Polymorphisms in the activin A receptor type 2A gene affect the onset time and severity of preeclampsia in the Turkish population

References

[1] Arngrimsson R, Bjornsson S, Geirsson RT, Bjornsson H, Walker JJ, Snaedal G. Genetic and familial predisposition to eclampsia and pre-eclampsia in a defined population. Br J Obstet Gynaecol. 1990;97:762–9.10.1111/j.1471-0528.1990.tb02569.xSearch in Google Scholar PubMed

[2] Arngrimsson R, Sigurard ttir S, Frigge ML, Bjarnad ttir RI, Jonsson T, Stefansson H, et al. A genome-wide scan reveals a maternal susceptibility locus for pre-eclampsia on chromosome 2p13. Hum Mol Genet. 1999;8:1799–805.10.1093/hmg/8.9.1799Search in Google Scholar PubMed

[3] Caniggia I, Lye SJ, Cross JC. Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology. 1997;138:3976–86.10.1210/endo.138.9.5403Search in Google Scholar PubMed

[4] Cocolakis E, Lemay S, Ali S, Lebrun JJ. The p38MAPK pathway is required for cell growth inhibition of human breast cancer cells in response to activin. J Biol Chem. 2001;276:18430–6.10.1074/jbc.M010768200Search in Google Scholar PubMed

[5] Davison JM, Homuth V, Jeyabalan A, Conrad KP, Karumanchi SA, Quaggin S, et al. New aspects in the pathophysiology of preeclampsia. J Am Soc Nephrol. 2004;15:2440–8.10.1097/01.ASN.0000135975.90889.60Search in Google Scholar PubMed

[6] Duley L. Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean. Br J Obstet Gynaecol. 1992;99:547–53.10.1111/j.1471-0528.1992.tb13818.xSearch in Google Scholar PubMed

[7] Fitzpatrick E, Göring HH, Liu H, Borg A, Forrest S, Cooper DW, et al. Fine mapping and SNP analysis of positional candidates at the pre-eclampsia susceptibility locus (PREG1) on chromosome 2. Hum Biol. 2004;76:849–62.10.1353/hub.2005.0017Search in Google Scholar PubMed

[8] Fitzpatrick E, Johnson MP, Dyer TD, Forrest S, Elliott K, Blangero J, et al. Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia. Mol Hum Reprod. 2009;15: 195–204.10.1093/molehr/gap001Search in Google Scholar PubMed PubMed Central

[9] Harrison GA, Humphrey KE, Jones N, Badenhop R, Guo G, Elakis G, et al. A genome-wide linkage study of preeclampsia/eclampsia reveals evidence for a candidate region on 4q. Am J Hum Genet. 1997;60:1158–67.Search in Google Scholar

[10] Hedger MP, Winnall WR, Phillips DJ, de Kretser DM. The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm. 2011;85:255–97.10.1016/B978-0-12-385961-7.00013-5Search in Google Scholar PubMed

[11] Laivuori H, Lahermo P, Ollikainen V, Widen E, Haiva-Mallinen L, Sundström H, et al. Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families. Am J Hum Genet. 2003;72:168–77.10.1086/345311Search in Google Scholar PubMed PubMed Central

[12] Lindheimer MD, Taler SJ, Cunningham FG. ASH position article: hypertension in pregnancy. J Am Soc Hypertens. 2008;2:484–9.10.1016/j.jash.2008.10.001Search in Google Scholar

[13] Lowe SA, Brown MA, Dekker GA, Gatt S, McLintock CK, McMahon LP, et al., for the Society of Obstetric Medicine of Australia and New Zealand. Guidelines for the management of hypertensive disorders of pregnancy 2008. Aust N Z J Obstet Gynaecol. 2009;49:242–6.10.1111/j.1479-828X.2009.01003.xSearch in Google Scholar

[14] Magee LA, Helewa ME, Moutquin JM, von Dadelszen P, Hypertension Guideline Committee, Society of Obstetricians and Gynaecologists of Canada. SOGC guidelines; diagnosis, evaluation and management of the hypertensive disorders of pregnancy. J Obstet Gynaecol. Can. 2008;30:1–48.Search in Google Scholar

[15] Mathews LS, Vale WW. Expression cloning of an activin receptor, a predicted transmembrane serin kinase. Cell. 1991;65:973–82.10.1016/0092-8674(91)90549-ESearch in Google Scholar

[16] Molvarec A, Jermendy A, Nagy B, Kovács M, Várkonyi T, Hupuczi P, et al. Association between tumor necrosis factor (TNF)-alpha G-308A gene polymorphism and preeclampsia complicated by severe fetal growth restriction. Clin Chim Acta. 2008;392:52–7.10.1016/j.cca.2008.03.009Search in Google Scholar PubMed

[17] Molvarec A, Vér A, Fekete A, Rosta K, Derzbach L, Derzsy Z, et al. Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia. Hypertens Res. 2007;30:205–11.10.1291/hypres.30.205Search in Google Scholar PubMed

[18] Moses EK, Fitzpatrick E, Freed KA, Dyer TD, Forrest S, Elliott K, et al. Objective prioritization of positional candidate genes at a quantitative trait locus for pre-eclampsia on 2q22. Mol Hum Reprod. 2006;12:505–12.10.1093/molehr/gal056Search in Google Scholar PubMed

[19] Moses EK, Lade JA, Guo G, Wilton AN, Grehan M, Freed K, et al. A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2. Am J Hum Genet. 2000;67:1581–5.10.1086/316888Search in Google Scholar PubMed PubMed Central

[20] Ong S, Lash G, Baker PN. Angiogenesis and placental growth in normal and compromised pregnancies. Best Pract Res Clin Obstet Gynaecol. 2000;14:969–80.10.1053/beog.2000.0138Search in Google Scholar PubMed

[21] Poon LC, Kametas NA, Maiz N, Akolekar R, Nicolaides KH. First-trimester prediction of hypertensive disorders in pregnancy. Hypertension. 2009;53:812–8.10.1161/HYPERTENSIONAHA.108.127977Search in Google Scholar PubMed

[22] Rana S, Karumanchi SA, Levine RJ, Venkatesha S, Rauh-Hain JA, Tamez H, et al. Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia. Hypertension. 2007;50:137–42.10.1161/HYPERTENSIONAHA.107.087700Search in Google Scholar PubMed

[23] Roberts JM, Cooper DW. Pathogenesis and genetics of pre-eclampsia. Lancet. 2001;357:53–6.10.1016/S0140-6736(00)03577-7Search in Google Scholar

[24] Roten LT, Johnson MP, Forsmo S, Fitzpatrick E, Dyer TD, Brennecke SP, et al. Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study). Eur J Hum Genet. 2009;17:250–7.10.1038/ejhg.2008.158Search in Google Scholar

[25] Salonen RH, Lichtenstein P, Lipworth L, Cnattingius S. Genetic effects on the liability of developing pre-eclampsia and gestational hypertension. Am J Med Genet. 2000;91: 256–60.10.1002/(SICI)1096-8628(20000410)91:4<256::AID-AJMG3>3.0.CO;2-TSearch in Google Scholar

[26] Sutherland A, Cooper DW, Howie PW, Liston WA, MacGillivray I. The incidence of severe pre-eclampsia amongst mothers and mothers-in-law of pre-eclamptics and controls. Br J Obstet Gynaecol. 1981;88:785–91.10.1111/j.1471-0528.1981.tb01304.xSearch in Google Scholar

[27] Thornton JG, MacDonald AM. Twin mothers, pregnancy hypertension and pre-eclampsia. Br J Obstet Gynaecol. 1999;106:570–5.10.1111/j.1471-0528.1999.tb08326.xSearch in Google Scholar

[28] Thornton JG, Onwude JL. Pre-eclampsia: discordance among identical twins. Br Med J. 1991;303:1241–2.10.1136/bmj.303.6812.1241Search in Google Scholar

[29] Tuffnell DJ, Shennan AH, Waugh JJS, Walker JJ. The management of severe pre-eclampsia/eclampsia, guideline number 10(A). London: Royal College of Obstetricians and Gynaecologists; 2006.Search in Google Scholar

[30] Uzan J, Carbonnel M, Piconne O, Asmar R, Ayoubi JM. Pre-eclampsia: pathophysiology, diagnosis and management. Vasc Health Risk Manag. 2011;7:467–74.Search in Google Scholar

[31] von Dadelszen P, Magee LA, Roberts JM. Subclassification of preeclampsia. Hypertens Pregnancy. 2003;22: 143–8.10.1081/PRG-120021060Search in Google Scholar

[32] Zhang Z, Zhao Y, Batres Y, Lin MF, Ying SY. Regulation of growth and prostatic marker expression by activin A in an androgen-sensitive prostate cancer cell line LNCAP. Biochem Biophys Res Commun. 1997;234:362–5.10.1006/bbrc.1997.6649Search in Google Scholar

[33] Zusterzeel PL, Peters WH, Visser W, Hermsen KJ, Roelofs HM, Steegers EA. A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia. J Med Genet. 2001;38:234–7.10.1136/jmg.38.4.234Search in Google Scholar