus (GDM).

Study design: Twenty pregnant women with GDM and 20 gestational age-matched healthy pregnant women participated in the study. Maternal serum and cord blood adropin levels were assessed using an enzyme immunosorbent assay, at the time of birth. The relation of maternal serum and cord blood adropin levels with metabolic parameters were also assessed.

Results: The mean maternal and cord serum adropin in the GDM group were significantly lower than those of the control women (P=0.01 and P<0.001, respectively). Maternal serum adropin levels did not correlate with either fetal serum adropin levels or maternal metabolic values.

Conclusion: The data suggest that low adropin levels may contribute to the underlying pathogenesis of GDM.


Corresponding author: Ebru Celik, MD, Department of Obstetrics and Gynecology, TurgutOzal Medical Center, Inonu University School of Medicine, 44315, Malatya, Turkey, Tel.: +90 532 603 5151, Fax: +90 422 3410660

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2012-9-19
Accepted: 2012-12-3
Published Online: 2013-01-09
Published in Print: 2013-07-01

©2013 by Walter de Gruyter Berlin Boston

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