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Management of gestational hypertension – the impact of HYPITATa

  • Jaimey M. Pauli EMAIL logo , Julianne R. Lauring , Christy M. Stetter , John T. Repke , John J. Botti , Serdar H. Ural and Anthony Ambrose
Published/Copyright: February 11, 2013

Abstract

Aims: The objective of this study was to examine the impact of one trial (the HYPITAT trial) on management of gestational hypertension.

Study design: This is a retrospective cohort study of 5077 patients delivered at our institution from 7/1/2008 to 6/15/2011. “Pre-HYPITAT” was defined as 7/1/2008–9/30/2009 and “Post-HYPITAT” as 10/1/2009–6/15/2011. The primary outcome is the rate of delivery intervention for gestational hypertension. Secondary maternal and neonatal outcomes were analyzed in patients with gestational hypertension only. Statistical analyses included the χ2-test, Fisher’s exact test, and the two-sample t-test.

Results: The rate of delivery intervention Pre-HYPITAT was 1.9%, compared to 4% Post-HYPITAT (P<0.001). There was no significant change in secondary outcomes.

Conclusion: There was a statistically significant increase in delivery intervention for gestational hypertension at our institution after the publication of the HYPITAT trial. There was no significant change in immediate maternal or neonatal outcomes for patients with gestational hypertension.


Corresponding author: Jaimey M. Pauli, MD, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Penn State University College of Medicine, The Milton S. Hershey Medical Center, 500 University Drive, H103 Hershey, PA 17033, USA, Tel.: +1 717 5318142x5, Fax: +1 717 5310117

  1. a

    Poster presented at The Society for Maternal-Fetal Medicine 32nd Annual Meeting, Dallas, TX, USA, February 6–12, 2012.

References

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2012-8-2
Accepted: 2013-1-4
Published Online: 2013-02-11
Published in Print: 2013-07-01

©2013 by Walter de Gruyter Berlin Boston

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