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Insulin Resistance and the Metabolic Syndrome in Obese Children Referred to an Obesity Center

  • J. Rotteveel , A. Felius , M. M. van Weissenbruch and H. A. Delemarre–Van de Waal
Published/Copyright: December 22, 2010
Journal of Pediatric Endocrinology and Metabolism
From the journal Volume 23 Issue 9

ABSTRACT

Objective: The aim of this study was to describe insulin resistance and the metabolic syndrome in obese children and adolescents.

Subjects: The cohort consisted of 518 patients, 250 boys, 268 girls, age ± sd: 11.8 ± 3.2 years, BMIsds ± sd: 2.94 ± 0.5. A standard OGTT was performed.

Results: Impaired glucose tolerance was found in 9.4% of the boys and 5.5% of the girls. Impaired fasting glucose was found in 12.4% of the boys and 11.6% of the girls. The metabolic syndrome was present in 13.9% of children of 10 years or older. The proportion in which the metabolic syndrome was diagnosed was essentially not altered when pubertal groups were used instead of age groups.

Conclusion: Both impaired fasting glucose and impaired glucose tolerance as well as the metabolic syndrome are highly prevalent among obese children and adolescents.


Corresponding author: J. Rotteveel,

Published Online: 2010-12-22
Published in Print: 2010-September

© Freund Publishing House Ltd.

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