Neonatal Autoimmune Hypothyroidism: A Patient Report
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Lorenzo Pavone
ABSTRACT
Background: Acquired primary hypothyroidism in neonates and infants under 3 years of age is very rare. Herein we report the case of an infant female affected by acquired autoimmune hypothyroidism.
Patient report: The infant was transferred to the Pediatric Clinic, University of Catania, Italy for evaluation of dysmorphic features, growth and motor retardation, and hypothyroidism on laboratory testing. Neonatal screening test for TSH and PKU was negative. An ultrasound scan showed a non-homogeneous thyroid gland which was increased in volume. Based on the laboratory results, the diagnosis of autoimmune hypothyroidism was made and L-thyroxine treatment was initiated at 50 μg/day.
Conclusions: Autoimmune hypothyroidism in infancy is rare, but early recognition and therapy are essential to prevent neurologic damage and growth deficits. In this patient we would like to underline the early age of appearance of autoimmune thyroid disease and the possible onset of pathologic events before birth.
© Freund Publishing House Ltd.
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Artikel in diesem Heft
- The Soy That Surrounds Us: An Endless Debate
- Soy as an Endocrine Disruptor: Cause for Caution?
- Mass Ascites in Mulibrey Nanism
- Delayed Gastric Emptying in Patients with Prader Willi Syndrome
- Age and Sex Differences in Fat Distribution in Non-Obese Japanese Children
- Premature Thelarche in Taiwanese Girls
- Growth Hormone, Insulin Like Growth Factor-1, and Insulin-like Growth Factor-Binding Protein-3 Levels in the Neonatal Period: A Preliminary Study
- Bone Maturation in 1788 Children and Adolescents with Diabetes Mellitus Type 1
- Serum Thyroid Hormone Levels in Preterm Infants Born before 33 Weeks of Gestation and Association of Transient Hypothyroxinemia with Postnatal Characteristics
- Birth Length is a Predictor of Adiponectin Levels in Japanese Young Children
- Genotype-Phenotype Correlation in CAH Patients with Severe CYP21A2 Point Mutations in the Republic of Macedonia
- Benign Transient Hyperphosphatasemia of Infancy. A Common Benign Scenario, a Big Concern for a Pediatrician
- Scarcity Despite Wealth: Osteopetrorickets
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- Insulin Resistance and the Metabolic Syndrome in Obese Children Referred to an Obesity Center
- Severe Dietary Protein Sensitivity and Hyperinsulinemic Hypoglycemia in a Patient with Heterozygous Mutation in HADH Gene
- Neonatal Autoimmune Hypothyroidism: A Patient Report
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- Investigation of Acquired Von Willebrand Syndrome in Children with Hypothyroidism: Reversal after Treatment with Thyroxine
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